ID   PAP1_ASFB7              Reviewed;         475 AA.
AC   Q65159;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   08-NOV-2023, entry version 69.
DE   RecName: Full=Putative poly(A) polymerase catalytic subunit {ECO:0000303|PubMed:23041356};
DE            EC=2.7.7.19;
GN   OrderedLocusNames=Ba71V-067; ORFNames=C475L;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus; African swine fever virus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   REVIEW.
RX   PubMed=23041356; DOI=10.1016/j.virusres.2012.09.014;
RA   Rodriguez J.M., Salas M.L.;
RT   "African swine fever virus transcription.";
RL   Virus Res. 173:15-28(2013).
RN   [3]
RP   SUBCELLULAR LOCATION.
RX   PubMed=30185597; DOI=10.1128/jvi.01293-18;
RA   Alejo A., Matamoros T., Guerra M., Andres G.;
RT   "A Proteomic Atlas of the African Swine Fever Virus Particle.";
RL   J. Virol. 92:0-0(2018).
RN   [4]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Polymerase that creates the 3'-poly(A) tail of mRNA's.
CC       {ECO:0000305}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide;
CC         Xref=Rhea:RHEA:11332, Rhea:RHEA-COMP:14527, Rhea:RHEA-COMP:17347,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:140395,
CC         ChEBI:CHEBI:173115; EC=2.7.7.19;
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:30185597}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the poxviridae poly(A) polymerase catalytic
CC       subunit family. Highly divergent. {ECO:0000305}.
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DR   EMBL; U18466; AAA65297.1; -; Genomic_DNA.
DR   RefSeq; NP_042761.1; NC_001659.2.
DR   SMR; Q65159; -.
DR   GeneID; 22220297; -.
DR   KEGG; vg:22220297; -.
DR   Proteomes; UP000000624; Segment.
DR   GO; GO:0044423; C:virion component; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   CDD; cd20924; polyA_pol_Asfar; 1.
DR   InterPro; IPR045355; PolyA_pol_cat_su.
DR   Pfam; PF19244; Poly_A_pol_cat; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Late protein; mRNA processing; Nucleotide-binding;
KW   Reference proteome; Transcription; Transferase; Virion.
FT   CHAIN           1..475
FT                   /note="Putative poly(A) polymerase catalytic subunit"
FT                   /id="PRO_0000308944"
SQ   SEQUENCE   475 AA;  54764 MW;  A295B0A213AB9442 CRC64;
     MSSLLKTDFN VSKYRLIAQK REANAVEIEA ALEVVREFII KKKLILYGGI AIDYALHLKG
     SSIYPEGERP DFDMFSPNHV EDAYELADIL YEKGFKQVGT VRAIHVQTMR VRTDFVWVAD
     LSYMPPNIFN TIPTLTYKNL KIIHPDYQRA GLHLAFCFPF DNPPREDVFS RFKKDLQRYN
     LIEKYYPIPV VPVKSIYESK TFSIPFKQVA IHGFAAYALL YQTLNELRIT CKVPEWKTEF
     PQPSYSYHKN DKNITLTVDM PKAYPALVLA TYNPEEVIKE MGLHLTEICE PYMDYSPPIF
     KTNDIHFFST MFKELAISII QDNLIVVSPQ YLLLYFLYGA FATPADKSLF LFYYNATLWI
     LEKADSLLNI IQKQTSPEEF TRFANTSPFV LTTRVLSCSQ ERCTFSPAYR ISLANDVQQS
     QLPLPKTHFL SNSLPDVSTL PYNYYPGKGK DRPTNFSYEK NLLFNIGGKC TPSAM
//