Q65FN2 (TGL_BACLD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-glutamine gamma-glutamyltransferase
EC=2.3.2.13

Alternative name(s):
Transglutaminase
Short name=TGase

Gene names

Name:	tgl
Ordered Locus Names:	BLi03298, BL02523

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links By similarity. HAMAP MF_00727
Catalytic activity	Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3. HAMAP MF_00727
Sequence similarities	Belongs to the bacillus TGase family.

Ontologies

Keywords
Biological process	Sporulation
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 245	245	Protein-glutamine gamma-glutamyltransferase HAMAP MF_00727		PRO_1000197969

Sequences

	Sequence		Length	Mass (Da)
	Q65FN2 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: F85E504E0B140A19	FASTA	245	28,178
	10 20 30 40 50 60 MISVSGYRLR PEDIEKLNVS QTQRDIANRM LAMPSGYRYG SISELLFELR FREHTVKSAR 70 80 90 100 110 120 ELINSGAKFA TFSKTYGNEE FWRVTPEGAL ELKYRAPASK AIRNIFESGP SYAFECATAI 130 140 150 160 170 180 VIIFYMALLK TIGDQTFDRN YQRIILYDWH YERLPIYTDK GNDYLPGDCL YFKNPEFDPS 190 200 210 220 230 240 RPQWRGENAI LLENNLYAAH GLGILSGETI IEKLNGLRKP HAQTSAYLLS QVTRVDIPAL IQMIR

References

[1]

"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 / ATCC 14580.

[2]

"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:R77.1-R77.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 / ATCC 14580.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000002 Genomic DNA. Translation: AAU24768.1. AE017333 Genomic DNA. Translation: AAU42132.1.
RefSeq	YP_080406.1. NC_006270.3. YP_092825.1. NC_006322.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q65FN2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000058210; EBBACP00000056741; EBBACG00000058201. EBBACT00000058681; EBBACP00000057114; EBBACG00000058672.
GeneID	3028678. 3099384.
GenomeReviews	Gene locus BLi03298 in contig AE017333_GR. Gene locus BL02523 in contig CP000002_GR.
KEGG	bld:BLi03298. bli:BL02523.
NMPDR	fig|279010.5.peg.3524.
PATRIC	18952348. VBIBacLic203714_3350.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG12337.
GeneTree	EBGT00050000001129.
HOGENOM	HBG339895.
OMA	FECATAI.
ProtClustDB	PRK03187.
Enzyme and pathway databases
BioCyc	BLIC279010-1:BLI03298-MONOMER. BLIC279010:BL02523-MONOMER.
Family and domain databases
HAMAP	MF_00727. Tgl. [Tree]
InterPro	IPR020916. Gln_gamma-glutamylTfrase_bac. [Graphical view]
KO	K00686.
ProDom	PD119415. PD119415. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

TGL_BACLD

Accession

Primary (citable) accession number: Q65FN2
Secondary accession number(s): Q62R42

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program