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Protein
Submitted name:

Down-regulator of transcription 1, TBP-binding (Negative cofactor 2), isoform CRA_a

Gene

DKFZp666G145

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Down-regulator of transcription 1, TBP-binding (Negative cofactor 2), isoform CRA_aImported
Submitted name:
cDNA FLJ32979 fis, clone TESTI2017775, highly similar to TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEINImported
Gene namesi
Name:DKFZp666G145Imported
Synonyms:DR1Imported
ORF Names:hCG_31940Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000117505.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27475

Expressioni

Gene expression databases

BgeeiENSG00000117505

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 75CBFD_NFYB_HMFInterPro annotationAdd BLAST64

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili115 – 139Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0871 Eukaryota
COG5150 LUCA
HOVERGENiHBG002051
KOiK21751
OMAiTIACDHI
OrthoDBiEOG091G0ZDR

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR003958 CBFA_NFYB_domain
IPR009072 Histone-fold
PfamiView protein in Pfam
PF00808 CBFD_NFYB_HMF, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit

Sequencei

Sequence statusi: Complete.

Q658N3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI
60 70 80 90 100
SSEANEICNK SEKKTISPEH VIQALESLGF GSYISEVKEV LQECKTVALK
110 120 130 140 150
RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WLQMQQAAQQ
160 170
AQLAAASASA SNQAGSSQDE EDDDDI
Length:176
Mass (Da):19,444
Last modified:May 10, 2005 - v1
Checksum:i36E7E59F2FD6CAB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057541 mRNA Translation: BAG51931.1
AL833729 mRNA Translation: CAH56250.1
CH471097 Genomic DNA Translation: EAW73072.1
CH471097 Genomic DNA Translation: EAW73073.1
CH471097 Genomic DNA Translation: EAW73074.1
CH471097 Genomic DNA Translation: EAW73075.1
CH471097 Genomic DNA Translation: EAW73076.1
RefSeqiNP_001929.1, NM_001938.2
UniGeneiHs.348418

Genome annotation databases

GeneIDi1810
KEGGihsa:1810
UCSCiuc001dpu.4 human

Similar proteinsi

Entry informationi

Entry nameiQ658N3_HUMAN
AccessioniPrimary (citable) accession number: Q658N3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 25, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health