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Q64WA0 (Q64WA0_BACFR) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Ordered Locus Names:BF1475
OrganismBacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]
Taxonomic identifier295405 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q64WA0 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 6257D2C0E779E0CF

FASTA36939,703
        10         20         30         40         50         60 
MIIGVPKEIK NNENRVGMTP SGVAELVKRG HTVYIQHTAG ENSGFQDEAY TAVGAQILPT 

        70         80         90        100        110        120 
MEETYAMAQM IVKVKEPIAP EYRLIRKGQL LFTYFHFASD RELTLAMIEN GSVCLAYETV 

       130        140        150        160        170        180 
EKADHSLPLL IPMSEVAGRM AIQEGARFLE KPQGGKGILP GGVPGVKPAK VLILGGGIVG 

       190        200        210        220        230        240 
SNAAQMAAGL GADVTIADIN LSRLRYLSET LPKNVKTLYA SEVRLKKELP DVDLVVGSVL 

       250        260        270        280        290        300 
IPGDKAPHLI TRDMLKMMQP GTVLVDVAID QGGCFETSHP TTHSEPTYVV DGIVHYAVAN 

       310        320        330        340        350        360 
IPGAVPYTST LALTNATLPY VIALANKGWR KACKEDPALA LGLNVVEGKV VYRAIADVFG 


LKYEQLNLE

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References

[1]"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation."
Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.
Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YCH46.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006841 Genomic DNA. Translation: BAD48226.1.
RefSeqYP_098760.1. NC_006347.1.

3D structure databases

ProteinModelPortalQ64WA0.
SMRQ64WA0. Positions 1-360.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3082276.
GenomeReviewsGene locus BF1475 in contig AP006841_GR.
KEGGbfr:BF1475.
PATRIC21048643. VBIBacFra17906_1439.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG289735.
OMAVAHGHEV.
PhylomeDBQ64WA0.
ProtClustDBCLSK822772.

Family and domain databases

InterProIPR008142. Ala_DH/PNT_CS1.
IPR008143. Ala_DH/PNT_CS2.
IPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
PROSITEPS00836. ALADH_PNT_1. 1 hit.
PS00837. ALADH_PNT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ64WA0_BACFR
AccessionPrimary (citable) accession number: Q64WA0
Entry history
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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