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Q64YG8 (PSD_BACFR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:BF0711
OrganismBacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]
Taxonomic identifier295405 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length228 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 196196Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029749
Chain197 – 22832Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029750

Sites

Site196 – 1972Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1971Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q64YG8 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 962DFD0F60FBD430

FASTA22826,017
        10         20         30         40         50         60 
MGRLKKLKKI RIHREGTHIL WGSFFLLLII NLALYWGIDC KIPFYLVALV SIVVYLLMVN 

        70         80         90        100        110        120 
FFRCPIRLFG QDTEKIVVAP ADGKIVVIEE VDEHEYFHDR RIMVSIFMSI LNVHANWYPV 

       130        140        150        160        170        180 
DGVVKKVTHD NGKFMKAWLP KASTENERSM IVIETPEGVE VMARQIAGAM ARRIVTYAEP 

       190        200        210        220 
GEECYIDEHL GFIKFGSRVD VYLPLGTEIC VSMGQLTTGN QTVIAKLK

« Hide

References

[1]"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation."
Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.
Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YCH46.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006841 Genomic DNA. Translation: BAD47458.1.
RefSeqYP_097992.1. NC_006347.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3082510.
GenomeReviewsGene locus BF0711 in contig AP006841_GR.
KEGGbfr:BF0711.
PATRIC21047180. VBIBacFra17906_0717.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG541103.
OMANERVVWH.
PhylomeDBQ64YG8.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycBFRA295405:BF0711-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BACFR
AccessionPrimary (citable) accession number: Q64YG8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: October 25, 2004
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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