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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BLi03971, BL03923
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002419831 – 556Arginine--tRNA ligaseAdd BLAST556

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi279010.BLi03971

Structurei

3D structure databases

ProteinModelPortaliQ65DS9
SMRiQ65DS9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiHGMSTRQ

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q65DS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIVEQMKDV LKQEIKEAVM KAGLAEESEI PEVVLEVPKD KSHGDYSTNM
60 70 80 90 100
AMQLARIAKK APRNIAEEIV ASFDKGKASI DKLDIAGPGF INFYMNNQYL
110 120 130 140 150
TKLIPAVLEA GEAYGETNIG GGERVQVEFV SANPTGNLHL GHARGAAVGD
160 170 180 190 200
SLCNVLEKAG YEVSREYYIN DAGNQINNLA LSVEARYFQA LGKDKPMPED
210 220 230 240 250
GYHGEDIKEI GQKLADEFGD RFVHEEESER LAFFREYGLK YELGKLREDL
260 270 280 290 300
ENFRVPFDVW YSETSLYQNG KIDQALEALR EKGHIYEEDG ATWFRSTAFG
310 320 330 340 350
DDKDRVLIKK DGSYTYLLPD IAYHKDKLDR GFQKLINVWG ADHHGYIPRM
360 370 380 390 400
KAAIEALGYD KETLEVEIIQ LVHLYKNGEK MKMSKRTGKA VTMRDLIDEV
410 420 430 440 450
GLDAVRYFFA MRSADTHMDF DLDLAVSTSN ENPVYYAQYA HARICSMLRQ
460 470 480 490 500
GEEKGISFEG NLDLTKIGSE KEYDLLKVIG SFPEAVADAA EKRIPHRITN
510 520 530 540 550
YIFELASVLH SFYNAEKVLD PADEEKSRAR LSLMKATQIT LNNALKLIGV

SAPEKM
Length:556
Mass (Da):62,656
Last modified:October 25, 2004 - v1
Checksum:i40FE575CDC203DAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017333 Genomic DNA Translation: AAU42785.1
CP000002 Genomic DNA Translation: AAU25411.1
RefSeqiWP_003186077.1, NC_006322.1

Genome annotation databases

EnsemblBacteriaiAAU25411; AAU25411; BL03923
AAU42785; AAU42785; BLi03971
GeneIDi3027964
KEGGibld:BLi03971
bli:BL03923

Similar proteinsi

Entry informationi

Entry nameiSYR_BACLD
AccessioniPrimary (citable) accession number: Q65DS9
Secondary accession number(s): Q62PA0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 25, 2004
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health