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Protein

Lactate utilization protein B

Gene

lutB

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi313Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi316Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi319Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi323Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi366Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi369Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi373Iron-sulfur 1 (4Fe-4S)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Lactate utilization protein BUniRule annotation
Gene namesi
Name:lutBUniRule annotation
Synonyms:yvfW
Ordered Locus Names:BLi03674, BL03457
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003839751 – 477Lactate utilization protein BAdd BLAST477

Interactioni

Protein-protein interaction databases

STRINGi279010.BLi03674.

Structurei

3D structure databases

ProteinModelPortaliQ65EM0.
SMRiQ65EM0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini304 – 3344Fe-4S ferredoxin-type 1UniRule annotationAdd BLAST31
Domaini353 – 3824Fe-4S ferredoxin-type 2UniRule annotationAdd BLAST30

Sequence similaritiesi

Belongs to the LutB/YkgF family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG1139. LUCA.
HOGENOMiHOG000262102.
KOiK18929.
OMAiHCPVYDK.

Family and domain databases

Gene3Di1.10.1060.10. 1 hit.
HAMAPiMF_02103. LutB. 1 hit.
InterProiView protein in InterPro
IPR004452. 4Fe-4S-bd.
IPR024569. 4Fe-4S-bd_C.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR009051. Helical_ferredxn.
IPR003741. LUD_dom.
IPR022825. LutB.
IPR037171. NagB/RpiA_transferase-like.
PANTHERiPTHR32479:SF10. PTHR32479:SF10. 1 hit.
PfamiView protein in Pfam
PF11870. DUF3390. 1 hit.
PF13183. Fer4_8. 1 hit.
PF02589. LUD_dom. 1 hit.
SUPFAMiSSF100950. SSF100950. 2 hits.
SSF46548. SSF46548. 1 hit.
TIGRFAMsiTIGR00273. TIGR00273. 1 hit.
PROSITEiView protein in PROSITE
PS00198. 4FE4S_FER_1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q65EM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMKIGTQKF KERVSDGLDN EFMRGAVSSA QERLRARRLE AAKELGNWEE
60 70 80 90 100
WRSLAEEIRQ HVLENLDYYL EQLAENVAKK GGHVFFAQTA EEATGYIRDV
110 120 130 140 150
VKKKNGKKIV KSKSMVTEEI NMNEALESDG CEVVETDLGE YILQIDDHDP
160 170 180 190 200
PSHIVAPALH KNKEQIRDVF KERIGYRNTE KPEELVMHAR AVLRKKFLEA
210 220 230 240 250
DIGITGCNFA IADTGSVSLV TNEGNGRLVT TIPKTQITVM GMERIVPSFD
260 270 280 290 300
EFEVLVGMLT RSAVGQRLTS YITALTGPRL PGEADGPEEF HLVIVDNGRS
310 320 330 340 350
NILGTEFQSV LQCIRCAACI NVCPVYRHVG GHSYGSIYSG PIGAVLSPLL
360 370 380 390 400
GGYDDYKELP YASSLCAACS EACPVKIPLH ELLLKHRQRI VEKEGRAPIS
410 420 430 440 450
EKLAMKAFGL GTSAPSLYKM GSKWAPAAMK PFKEDGKITK GPGPLKQWTQ
460 470
IRDFPAPNKS RFRDWFEDRR KEKGEDK
Length:477
Mass (Da):53,214
Last modified:October 25, 2004 - v1
Checksum:i892CD0FAF8303A03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017333 Genomic DNA. Translation: AAU42494.1.
CP000002 Genomic DNA. Translation: AAU25123.1.
RefSeqiWP_003185481.1. NC_006322.1.

Genome annotation databases

EnsemblBacteriaiAAU25123; AAU25123; BL03457.
AAU42494; AAU42494; BLi03674.
GeneIDi3029355.
KEGGibld:BLi03674.
bli:BL03457.

Similar proteinsi

Entry informationi

Entry nameiLUTB_BACLD
AccessioniPrimary (citable) accession number: Q65EM0
Secondary accession number(s): Q62Q37
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: October 25, 2004
Last modified: November 22, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families