Q64YA4 (Q64YA4_BACFR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL BAD47522.1

Gene names

Ordered Locus Names:

BF0771

Organism

Bacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]

Taxonomic identifier

295405 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q64YA4 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: CA90CC81F92A00A9	FASTA	377	42,673
	10 20 30 40 50 60 MKYYLIVGEA SGDLHASHLM AALKEEDPEA EFRFFGGDLM AAVGGTMVKH YKELAYMGFI 70 80 90 100 110 120 PVLLHLPTIF ANMKRCKEDI VAWSPDVVIL VDYPGFNLDI AKFVHAKTKI PVYYYISPKI 130 140 150 160 170 180 WAWKEYRIKN IKRDVDELFS ILPFEVGFFK GHRYPIHYVG NPTVDEVTAF KASHQESFAD 190 200 210 220 230 240 FIADSELADK PIIALLAGSR KQEIKDNLPD MIRAASAFPG YQLVLAAAPG ISPEYYAKFV 250 260 270 280 290 300 KGTELAVIFD RTYRLLQQAD VALVTSGTAT LETALFRVPQ VVCYHTPVGK LVSFLRRHIL 310 320 330 340 350 360 KVKFISLVNL IAGREVVREL VADTMTVENM RAELECLLFR EDYRRKMLDG YEEMARLLGP 370 AGAPRHAARE MVKLLKK

References

[1]

"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y. Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YCH46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006841 Genomic DNA. Translation: BAD47522.1.
RefSeq	YP_098056.1. NC_006347.1.
3D structure databases
ProteinModelPortal	Q64YA4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3082988.
GenomeReviews	Gene locus BF0771 in contig AP006841_GR.
KEGG	bfr:BF0771.
PATRIC	21047310. VBIBacFra17906_0781.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK2391382.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q64YA4_BACFR

Accession

Primary (citable) accession number: Q64YA4

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2004
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)