Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q65FV7

- PCKA_BACLD

UniProt

Q65FV7 - PCKA_BACLD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoenolpyruvate carboxykinase [ATP]

Gene

pckA

Organism
Bacillus licheniformis (strain DSM 13 / ATCC 14580)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.UniRule annotation

Catalytic activityi

ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2.UniRule annotation

Cofactori

Binds 1 manganese ion per subunit.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei56 – 561SubstrateUniRule annotation
Binding sitei192 – 1921SubstrateUniRule annotation
Metal bindingi198 – 1981ManganeseUniRule annotation
Binding sitei198 – 1981ATPUniRule annotation
Binding sitei198 – 1981SubstrateUniRule annotation
Metal bindingi217 – 2171Manganese; via tele nitrogenUniRule annotation
Binding sitei217 – 2171ATPUniRule annotation
Metal bindingi254 – 2541ManganeseUniRule annotation
Binding sitei282 – 2821ATPUniRule annotation
Binding sitei319 – 3191ATPUniRule annotation
Binding sitei319 – 3191SubstrateUniRule annotation
Binding sitei444 – 4441ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi233 – 2419ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW
  3. phosphoenolpyruvate carboxykinase (ATP) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Gluconeogenesis

Keywords - Ligandi

ATP-binding, Manganese, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLIC279010:GJ2P-3168-MONOMER.
UniPathwayiUPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxykinase [ATP]UniRule annotation (EC:4.1.1.49UniRule annotation)
Short name:
PCKUniRule annotation
Short name:
PEP carboxykinaseUniRule annotation
Short name:
PEPCKUniRule annotation
Gene namesi
Name:pckAUniRule annotation
Ordered Locus Names:BLi03197, BL00839
OrganismiBacillus licheniformis (strain DSM 13 / ATCC 14580)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000000606: Chromosome, UP000000608: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 527527Phosphoenolpyruvate carboxykinase [ATP]PRO_0000236919Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi279010.BL00839.

Structurei

3D structure databases

ProteinModelPortaliQ65FV7.
SMRiQ65FV7. Positions 16-523.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoenolpyruvate carboxykinase [ATP] family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1866.
HOGENOMiHOG000271471.
KOiK01610.
OMAiGADPEHY.
OrthoDBiEOG6DG2RK.

Family and domain databases

Gene3Di3.40.449.10. 1 hit.
3.90.228.20. 2 hits.
HAMAPiMF_00453. PEPCK_ATP.
InterProiIPR001272. PEP_carboxykinase_ATP.
IPR013035. PEP_carboxykinase_C.
IPR008210. PEP_carboxykinase_N.
[Graphical view]
PfamiPF01293. PEPCK_ATP. 1 hit.
[Graphical view]
PIRSFiPIRSF006294. PEP_crbxkin. 1 hit.
SUPFAMiSSF68923. SSF68923. 1 hit.
TIGRFAMsiTIGR00224. pckA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q65FV7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSVDLTTDL QTLLTGENVQ MNLSVPHLVE KILERKEGVL TSSGAVRATT
60 70 80 90 100
GTYTGRSPKD KFIVEEASTK DKIDWGAVNQ PISEAAFDRL YAKVLGYLKE
110 120 130 140 150
RDELYVFEGF AGADEKYRLP ITVVNEFAWH NLFARQLFIR PEEHDKKPEE
160 170 180 190 200
QPFTILSAPH FKADPLVDGT RSETFIIVSF EKRTILIGGT EYAGEMKKSI
210 220 230 240 250
FSIMNFLLPE QNILPMHCSA NIGEEGGTAL FFGLSGTGKT TLSADPKRKL
260 270 280 290 300
IGDDEHGWSS TGVFNIEGGC YAKCINLSEE KEPQIYNAIR FGSVLENVVV
310 320 330 340 350
DSKTGEPDYS DSFYTENTRA AYPIDAIDNI VKPSIAAHPQ TIVFLTADAF
360 370 380 390 400
GVLPPISKLT KEQAMYHFLS GYTSKLAGTE RGITTPEATF STCFGSPFLP
410 420 430 440 450
LPAHVYAEML GRKIDEHGVG VFLVNTGWTG GGYGTGERMS LAYTRAMVQA
460 470 480 490 500
AIEGELDKAE MRTDRIFGLH SPVHVPGVPD QVLDPAKTWT DENEYEEKAI
510 520
HLAKAFKQNF KKFSNTENIE KAGGPLV
Length:527
Mass (Da):58,167
Last modified:October 25, 2004 - v1
Checksum:iBE2002BCB9FF58C0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017333 Genomic DNA. Translation: AAU42057.1.
CP000002 Genomic DNA. Translation: AAU24695.1.
RefSeqiYP_006714528.1. NC_006322.1.
YP_080333.1. NC_006270.3.

Genome annotation databases

EnsemblBacteriaiAAU24695; AAU24695; BL00839.
AAU42057; AAU42057; BLi03197.
GeneIDi3027890.
3099051.
KEGGibld:BLi03197.
bli:BL00839.
PATRICi18952140. VBIBacLic203714_3270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017333 Genomic DNA. Translation: AAU42057.1 .
CP000002 Genomic DNA. Translation: AAU24695.1 .
RefSeqi YP_006714528.1. NC_006322.1.
YP_080333.1. NC_006270.3.

3D structure databases

ProteinModelPortali Q65FV7.
SMRi Q65FV7. Positions 16-523.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 279010.BL00839.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU24695 ; AAU24695 ; BL00839 .
AAU42057 ; AAU42057 ; BLi03197 .
GeneIDi 3027890.
3099051.
KEGGi bld:BLi03197.
bli:BL00839.
PATRICi 18952140. VBIBacLic203714_3270.

Phylogenomic databases

eggNOGi COG1866.
HOGENOMi HOG000271471.
KOi K01610.
OMAi GADPEHY.
OrthoDBi EOG6DG2RK.

Enzyme and pathway databases

UniPathwayi UPA00138 .
BioCyci BLIC279010:GJ2P-3168-MONOMER.

Family and domain databases

Gene3Di 3.40.449.10. 1 hit.
3.90.228.20. 2 hits.
HAMAPi MF_00453. PEPCK_ATP.
InterProi IPR001272. PEP_carboxykinase_ATP.
IPR013035. PEP_carboxykinase_C.
IPR008210. PEP_carboxykinase_N.
[Graphical view ]
Pfami PF01293. PEPCK_ATP. 1 hit.
[Graphical view ]
PIRSFi PIRSF006294. PEP_crbxkin. 1 hit.
SUPFAMi SSF68923. SSF68923. 1 hit.
TIGRFAMsi TIGR00224. pckA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential."
    Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13 / ATCC 14580.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13 / ATCC 14580.

Entry informationi

Entry nameiPCKA_BACLD
AccessioniPrimary (citable) accession number: Q65FV7
Secondary accession number(s): Q62RB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 25, 2004
Last modified: October 29, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3