Q64TJ9 (GCP_BACFR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BF2431

Organism

Bacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]

Taxonomic identifier

295405 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	339 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 339	339	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303271

Sequences

	Sequence		Length	Mass (Da)
	Q64TJ9 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: F7521CDA5B140350	FASTA	339	36,956
	10 20 30 40 50 60 MSTIILGIES SCDDTSAAVI KDGYLLSNVV SSQAVHEAYG GVVPELASRA HQQNIVPVVH 70 80 90 100 110 120 EALKRAGVTK EELSAVAFTR GPGLMGSLLV GVSFAKGFAR SLNIPMIDVN HLTGHVLAHF 130 140 150 160 170 180 IKEEGEANEQ PDFPFLCLLV SGGNSQIILV KAYNDMEILG QTIDDAAGEA IDKCSKVMGL 190 200 210 220 230 240 GYPGGPIIDR LARQGNPKAY TFSKPHISGL DYSFSGLKTS FLYSLRDWMK EDPDFIEHHK 250 260 270 280 290 300 NDLAASLEAT VVDILMDKLR KAAKQYKINE VAVAGGVSAN NGLRNAFREH AEKYGWKIFI 310 320 330 PKFSYTTDNA AMIAITGYFK YQDKDFCSIE QPAYSRVTL

References

[1]

"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y. Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YCH46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006841 Genomic DNA. Translation: BAD49180.1.
RefSeq	YP_099714.1. NC_006347.1.
3D structure databases
ProteinModelPortal	Q64TJ9.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3083908.
GenomeReviews	Gene locus BF2431 in contig AP006841_GR.
KEGG	bfr:BF2431.
PATRIC	21050491. VBIBacFra17906_2349.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	MEVIGQT.
PhylomeDB	Q64TJ9.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BFRA295405:BF2431-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BACFR

Accession

Primary (citable) accession number: Q64TJ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program