Q64VR0 (CYSD_BACFR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	BF1668

Organism

Bacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]

Taxonomic identifier

295405 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340178

Sequences

	Sequence		Length	Mass (Da)
	Q64VR0 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: AAD7CD766089EC19	FASTA	303	35,840
	10 20 30 40 50 60 MKEEYKLSHL KELEAESIHI IREVAAEFEN PVMLYSIGKD SSVMVRLAEK AFYPGKVPFP 70 80 90 100 110 120 LMHIDSKWKF KEMIQFRDEY AKKYGWNLIV ESNMEAFHAG VGPFTHGSKV HTDLMKTQAL 130 140 150 160 170 180 LRALDKYKFD AAFGGARRDE EKSRAKERIF SFRDKFHQWD PKNQRPELWD IYNARVHKGE 190 200 210 220 230 240 SIRVFPLSNW TELDIWQYIR LENIPIVPLY YAKERPVVQM DGNLIMADDE RLPEKYRDQI 250 260 270 280 290 300 EMKMVRFRTL GCWPLTGAVE SEADTIEKIV EEMMTTTKSE RTTRVIDFDQ EGSMEQKKRE GYF

References

[1]

"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y. Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YCH46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006841 Genomic DNA. Translation: BAD48416.1.
RefSeq	YP_098950.1. NC_006347.1.
3D structure databases
HSSP	HSSP built from PDB template 1ZUN based on UniProtKB Q87WW0.
ProteinModelPortal	Q64VR0.
SMR	Q64VR0. Positions 6-212.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3082329.
GenomeReviews	Gene locus BF1668 in contig AP006841_GR.
KEGG	bfr:BF1668.
PATRIC	21049003. VBIBacFra17906_1619.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG758022.
OMA	HRWDPRN.
PhylomeDB	Q64VR0.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	BFRA295405:BF1668-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_BACFR

Accession

Primary (citable) accession number: Q64VR0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program