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Protein

Sulfate transporter

Gene

SLC26A2

Organism
Equus caballus (Horse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Sulfate transporter. May play a role in endochondral bone formation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate transporter
Alternative name(s):
Solute carrier family 26 member 2
Gene namesi
Name:SLC26A2
OrganismiEquus caballus (Horse)
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 113CytoplasmicSequence analysisAdd BLAST113
Transmembranei114 – 134HelicalSequence analysisAdd BLAST21
Topological domaini135 – 138ExtracellularSequence analysis4
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 161CytoplasmicSequence analysis2
Transmembranei162 – 182HelicalSequence analysisAdd BLAST21
Topological domaini183 – 218ExtracellularSequence analysisAdd BLAST36
Transmembranei219 – 241HelicalSequence analysisAdd BLAST23
Topological domaini242 – 244CytoplasmicSequence analysis3
Transmembranei245 – 267HelicalSequence analysisAdd BLAST23
Topological domaini268 – 273ExtracellularSequence analysis6
Transmembranei274 – 296HelicalSequence analysisAdd BLAST23
Topological domaini297 – 298CytoplasmicSequence analysis2
Transmembranei299 – 319HelicalSequence analysisAdd BLAST21
Topological domaini320 – 330ExtracellularSequence analysisAdd BLAST11
Transmembranei331 – 351HelicalSequence analysisAdd BLAST21
Topological domaini352 – 379CytoplasmicSequence analysisAdd BLAST28
Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Topological domaini401 – 421ExtracellularSequence analysisAdd BLAST21
Transmembranei422 – 442HelicalSequence analysisAdd BLAST21
Topological domaini443 – 456CytoplasmicSequence analysisAdd BLAST14
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21
Topological domaini478 – 525ExtracellularSequence analysisAdd BLAST48
Transmembranei526 – 546HelicalSequence analysisAdd BLAST21
Topological domaini547 – 736CytoplasmicSequence analysisAdd BLAST190

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_50000726381 – 736Sulfate transporterAdd BLAST736

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei12PhosphoserineBy similarity1
Modified residuei16PhosphoserineBy similarity1
Glycosylationi201N-linked (GlcNAc...)Sequence analysis1
Glycosylationi207N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ65AC2.
PRIDEiQ65AC2.

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000020821.

Structurei

3D structure databases

ProteinModelPortaliQ65AC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini570 – 721STASPROSITE-ProRule annotationAdd BLAST152

Sequence similaritiesi

Contains 1 STAS domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0236. Eukaryota.
COG0659. LUCA.
HOGENOMiHOG000006546.
InParanoidiQ65AC2.
KOiK14701.

Family and domain databases

Gene3Di3.30.750.24. 2 hits.
InterProiIPR018045. S04_transporter_CS.
IPR011547. SLC26A/SulP_dom.
IPR001902. SLC26A/SulP_fam.
IPR030280. SLC26A2.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR11814. PTHR11814. 3 hits.
PTHR11814:SF16. PTHR11814:SF16. 3 hits.
PfamiPF01740. STAS. 1 hit.
PF00916. Sulfate_transp. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 2 hits.
TIGRFAMsiTIGR00815. sulP. 1 hit.
PROSITEiPS01130. SLC26A. 1 hit.
PS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q65AC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSESKEPHV LSPKDSFEGN DRYSPPSRIH LELEKKSSTD FKQFEASEPC
60 70 80 90 100
RPYPRIHMEP QEKSNTNFKQ FVIKKLQKSC QCSPTKAKNM IFGFLPVLQW
110 120 130 140 150
LPKYDLKKNI LGDVMSGLIV GILLVPQSIA YSLLAGQEPI YGLYTSFFAS
160 170 180 190 200
LIYFLLGTSR HISVGIFGVL CLMIGEVVDR ELLKAGYDTV HIAPSLGMVS
210 220 230 240 250
NGSTSLNQTS DRICDRSCYA IKVGSTVTFL AGIYQVAMGF FQVGFVSVYL
260 270 280 290 300
SDALLSGFVT GASFTILTSQ AKYLLGLSLP RSSGVGSLIT TWIHIFRNIH
310 320 330 340 350
KTNVCDLITS LLCLLVLLPT KELNEHFKSK LKAPIPTELV VVVAATLASH
360 370 380 390 400
FGKLHEKYNT SIAGHIPTGF MPPKAPDWNL IPSVAVDAIA ISIIGFAITV
410 420 430 440 450
SLSEMFAKKH GYTVKANQEM YAIGFCNIIP SFFHCFTTSA ALAKTLVKES
460 470 480 490 500
TGCQSQLSGV MTALVLLLVL LVIAPLFYSL QKSVLGVITI VNLRGALRKF
510 520 530 540 550
RDLPKMWRVS RMDTVIWFVT MLSSALISTE LGLLIGVCFS MFCVILRTQK
560 570 580 590 600
PKVSLLGLVE ETEIFESMSA YKNLQARPGI KIFRFVAPLY YINKECFKSA
610 620 630 640 650
LYKKTLNPVL VKAAQKKAAK RKIKKQPVTL SGIQNEISVQ LSHDPLELRT
660 670 680 690 700
IVIDCSAIQF LDTAGIHTLK EVRRDYEAIG IQVLLAQCNP SVRDSLARGE
710 720 730
YCKDEEENLL FYSVYEAMAF AEESQNQKGI CIPNGL
Length:736
Mass (Da):81,489
Last modified:October 25, 2004 - v1
Checksum:iCB81CA27F63B940F
GO

Sequence cautioni

The sequence CAG27693 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ698508 mRNA. Translation: CAG27404.1.
AJ698728 Genomic DNA. Translation: CAG27563.1.
AJ698944 Genomic DNA. Translation: CAG27693.1. Sequence problems.
RefSeqiNP_001075403.1. NM_001081934.2.
UniGeneiEca.12728.

Genome annotation databases

GeneIDi100034141.
KEGGiecb:100034141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ698508 mRNA. Translation: CAG27404.1.
AJ698728 Genomic DNA. Translation: CAG27563.1.
AJ698944 Genomic DNA. Translation: CAG27693.1. Sequence problems.
RefSeqiNP_001075403.1. NM_001081934.2.
UniGeneiEca.12728.

3D structure databases

ProteinModelPortaliQ65AC2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000020821.

Proteomic databases

PaxDbiQ65AC2.
PRIDEiQ65AC2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100034141.
KEGGiecb:100034141.

Organism-specific databases

CTDi1836.

Phylogenomic databases

eggNOGiKOG0236. Eukaryota.
COG0659. LUCA.
HOGENOMiHOG000006546.
InParanoidiQ65AC2.
KOiK14701.

Family and domain databases

Gene3Di3.30.750.24. 2 hits.
InterProiIPR018045. S04_transporter_CS.
IPR011547. SLC26A/SulP_dom.
IPR001902. SLC26A/SulP_fam.
IPR030280. SLC26A2.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR11814. PTHR11814. 3 hits.
PTHR11814:SF16. PTHR11814:SF16. 3 hits.
PfamiPF01740. STAS. 1 hit.
PF00916. Sulfate_transp. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 2 hits.
TIGRFAMsiTIGR00815. sulP. 1 hit.
PROSITEiPS01130. SLC26A. 1 hit.
PS50801. STAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS26A2_HORSE
AccessioniPrimary (citable) accession number: Q65AC2
Secondary accession number(s): Q4W444
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: October 25, 2004
Last modified: July 6, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.