Q65GY3 (FENR1_BACLD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase 1
Short name=FNR 1
Short name=Fd-NADP+ reductase 1
EC=1.18.1.2

Gene names

Ordered Locus Names:

BLi02810, BL02042

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Ferredoxin--NADP reductase 1 HAMAP MF_01685		PRO_0000364797
Sites
	Binding site	36	1	FAD By similarity
	Binding site	44	1	FAD By similarity
	Binding site	48	1	FAD By similarity
	Binding site	88	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	123	1	FAD; via amide nitrogen By similarity
	Binding site	290	1	FAD By similarity
	Binding site	331	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q65GY3 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 7360705E89C0111A	FASTA	349	38,342
	10 20 30 40 50 60 MSRNELFDVT VIGGGPAGLY SAFYSGLRGM KAKIIEYQPM LGGKVHVYPE KMIWDVGGLT 70 80 90 100 110 120 PISGAKLIEQ LVQQGLTFHP EVLLNEKVES IARNEEGLFE LHTAASGVHL SKTVIVAVGG 130 140 150 160 170 180 GILNPQKLQI EGAERFEVSN LNYTVKSLQH FKDKTVIVSG GGNSAVDWAN ELEPVAKKVY 190 200 210 220 230 240 LAYRKDALSG HEAQVDQLLN SSVSCFFHTE ITKLIASEDH EVIERVELTN AQTGEVMELP 250 260 270 280 290 300 VDEVVINHGY ERDTSLLENS RLDVTRVDDY YIAGTSNCQS SVPGLYAAGD IVHYEGKLHL 310 320 330 340 IAGAFQDAAN AVNSAKRFID PEAHKSAMVS SHNEVFKERN RELVKKMFV

References

[1]

"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 / ATCC 14580.

[2]

"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:R77.1-R77.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 / ATCC 14580.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000002 Genomic DNA. Translation: AAU24315.1. AE017333 Genomic DNA. Translation: AAU41681.1.
RefSeq	YP_079953.1. NC_006270.3. YP_092374.1. NC_006322.1.
3D structure databases
ProteinModelPortal	Q65GY3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q65GY3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000058018; EBBACP00000056549; EBBACG00000058009. EBBACT00000058693; EBBACP00000057126; EBBACG00000058684.
GeneID	3028262. 3097980.
GenomeReviews	Gene locus BLi02810 in contig AE017333_GR. Gene locus BL02042 in contig CP000002_GR.
KEGG	bld:BLi02810. bli:BL02042.
NMPDR	fig|279010.5.peg.3102.
PATRIC	18951320. VBIBacLic203714_2861.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
GeneTree	EBGT00050000000432.
HOGENOM	HBG669726.
OMA	FNTSITK.
ProtClustDB	CLSK904552.
Enzyme and pathway databases
BioCyc	BLIC279010-1:BLI02810-MONOMER. BLIC279010:BL02042-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR1_BACLD

Accession

Primary (citable) accession number: Q65GY3
Secondary accession number(s): Q62SE4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program