Reviewed, UniProtKB/Swiss-Prot Q65DS9 (SYR_BACLD)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BLi03971, BL03923

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	556 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 556	556	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000241983
Regions
	Motif	132 – 142	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q65DS9-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 40FE575CDC203DAC	FASTA	556	62,656
	10 20 30 40 50 60 MNIVEQMKDV LKQEIKEAVM KAGLAEESEI PEVVLEVPKD KSHGDYSTNM AMQLARIAKK 70 80 90 100 110 120 APRNIAEEIV ASFDKGKASI DKLDIAGPGF INFYMNNQYL TKLIPAVLEA GEAYGETNIG 130 140 150 160 170 180 GGERVQVEFV SANPTGNLHL GHARGAAVGD SLCNVLEKAG YEVSREYYIN DAGNQINNLA 190 200 210 220 230 240 LSVEARYFQA LGKDKPMPED GYHGEDIKEI GQKLADEFGD RFVHEEESER LAFFREYGLK 250 260 270 280 290 300 YELGKLREDL ENFRVPFDVW YSETSLYQNG KIDQALEALR EKGHIYEEDG ATWFRSTAFG 310 320 330 340 350 360 DDKDRVLIKK DGSYTYLLPD IAYHKDKLDR GFQKLINVWG ADHHGYIPRM KAAIEALGYD 370 380 390 400 410 420 KETLEVEIIQ LVHLYKNGEK MKMSKRTGKA VTMRDLIDEV GLDAVRYFFA MRSADTHMDF 430 440 450 460 470 480 DLDLAVSTSN ENPVYYAQYA HARICSMLRQ GEEKGISFEG NLDLTKIGSE KEYDLLKVIG 490 500 510 520 530 540 SFPEAVADAA EKRIPHRITN YIFELASVLH SFYNAEKVLD PADEEKSRAR LSLMKATQIT 550 LNNALKLIGV SAPEKM

References

[1]

"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:RESEARCH077.1-RESEARCH077.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017333 Genomic DNA. Translation: AAU42785.1. CP000002 Genomic DNA. Translation: AAU25411.1.
RefSeq	YP_081049.1. YP_093478.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q65DS9.
Genome annotation databases
GeneID	3027964. 3101407.
GenomeReviews	Gene locus BLi03971 in contig AE017333_GR. Gene locus BL03923 in contig CP000002_GR.
KEGG	bld:BLi03971. bli:BL03923.
NMPDR	fig|279010.5.peg.4156.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q65DS9.
OMA	ADHHGYV.
Enzyme and pathway databases
BioCyc	BLIC279010:BL03923-MON.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BACLD

Accession

Primary (citable) accession number: Q65DS9
Secondary accession number(s): Q62PA0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	October 25, 2004
Last modified:	November 3, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)