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Protein
Submitted name:

Putative uncharacterized protein DKFZp666O0110

Gene

DKFZp666O0110

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein DKFZp666O0110Imported
Gene namesi
Name:DKFZp666O0110Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33955.

PTM / Processingi

Proteomic databases

PaxDbiQ658W2.
PeptideAtlasiQ658W2.
PRIDEiQ658W2.

PTM databases

iPTMnetiQ658W2.

Miscellaneous databases

PMAP-CutDBQ658W2.

Expressioni

Gene expression databases

GenevisibleiQ658W2. HS.

Interactioni

Protein-protein interaction databases

MINTiMINT-1434802.
STRINGi9606.ENSP00000341189.

Structurei

3D structure databases

ProteinModelPortaliQ658W2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 377321FERMInterPro annotationAdd
BLAST
Domaini444 – 702259Protein kinaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG4257. Eukaryota.
ENOG410ZH9Y. LUCA.
HOGENOMiHOG000069938.
HOVERGENiHBG004018.
KOiK05725.

Family and domain databases

InterProiIPR019749. Band_41_domain.
IPR019748. FERM_central.
IPR000299. FERM_domain.
IPR005189. Focal_adhesion_kin_target_dom.
IPR011009. Kinase-like_dom.
IPR011993. PH_dom-like.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00373. FERM_M. 1 hit.
PF03623. Focal_AT. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
ProDomiPD006413. Focal_adhesion_target_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00295. B41. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF54236. SSF54236. 1 hit.
SSF56112. SSF56112. 1 hit.
SSF68993. SSF68993. 1 hit.
PROSITEiPS50057. FERM_3. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q658W2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISADCNLCL PEYDRYLASS KIMAAAYLDP NLNHTPNSST KTHLGTGMER
60 70 80 90 100
SPGAMERVLK VFHYFESNSE PTTWASIIRH GDATDVRGII QKIVDSHKVK
110 120 130 140 150
HVACYGFRLS HLRSEEVHWL HVDMGVSSVR EKYELAHPPE EWKYELRIRY
160 170 180 190 200
LPKGFLNQFT EDKPTLNFFY QQVKSDYMLE IADQVDQEIA LKLGCLEIRR
210 220 230 240 250
SYWEMRGNAL EKKSNYEVLE KDVGLKRFFP KSLLDSVKAK TLRKLIQQTF
260 270 280 290 300
RQFANLNREE SILKFFEILS PVYRFDKECF KCALGSSWII SVELAIGPEE
310 320 330 340 350
GISYLTDKGC NPTHLADFTQ VQTIQYSNSE DKDRKGMLQL KIAGAPEPLT
360 370 380 390 400
VTAPSLTIAE NMADLIDGYC RLVNGTSQSF IIRPQKEGER ALPSIPKLAN
410 420 430 440 450
SEKQGMRTHA VSVSETDDYA EIIDEEDTYT MPSTRDYEIQ RERIELGRCI
460 470 480 490 500
GEGQFGDVHQ GIYMSPENPA LAVAIKTCKN CTSDSVREKF LQEALTMRQF
510 520 530 540 550
DHPHIVKLIG VITENPVWII MELCTLGELR SFLQVRKYSL DLASLILYAY
560 570 580 590 600
QLSTALAYLE SKRFVHRDIA ARNVLVSSND CVKLGDFGLS RYMEDSTYYK
610 620 630 640 650
ASKGKLPIKW MAPESINFRR FTSASDVWMF GVCMWEILMH GVKPFQGVKN
660 670 680 690 700
NDVIGRIENG ERLPMPPNCP PTLYSLMTKC WAYDPSRRPR FTELKAQLST
710 720 730 740 750
ILEEEKAQQE ERMRMESRRQ ATVSWDSGGS DEAPPKPSRP GYPSPRSSEG
760 770 780 790 800
FYPSPQHMVQ TNHYQVSGYP GSHGITAMAG SIYPGQASLL DQTDSWNHRP
810 820 830 840 850
QEIAMWQPNV EDSTVLDLRG IGQVLPTHLM EERLIRQQQE MEEDQRWLEK
860 870 880 890 900
EERFLKPDVR LSRGSIDRED GSLQGPIGNQ HIYQPVGKPD PAAPPKKPPR
910 920 930 940 950
PGAPGHLGSL ASLSSPADSY NEGVKLQPQE ISPPPTANLD RSNDKVYENV
960 970 980 990 1000
TGLVKAVIEM SSKIQPAPPE EYVPMVKEVG LALRTLLATV DETIPLLPAS
1010 1020 1030 1040 1050
THREIEMAQK LLNSDLGELI NKMKLAQQYV MTSLQQEYKK QMLTAAHALA
1060 1070
VDAKNLLDVI DQARLKMLGQ TRPH
Length:1,074
Mass (Da):121,721
Last modified:October 25, 2004 - v1
Checksum:i49E165262172ADE7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL832961 mRNA. Translation: CAH56296.1.
RefSeqiNP_001186578.1. NM_001199649.1.
NP_005598.3. NM_005607.4.
NP_722560.1. NM_153831.3.
UniGeneiHs.395482.

Genome annotation databases

GeneIDi5747.
KEGGihsa:5747.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL832961 mRNA. Translation: CAH56296.1.
RefSeqiNP_001186578.1. NM_001199649.1.
NP_005598.3. NM_005607.4.
NP_722560.1. NM_153831.3.
UniGeneiHs.395482.

3D structure databases

ProteinModelPortaliQ658W2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1434802.
STRINGi9606.ENSP00000341189.

PTM databases

iPTMnetiQ658W2.

Proteomic databases

PaxDbiQ658W2.
PeptideAtlasiQ658W2.
PRIDEiQ658W2.

Protocols and materials databases

DNASUi5747.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5747.
KEGGihsa:5747.

Organism-specific databases

CTDi5747.
PharmGKBiPA33955.

Phylogenomic databases

eggNOGiKOG4257. Eukaryota.
ENOG410ZH9Y. LUCA.
HOGENOMiHOG000069938.
HOVERGENiHBG004018.
KOiK05725.

Miscellaneous databases

GenomeRNAii5747.
PMAP-CutDBQ658W2.

Gene expression databases

GenevisibleiQ658W2. HS.

Family and domain databases

InterProiIPR019749. Band_41_domain.
IPR019748. FERM_central.
IPR000299. FERM_domain.
IPR005189. Focal_adhesion_kin_target_dom.
IPR011009. Kinase-like_dom.
IPR011993. PH_dom-like.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00373. FERM_M. 1 hit.
PF03623. Focal_AT. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
ProDomiPD006413. Focal_adhesion_target_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00295. B41. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF54236. SSF54236. 1 hit.
SSF56112. SSF56112. 1 hit.
SSF68993. SSF68993. 1 hit.
PROSITEiPS50057. FERM_3. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ658W2_HUMAN
AccessioniPrimary (citable) accession number: Q658W2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: July 6, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.