Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sulfate transporter

Gene

SLC26A2

Organism
Equus caballus (Horse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Sulfate transporter. May play a role in endochondral bone formation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate transporter
Alternative name(s):
Solute carrier family 26 member 2
Gene namesi
Name:SLC26A2
OrganismiEquus caballus (Horse)
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 113113CytoplasmicSequence analysisAdd
BLAST
Transmembranei114 – 13421HelicalSequence analysisAdd
BLAST
Topological domaini135 – 1384ExtracellularSequence analysis
Transmembranei139 – 15921HelicalSequence analysisAdd
BLAST
Topological domaini160 – 1612CytoplasmicSequence analysis
Transmembranei162 – 18221HelicalSequence analysisAdd
BLAST
Topological domaini183 – 21836ExtracellularSequence analysisAdd
BLAST
Transmembranei219 – 24123HelicalSequence analysisAdd
BLAST
Topological domaini242 – 2443CytoplasmicSequence analysis
Transmembranei245 – 26723HelicalSequence analysisAdd
BLAST
Topological domaini268 – 2736ExtracellularSequence analysis
Transmembranei274 – 29623HelicalSequence analysisAdd
BLAST
Topological domaini297 – 2982CytoplasmicSequence analysis
Transmembranei299 – 31921HelicalSequence analysisAdd
BLAST
Topological domaini320 – 33011ExtracellularSequence analysisAdd
BLAST
Transmembranei331 – 35121HelicalSequence analysisAdd
BLAST
Topological domaini352 – 37928CytoplasmicSequence analysisAdd
BLAST
Transmembranei380 – 40021HelicalSequence analysisAdd
BLAST
Topological domaini401 – 42121ExtracellularSequence analysisAdd
BLAST
Transmembranei422 – 44221HelicalSequence analysisAdd
BLAST
Topological domaini443 – 45614CytoplasmicSequence analysisAdd
BLAST
Transmembranei457 – 47721HelicalSequence analysisAdd
BLAST
Topological domaini478 – 52548ExtracellularSequence analysisAdd
BLAST
Transmembranei526 – 54621HelicalSequence analysisAdd
BLAST
Topological domaini547 – 736190CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 736736Sulfate transporterPRO_5000072638Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei12 – 121PhosphoserineBy similarity
Modified residuei16 – 161PhosphoserineBy similarity
Glycosylationi201 – 2011N-linked (GlcNAc...)Sequence analysis
Glycosylationi207 – 2071N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ65AC2.
PRIDEiQ65AC2.

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000020821.

Structurei

3D structure databases

ProteinModelPortaliQ65AC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini570 – 721152STASPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 STAS domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0236. Eukaryota.
COG0659. LUCA.
HOGENOMiHOG000006546.
InParanoidiQ65AC2.
KOiK14701.

