Reviewed, UniProtKB/Swiss-Prot Q64YG8 (PSD_BACFR)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	BF0711

Organism

Bacteroides fragilis [Complete proteome] [HAMAP]

Taxonomic identifier

817 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity.
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Phosphatidylserine decarboxylase beta chain By similarity		PRO_0000029749
	Chain	197 – 228	32	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_0000029750
Sites
	Site	196 – 197	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	197	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q64YG8-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 962DFD0F60FBD430	FASTA	228	26,017
	10 20 30 40 50 60 MGRLKKLKKI RIHREGTHIL WGSFFLLLII NLALYWGIDC KIPFYLVALV SIVVYLLMVN 70 80 90 100 110 120 FFRCPIRLFG QDTEKIVVAP ADGKIVVIEE VDEHEYFHDR RIMVSIFMSI LNVHANWYPV 130 140 150 160 170 180 DGVVKKVTHD NGKFMKAWLP KASTENERSM IVIETPEGVE VMARQIAGAM ARRIVTYAEP 190 200 210 220 GEECYIDEHL GFIKFGSRVD VYLPLGTEIC VSMGQLTTGN QTVIAKLK

References

[1]

"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y. Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YCH46.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006841 Genomic DNA. Translation: BAD47458.1.
RefSeq	YP_097992.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3082510.
GenomeReviews	Gene locus BF0711 in contig AP006841_GR.
KEGG	bfr:BF0711.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q64YG8.
OMA	DKASEDN.
Enzyme and pathway databases
BioCyc	BFRA295405:BF0711-MON.
BRENDA	4.1.1.65. 868.
Family and domain databases
HAMAP	MF_00664. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase_related. [Graphical view]
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_BACFR

Accession

Primary (citable) accession number: Q64YG8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 2005
Last sequence update:	October 25, 2004
Last modified:	November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)