Q658L1 (F154B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein FAM154B

Gene names

Name:

FAM154B

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the FAM154 family.
Caution	It is uncertain whether Met-1 or Met-6 is the initiator.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 398	398	Protein FAM154B		PRO_0000321839
Natural variations
	Natural variant	8	1	S → G. Corresponds to variant rs11631813 [ dbSNP | Ensembl ].		VAR_039359
	Natural variant	34	1	P → L. Corresponds to variant rs16973457 [ dbSNP | Ensembl ].		VAR_039360
	Natural variant	225	1	W → R. Corresponds to variant rs11630197 [ dbSNP | Ensembl ].		VAR_039361

Sequences

	Sequence		Length	Mass (Da)
	Q658L1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 3A140F0C31B065C8	FASTA	398	45,933
	10 20 30 40 50 60 MGAKSMRSWC LCQICSCGSD YCPYEIVKQP RHVPEEYKPK QGKIDLGTTY KRDLNSYKVQ 70 80 90 100 110 120 PVAIVRPLER QVKKGKLDTV PTYKDDYRAW DLHKSELYKP EQTYHPPTVK FGNSTTFQDD 130 140 150 160 170 180 FVPQEIKPRQ SFKPSSVVKR STAPFNGITS HRLDYIPHQL ELKFERPKEV YKPTDQRFED 190 200 210 220 230 240 LTTHRCDFQG LIGETAKLCR PVHTRVTQNA LFEGSTEFRE SFQPWEIPPP EVKKVPEYVP 250 260 270 280 290 300 PTGSMLLNST SHLDYVPYQA NHVVPIRPVS QKRSNNFPFQ GKSIMKEDFP AWESCRQGLI 310 320 330 340 350 360 KKQQQIPNPS GKFDGLSTFR SHYVPHELIP TESCKPLNIA FKSSVPFDDV TMYSVEYTPK 370 380 390 RQEICPASYP SPPGYIFDNT NSQGHKFFRK IIPAVKAF

References

[1]

"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Stomach.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL833762 mRNA. Translation: CAH56241.1.
IPI	IPI00176938.
RefSeq	NP_001008227.1. NM_001008226.1.
UniGene	Hs.459117.
3D structure databases
ProteinModelPortal	Q658L1.
ModBase	Search...
PTM databases
PhosphoSite	Q658L1.
Polymorphism databases
DMDM	74708419.
Proteomic databases
PaxDb	Q658L1.
PRIDE	Q658L1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000339465; ENSP00000340445; ENSG00000188659.
GeneID	283726.
KEGG	hsa:283726.
UCSC	uc002bgv.3. human.
Organism-specific databases
CTD	283726.
GeneCards	GC15P082555.
H-InvDB	HIX0012504.
HGNC	HGNC:33727. FAM154B.
HPA	HPA040487. HPA040833.
neXtProt	NX_Q658L1.
PharmGKB	PA162386665.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG87688.
HOGENOM	HOG000049249.
HOVERGEN	HBG060301.
InParanoid	Q658L1.
OMA	PWEIPPP.
OrthoDB	EOG4NCMCV.
Gene expression databases
ArrayExpress	Q658L1.
Bgee	Q658L1.
CleanEx	HS_FAM154B.
Genevestigator	Q658L1.
Family and domain databases
InterPro	IPR024963. STOP/FAM154. [Graphical view]
Pfam	PF05217. STOP. 3 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	283726.
NextBio	94199.

Entry information

Entry name

F154B_HUMAN

Accession

Primary (citable) accession number: Q658L1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	October 25, 2004
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.