Family and domain databases

Gene3Di3.30.750.24. 2 hits.
InterProiIPR018045. S04_transporter_CS.
IPR011547. SLC26A/SulP_dom.
IPR001902. SLC26A/SulP_fam.
IPR030280. SLC26A2.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR11814. PTHR11814. 3 hits.
PTHR11814:SF16. PTHR11814:SF16. 3 hits.
PfamiPF01740. STAS. 1 hit.
PF00916. Sulfate_transp. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 2 hits.
TIGRFAMsiTIGR00815. sulP. 1 hit.
PROSITEiPS01130. SLC26A. 1 hit.
PS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q65AC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSESKEPHV LSPKDSFEGN DRYSPPSRIH LELEKKSSTD FKQFEASEPC
60 70 80 90 100
RPYPRIHMEP QEKSNTNFKQ FVIKKLQKSC QCSPTKAKNM IFGFLPVLQW
110 120 130 140 150
LPKYDLKKNI LGDVMSGLIV GILLVPQSIA YSLLAGQEPI YGLYTSFFAS
160 170 180 190 200
LIYFLLGTSR HISVGIFGVL CLMIGEVVDR ELLKAGYDTV HIAPSLGMVS
210 220 230 240 250
NGSTSLNQTS DRICDRSCYA IKVGSTVTFL AGIYQVAMGF FQVGFVSVYL
260 270 280 290 300
SDALLSGFVT GASFTILTSQ AKYLLGLSLP RSSGVGSLIT TWIHIFRNIH
310 320 330 340 350
KTNVCDLITS LLCLLVLLPT KELNEHFKSK LKAPIPTELV VVVAATLASH
360 370 380 390 400
FGKLHEKYNT SIAGHIPTGF MPPKAPDWNL IPSVAVDAIA ISIIGFAITV
410 420 430 440 450
SLSEMFAKKH GYTVKANQEM YAIGFCNIIP SFFHCFTTSA ALAKTLVKES
460 470 480 490 500
TGCQSQLSGV MTALVLLLVL LVIAPLFYSL QKSVLGVITI VNLRGALRKF
510 520 530 540 550
RDLPKMWRVS RMDTVIWFVT MLSSALISTE LGLLIGVCFS MFCVILRTQK
560 570 580 590 600
PKVSLLGLVE ETEIFESMSA YKNLQARPGI KIFRFVAPLY YINKECFKSA
610 620 630 640 650
LYKKTLNPVL VKAAQKKAAK RKIKKQPVTL SGIQNEISVQ LSHDPLELRT
660 670 680 690 700
IVIDCSAIQF LDTAGIHTLK EVRRDYEAIG IQVLLAQCNP SVRDSLARGE
710 720 730
YCKDEEENLL FYSVYEAMAF AEESQNQKGI CIPNGL
Length:736
Mass (Da):81,489
Last modified:October 25, 2004 - v1
Checksum:iCB81CA27F63B940F
GO

Sequence cautioni

The sequence CAG27693.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ698508 mRNA. Translation: CAG27404.1.
AJ698728 Genomic DNA. Translation: CAG27563.1.
AJ698944 Genomic DNA. Translation: CAG27693.1. Sequence problems.
RefSeqiNP_001075403.1. NM_001081934.2.
UniGeneiEca.12728.

Genome annotation databases

GeneIDi100034141.
KEGGiecb:100034141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ698508 mRNA. Translation: CAG27404.1.
AJ698728 Genomic DNA. Translation: CAG27563.1.
AJ698944 Genomic DNA. Translation: CAG27693.1. Sequence problems.
RefSeqiNP_001075403.1. NM_001081934.2.
UniGeneiEca.12728.

3D structure databases

ProteinModelPortaliQ65AC2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000020821.

Proteomic databases

PaxDbiQ65AC2.
PRIDEiQ65AC2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100034141.
KEGGiecb:100034141.

Organism-specific databases

CTDi1836.

Phylogenomic databases

eggNOGiKOG0236. Eukaryota.
COG0659. LUCA.
HOGENOMiHOG000006546.
InParanoidiQ65AC2.
KOiK14701.

Family and domain databases

Gene3Di3.30.750.24. 2 hits.
InterProiIPR018045. S04_transporter_CS.
IPR011547. SLC26A/SulP_dom.
IPR001902. SLC26A/SulP_fam.
IPR030280. SLC26A2.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR11814. PTHR11814. 3 hits.
PTHR11814:SF16. PTHR11814:SF16. 3 hits.
PfamiPF01740. STAS. 1 hit.
PF00916. Sulfate_transp. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 2 hits.
TIGRFAMsiTIGR00815. sulP. 1 hit.
PROSITEiPS01130. SLC26A. 1 hit.
PS50801. STAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Assignment of the equine solute carrier 26A2 gene (SLC26A2) to equine chromosome 14q15-->q21 (ECA14q15-->q21) by in situ hybridization and radiation hybrid panel mapping."
    Brenig B., Beck J., Hall A.J., Broad T.E., Chowdhary B.P., Piumi F.
    Cytogenet. Genome Res. 107:139-139(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].

Entry informationi

Entry nameiS26A2_HORSE
AccessioniPrimary (citable) accession number: Q65AC2
Secondary accession number(s): Q4W444
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: October 25, 2004
Last modified: February 17, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.