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Protein

Uronate isomerase

Gene

uxaC

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:BLi03516, BL00708
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001727591 – 473Uronate isomeraseAdd BLAST473

Interactioni

Protein-protein interaction databases

STRINGi279010.BLi03516.

Structurei

3D structure databases

ProteinModelPortaliQ65F21.
SMRiQ65F21.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q65F21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPFLNDDFL LTNETSKVLY HQYAKGMPII DYHCHLSPKE IYENKTFKNL
60 70 80 90 100
TEVWLYGDHY KWRAMRANGI SEEFITGDAS DEEKFSAWAR TVPMTIGNPL
110 120 130 140 150
YHWTHLELRR FFGIDDRLDE KSAPHIWERV NEQLAGGGFG ARDLIEKSNV
160 170 180 190 200
ETVVTTDDPT DSLEYHVKLK DEDFNVSVLP GFRPDKAMEI NQEGFAAWVR
210 220 230 240 250
KLETASGMKI ANYDDFLKAL KNRIDFFHEA GGRISDHAIN QMMYTETDES
260 270 280 290 300
EVRPIFAKVM NGESASPEEE CKFKSLTLHF LGTCYAEKGW AMQLHINALR
310 320 330 340 350
NNSSKMYRKL GPDTGYDAIN DQDIAKPLCS FLDSLDRKDA LPKTILYSLN
360 370 380 390 400
PRDNVVISSL CGSFQDGRIP GKIQHGTAWW FNDTKDGMLE QMKSLANIGL
410 420 430 440 450
LSRFIGMLTD SRSFLSYTRH EYFRRLLCDV IGTWVENGEA PDDIELLGRI
460 470
VKGICYENAK HYFQFEVKDR LKA
Length:473
Mass (Da):54,379
Last modified:October 25, 2004 - v1
Checksum:iF01EAF06663576AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017333 Genomic DNA. Translation: AAU42343.1.
CP000002 Genomic DNA. Translation: AAU24973.1.
RefSeqiWP_009329570.1. NC_006322.1.

Genome annotation databases

EnsemblBacteriaiAAU24973; AAU24973; BL00708.
AAU42343; AAU42343; BLi03516.
GeneIDi3029362.
KEGGibld:BLi03516.
bli:BL00708.
PATRICi18952796. VBIBacLic203714_3574.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017333 Genomic DNA. Translation: AAU42343.1.
CP000002 Genomic DNA. Translation: AAU24973.1.
RefSeqiWP_009329570.1. NC_006322.1.

3D structure databases

ProteinModelPortaliQ65F21.
SMRiQ65F21.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi279010.BLi03516.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU24973; AAU24973; BL00708.
AAU42343; AAU42343; BLi03516.
GeneIDi3029362.
KEGGibld:BLi03516.
bli:BL00708.
PATRICi18952796. VBIBacLic203714_3574.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_BACLD
AccessioniPrimary (citable) accession number: Q65F21
Secondary accession number(s): Q62QI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: October 25, 2004
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.