Q65G92 (Q65G92_BACLD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA polymerase RuleBase RU004460
EC=2.7.7.7 RuleBase RU004460

Gene names

Name:	polA EMBL AAU41922.1
Ordered Locus Names:	BL00394, BLi03057 EMBL AAU41922.1

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP] EMBL AAU41922.1

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus subtilis group › Bacillus licheniformis

Protein attributes

Sequence length	879 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Sequence similarities	Belongs to the DNA polymerase type-A family. RuleBase RU004459 Contains 1 5'-3' exonuclease domain. SAAS SAAS002421

Ontologies

Keywords
Biological process	DNA replication RuleBase RU004460
Ligand	DNA-binding RuleBase RU004460
Molecular function	Nucleotidyltransferase RuleBase RU004460 EMBL AAU41922.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: InterPro DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro 5'-3' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: UniProtKB-KW DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q65G92 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 1D0C637D96D8CDDD	FASTA	879	99,210
	10 20 30 40 50 60 MTERKKLVLV DGNSLAYRAF FALPLLSNEK GIHTNAVYGF TTILMKMLEE EKPTHMLVAF 70 80 90 100 110 120 DAGKTTFRHK TFKEYKGGRQ KTPPELSEQL PFIRELLDAY RISRYELENY EADDIIGTLA 130 140 150 160 170 180 KSAEKDGFEV KIFSGDKDLT QLATEGTTVA ITKKGITDVE YYTPEHVREK YGLTPEQIID 190 200 210 220 230 240 MKGLMGDSSD NIPGVPGVGE KTAIKLLKQF HTVEELLSSI DEVSGKKLKE KLEEFKEQAL 250 260 270 280 290 300 MSKELATITT EAPLEVSLDS LGYEGFDREA VVKIFKDLGF HSLLERIGEE AGEKEEEQLE 310 320 330 340 350 360 EIDVMIKTDI TDDLFASPAS LVVEQLGDNY HEAPILGFSI VNEHGAFFIP EETAVQSDCF 370 380 390 400 410 420 KEWAEDESKK KWVFDAKRAA VALRWRGIEL KGAEFDVLLA AYIINPGHSY DDVASVAKEH 430 440 450 460 470 480 QLHIVSADEA VYGKGAKQAV PDEKELADHL ARKAKAISLL REKLLDELEE NEQLELFEAL 490 500 510 520 530 540 EMPLAHILGE MESIGVQVDV DRLKKMGEEL SAKLAEYEKK IHESAGETFN INSPKQLGVI 550 560 570 580 590 600 LFDKLGLPVV KKTKTGYSTS ADVLEKLRDK HVIIEDILHY RQIGKLQSTY VEGLLKVIKK 610 620 630 640 650 660 DSHKVHTRFN QALTQTGRLS STDPNLQNIP IRLEEGRKIR QAFVPSQKGW LIFAADYSQI 670 680 690 700 710 720 ELRVLAHISK DKNLIEAFTN DMDVHTKTAM DVFHVSEEEV TPAMRRQAKA VNFGIVYGIS 730 740 750 760 770 780 DYGLSQNLGI TRKEAAAFIE RYFHSFQGVK EYMEETVQEA KQRGYVTTLL SRRRYIPELT 790 800 810 820 830 840 SRNFNLRSFA ERTAMNTPIQ GSAADIIKKA MIDMADKLKE KNLQAKLLLQ VHDELIFEAP 850 860 870 EDEIKVLEKL VPEVMEHALE LDVPLKVDCA SGPSWYDAK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:R77.1-R77.12(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 / ATCC 14580 [Novozymes].
[2]	"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 EMBL AAU41922.1 and DSM 13 / ATCC 14580 [Goettingen].
[3]	Wiegand S., Hertel R., Dietrich S., Volland S., Liesegang H. Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: DSM 13 EMBL AAU41922.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000002 Genomic DNA. Translation: AAU24563.1. AE017333 Genomic DNA. Translation: AAU41922.1.
RefSeq	YP_006714393.1. NC_006322.1. YP_080201.1. NC_006270.3.
3D structure databases
SMR	Q65G92. Positions 310-879.
ModBase	Search...
Protein-protein interaction databases
STRING	279010.BL00394.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAU24563; AAU24563; BL00394. AAU41922; AAU41922; BLi03057.
GeneID	3028928. 3098657.
KEGG	bld:BLi03057. bli:BL00394.
PATRIC	18951844. VBIBacLic203714_3122.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0258.
HOGENOM	HOG000020998.
KO	K02335.
OMA	EQRRYAK.
ProtClustDB	PRK05755.
Enzyme and pathway databases
BioCyc	BLIC279010:GJ2P-3032-MONOMER.
Family and domain databases
InterPro	IPR002562. 3'-5'_exonuclease_dom. IPR020046. 5-3_exonucl_a-hlix_arch_N. IPR020045. 5-3_exonuclease_C. IPR002421. 5-3_exonuclease_N. IPR019760. DNA-dir_DNA_pol_A_CS. IPR001098. DNA-dir_DNA_pol_A_palm_dom. IPR018320. DNA_polymerase_1. IPR002298. DNA_polymerase_A. IPR008918. HhH2. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. IPR012337. RNaseH-like_dom. [Graphical view]
Pfam	PF01367. 5_3_exonuc. 1 hit. PF02739. 5_3_exonuc_N. 1 hit. PF00476. DNA_pol_A. 1 hit. [Graphical view]
PRINTS	PR00868. DNAPOLI.
SMART	SM00474. 35EXOc. 1 hit. SM00475. 53EXOc. 1 hit. SM00278. HhH1. 2 hits. SM00279. HhH2. 1 hit. SM00482. POLAc. 1 hit. [Graphical view]
SUPFAM	SSF47807. 5_3_exo_C. 1 hit. SSF53098. RNaseH_fold. 1 hit.
TIGRFAMs	TIGR00593. pola. 1 hit.
PROSITE	PS00447. DNA_POLYMERASE_A. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q65G92_BACLD

Accession

Primary (citable) accession number: Q65G92
Secondary accession number(s): Q62RP7

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2004
Last sequence update:	October 25, 2004
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)