Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribonucleoside-diphosphate reductase subunit beta

Gene

BF2694

Organism
Bacteroides fragilis (strain YCH46)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.UniRule annotation

Catalytic activityi

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.UniRule annotation

Cofactori

Fe cationUniRule annotationNote: Binds 2 iron ions per subunit.UniRule annotation

Pathway: DNA replication

This protein is involved in the pathway DNA replication, which is part of Genetic information processing.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway DNA replication and in Genetic information processing.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

DNA replicationUniRule annotation

Keywords - Ligandi

IronUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00326.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleoside-diphosphate reductase subunit betaUniRule annotation (EC:1.17.4.1UniRule annotation)
Gene namesi
Ordered Locus Names:BF2694Imported
OrganismiBacteroides fragilis (strain YCH46)Imported
Taxonomic identifieri295405 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000002197 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliQ64ST5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribonucleoside diphosphate reductase small chain family.UniRule annotation

Phylogenomic databases

KOiK00526.
OMAiHWNKLKA.
OrthoDBiEOG6J48J7.

Family and domain databases

Gene3Di1.10.620.20. 1 hit.
InterProiIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR000358. RNR_small.
IPR030475. RNR_small_AS.
[Graphical view]
PANTHERiPTHR23409. PTHR23409. 1 hit.
PfamiPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFiPIRSF000355. NrdB. 1 hit.
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00368. RIBORED_SMALL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q64ST5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKKLKKNA LFNPEGDTET RLRKMIGGNT TNLNDFNNMR YKWVSDWYRQ
60 70 80 90 100
GMNNFWIPEE INLTQDTKDY PHLTPAERTA YDKILSFLVF LDSLQSNNLP
110 120 130 140 150
TLSEYITANE VNLCLHIQAF QECVHSQSYS YMLDSICSPE ERNDILYQWK
160 170 180 190 200
TDEHLLRRNT FIGNCYNEFQ ENRDGFALMK TLIANYILEG IYFYSGFMFF
210 220 230 240 250
YNLSRNGKMS GSAQEIRYIN RDENTHLWLF RNIILELKKE EPELFTPDKV
260 270 280 290 300
KVYEEMMREG VKQEIAWGQY VIGDQIQGLN RQMISDYIHF LGNLRWSSLG
310 320 330 340
YTPLYEDNRK EPESMHWVSQ YSNANMVKTD FFEAKSTAYA KSTALEDDL
Length:349
Mass (Da):41,318
Last modified:October 25, 2004 - v1
Checksum:i397DC8C148113650
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006841 Genomic DNA. Translation: BAD49444.1.
RefSeqiWP_011202979.1. NC_006347.1.
YP_099978.1. NC_006347.1.

Genome annotation databases

EnsemblBacteriaiBAD49444; BAD49444; BF2694.
GeneIDi3083574.
KEGGibfr:BF2694.
PATRICi21051019. VBIBacFra17906_2606.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006841 Genomic DNA. Translation: BAD49444.1.
RefSeqiWP_011202979.1. NC_006347.1.
YP_099978.1. NC_006347.1.

3D structure databases

ProteinModelPortaliQ64ST5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD49444; BAD49444; BF2694.
GeneIDi3083574.
KEGGibfr:BF2694.
PATRICi21051019. VBIBacFra17906_2606.

Phylogenomic databases

KOiK00526.
OMAiHWNKLKA.
OrthoDBiEOG6J48J7.

Enzyme and pathway databases

UniPathwayiUPA00326.

Family and domain databases

Gene3Di1.10.620.20. 1 hit.
InterProiIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR000358. RNR_small.
IPR030475. RNR_small_AS.
[Graphical view]
PANTHERiPTHR23409. PTHR23409. 1 hit.
PfamiPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFiPIRSF000355. NrdB. 1 hit.
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00368. RIBORED_SMALL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation."
    Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.
    Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YCH46Imported.

Entry informationi

Entry nameiQ64ST5_BACFR
AccessioniPrimary (citable) accession number: Q64ST5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: June 24, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.