SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q65FV7

- PCKA_BACLD

UniProt

Q65FV7 - PCKA_BACLD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoenolpyruvate carboxykinase [ATP]

Gene
pckA, BLi03197, BL00839
Organism
Bacillus licheniformis (strain DSM 13 / ATCC 14580)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA By similarity.UniRule annotation

Catalytic activityi

ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2.UniRule annotation

Cofactori

Binds 1 manganese ion per subunit By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei56 – 561Substrate By similarity
Binding sitei192 – 1921Substrate By similarity
Metal bindingi198 – 1981Manganese By similarity
Binding sitei198 – 1981ATP By similarity
Binding sitei198 – 1981Substrate By similarity
Metal bindingi217 – 2171Manganese; via tele nitrogen By similarity
Binding sitei217 – 2171ATP By similarity
Metal bindingi254 – 2541Manganese By similarity
Binding sitei282 – 2821ATP By similarity
Binding sitei319 – 3191ATP By similarity
Binding sitei319 – 3191Substrate By similarity
Binding sitei444 – 4441ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi233 – 2419ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW
  3. phosphoenolpyruvate carboxykinase (ATP) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Gluconeogenesis

Keywords - Ligandi

ATP-binding, Manganese, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLIC279010:GJ2P-3168-MONOMER.
UniPathwayiUPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxykinase [ATP] (EC:4.1.1.49)
Short name:
PCK
Short name:
PEP carboxykinase
Short name:
PEPCK
Gene namesi
Name:pckA
Ordered Locus Names:BLi03197, BL00839
OrganismiBacillus licheniformis (strain DSM 13 / ATCC 14580)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000000606: Chromosome, UP000000608: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 527527Phosphoenolpyruvate carboxykinase [ATP]UniRule annotationPRO_0000236919Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi279010.BL00839.

Structurei

3D structure databases

ProteinModelPortaliQ65FV7.
SMRiQ65FV7. Positions 16-523.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1866.
HOGENOMiHOG000271471.
KOiK01610.
OMAiGADPEHY.
OrthoDBiEOG6DG2RK.

Family and domain databases

Gene3Di3.40.449.10. 1 hit.
3.90.228.20. 2 hits.
HAMAPiMF_00453. PEPCK_ATP.
InterProiIPR001272. PEP_carboxykinase_ATP.
IPR013035. PEP_carboxykinase_C.
IPR008210. PEP_carboxykinase_N.
[Graphical view]
PfamiPF01293. PEPCK_ATP. 1 hit.
[Graphical view]
PIRSFiPIRSF006294. PEP_crbxkin. 1 hit.
SUPFAMiSSF68923. SSF68923. 1 hit.
TIGRFAMsiTIGR00224. pckA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q65FV7-1 [UniParc]FASTAAdd to Basket

« Hide

MNSVDLTTDL QTLLTGENVQ MNLSVPHLVE KILERKEGVL TSSGAVRATT    50
GTYTGRSPKD KFIVEEASTK DKIDWGAVNQ PISEAAFDRL YAKVLGYLKE 100
RDELYVFEGF AGADEKYRLP ITVVNEFAWH NLFARQLFIR PEEHDKKPEE 150
QPFTILSAPH FKADPLVDGT RSETFIIVSF EKRTILIGGT EYAGEMKKSI 200
FSIMNFLLPE QNILPMHCSA NIGEEGGTAL FFGLSGTGKT TLSADPKRKL 250
IGDDEHGWSS TGVFNIEGGC YAKCINLSEE KEPQIYNAIR FGSVLENVVV 300
DSKTGEPDYS DSFYTENTRA AYPIDAIDNI VKPSIAAHPQ TIVFLTADAF 350
GVLPPISKLT KEQAMYHFLS GYTSKLAGTE RGITTPEATF STCFGSPFLP 400
LPAHVYAEML GRKIDEHGVG VFLVNTGWTG GGYGTGERMS LAYTRAMVQA 450
AIEGELDKAE MRTDRIFGLH SPVHVPGVPD QVLDPAKTWT DENEYEEKAI 500
HLAKAFKQNF KKFSNTENIE KAGGPLV 527
Length:527
Mass (Da):58,167
Last modified:October 25, 2004 - v1
Checksum:iBE2002BCB9FF58C0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017333 Genomic DNA. Translation: AAU42057.1.
CP000002 Genomic DNA. Translation: AAU24695.1.
RefSeqiYP_006714528.1. NC_006322.1.
YP_080333.1. NC_006270.3.

Genome annotation databases

EnsemblBacteriaiAAU24695; AAU24695; BL00839.
AAU42057; AAU42057; BLi03197.
GeneIDi3027890.
3099051.
KEGGibld:BLi03197.
bli:BL00839.
PATRICi18952140. VBIBacLic203714_3270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017333 Genomic DNA. Translation: AAU42057.1 .
CP000002 Genomic DNA. Translation: AAU24695.1 .
RefSeqi YP_006714528.1. NC_006322.1.
YP_080333.1. NC_006270.3.

3D structure databases

ProteinModelPortali Q65FV7.
SMRi Q65FV7. Positions 16-523.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 279010.BL00839.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU24695 ; AAU24695 ; BL00839 .
AAU42057 ; AAU42057 ; BLi03197 .
GeneIDi 3027890.
3099051.
KEGGi bld:BLi03197.
bli:BL00839.
PATRICi 18952140. VBIBacLic203714_3270.

Phylogenomic databases

eggNOGi COG1866.
HOGENOMi HOG000271471.
KOi K01610.
OMAi GADPEHY.
OrthoDBi EOG6DG2RK.

Enzyme and pathway databases

UniPathwayi UPA00138 .
BioCyci BLIC279010:GJ2P-3168-MONOMER.

Family and domain databases

Gene3Di 3.40.449.10. 1 hit.
3.90.228.20. 2 hits.
HAMAPi MF_00453. PEPCK_ATP.
InterProi IPR001272. PEP_carboxykinase_ATP.
IPR013035. PEP_carboxykinase_C.
IPR008210. PEP_carboxykinase_N.
[Graphical view ]
Pfami PF01293. PEPCK_ATP. 1 hit.
[Graphical view ]
PIRSFi PIRSF006294. PEP_crbxkin. 1 hit.
SUPFAMi SSF68923. SSF68923. 1 hit.
TIGRFAMsi TIGR00224. pckA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential."
    Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13 / ATCC 14580.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13 / ATCC 14580.

Entry informationi

Entry nameiPCKA_BACLD
AccessioniPrimary (citable) accession number: Q65FV7
Secondary accession number(s): Q62RB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 25, 2004
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi