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Q64Z48 (ACKA_BACFR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BF0479
OrganismBacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]
Taxonomic identifier295405 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Acetate kinase HAMAP MF_00020
PRO_0000107529

Sequences

Sequence LengthMass (Da)Tools
Q64Z48 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 6DE0C4B55787E457

FASTA39843,028
        10         20         30         40         50         60 
MKVLVLNCGS SSIKYKLFDM DSKEVIAQGG IEKIGLKDSF LKLTLPNGEK KILEKDIPEH 

        70         80         90        100        110        120 
TVGVEFILNT LVSPEYGAIQ SLEEINAVGH RMVHGGERFS KSVLLTKEVL EAFAACNDLA 

       130        140        150        160        170        180 
PLHNPANLKG VDAITAILPN VPQIGVFDTA FHQTMPEHAY LYAIPYELYK KYGVRRYGFH 

       190        200        210        220        230        240 
GTSHRYVSQR VCEYLGIKPE GLKLITCHIG NGGSIAAIKD GKCIDTSMGL TPLEGLMMGT 

       250        260        270        280        290        300 
RSGDIDAGAV TFIMDKEGLT TTGISNLLNK KSGVAGMMNG SSDMRDLEAA VAKGDPQAIL 

       310        320        330        340        350        360 
TEQMYFYRIK KYIGAYAAAL GGVDVILFTG GVGENQATCR AGVCEGLEFL GVKLDPEKNK 

       370        380        390 
VRGEEAIIST DDSRVKVVVI PTDEELLIAS DTMAILDK

« Hide

References

[1]"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation."
Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.
Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YCH46.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006841 Genomic DNA. Translation: BAD47228.1.
RefSeqYP_097762.1. NC_006347.1.

3D structure databases

ProteinModelPortalQ64Z48.
SMRQ64Z48. Positions 1-398.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3081699.
GenomeReviewsGene locus BF0479 in contig AP006841_GR.
KEGGbfr:BF0479.
PATRIC21046724. VBIBacFra17906_0495.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMALIDMTNE.
PhylomeDBQ64Z48.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycBFRA295405:BF0479-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BACFR
AccessionPrimary (citable) accession number: Q64Z48
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 25, 2004
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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