Q64NU8 (Q64NU8_BACFR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Ordered Locus Names:

BF4092

Organism

Bacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]

Taxonomic identifier

295405 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	317 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q64NU8 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 6C6CB8BBF4CC7407	FASTA	317	36,120
	10 20 30 40 50 60 MRVIDLIHSN EKTAFSFEIL PPLKGTGIEK LYQTIDTLRE FDPKYINITT HRSEYVYRDL 70 80 90 100 110 120 GNGLFQRNRL RRRPGTVAVA AAIQNKYNIT VVPHILCSGF TQEETEYVLL DLQFLGITDL 130 140 150 160 170 180 LVLRGDKAKH ETVFTPEGDG HHHALDLQQQ INNFNKGIFV DGSEMKVTNT PFSYGVACYP 190 200 210 220 230 240 EKHEEAPNID MDIYWLKKKV EAGAEYAVTQ LFYDNKKYFE FVEKVHQAGI DIPIIPGIKP 250 260 270 280 290 300 FKKISQLNMV PKTFKVDLPE ELTKEALKCQ TDEEARQVGI EWCISQCKEL MAAGVPSIHF 310 YSIGAVDSIK EVAKAIY

References

[1]

"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y. Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YCH46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006841 Genomic DNA. Translation: BAD50834.1.
RefSeq	YP_101368.1. NC_006347.1.
3D structure databases
ProteinModelPortal	Q64NU8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3085173.
GenomeReviews	Gene locus BF4092 in contig AP006841_GR.
KEGG	bfr:BF4092.
PATRIC	21053758. VBIBacFra17906_3943.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG649727.
OMA	ITQMFFD.
PhylomeDB	Q64NU8.
ProtClustDB	CLSK913627.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. IPR004620. MTHF_reductase_bac. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00676. Fadh2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q64NU8_BACFR

Accession

Primary (citable) accession number: Q64NU8

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2004
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)