Reviewed, UniProtKB/Swiss-Prot Q64PU2 (KCY_BACFR)

Names and origin

Protein names

Recommended name:
    Cytidylate kinase
      Short name=CK
    EC=2.7.4.14
Alternative name(s):
    Cytidine monophosphate kinase
      Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	BF3747

Organism

Bacteroides fragilis [Complete proteome] [HAMAP]

Taxonomic identifier

817 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 229	229	Cytidylate kinase HAMAP MF_00238		PRO_0000131876
Regions
	Nucleotide binding	10 – 18	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q64PU2-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 0109C089774B9492	FASTA	229	25,649
	10 20 30 40 50 60 MKKITIAIDG FSSCGKSTMA KDLAKEIGYI YIDSGAMYRA VTLYSIENGI FHGDTIDTDE 70 80 90 100 110 120 LKRRIGDIHI SFRIDPETGR PNTYLNGVNV ENKIRTMEVS SKVSPISALG FVREAMVAQQ 130 140 150 160 170 180 QEMGKAKGIV MDGRDIGTTV FPDAELKIFV TASAEIRAQR RYDELKAKGQ ETGFEEILEN 190 200 210 220 VKQRDHIDQT REVSPLKKAD DALLLDNSHL TIAEQKEWLM AEYQKAIKA

References

[1]

"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y. Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YCH46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006841 Genomic DNA. Translation: BAD50489.1.
RefSeq	YP_101023.1.
3D structure databases
SMR	Q64PU2. Positions 1-219.
ModBase	Search...
Genome annotation databases
GeneID	3084828.
GenomeReviews	Gene locus BF3747 in contig AP006841_GR.
KEGG	bfr:BF3747.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG354377.
OMA	DTGLLYR.
PhylomeDB	Q64PU2.
Enzyme and pathway databases
BioCyc	BFRA295405:BF3747-MONOMER.
BRENDA	2.7.4.14. 868.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BACFR

Accession

Primary (citable) accession number: Q64PU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	October 25, 2004
Last modified:	February 9, 2010
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)