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Reviewed, UniProtKB/Swiss-Prot Q64MG2 (NTPA_BACFR)

Last modified February 9, 2010. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase
Gene names
Ordered Locus Names: BF4588
OrganismBacteroides fragilis [Complete proteome] [HAMAP]
Taxonomic identifier817 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

NTP + H2O = NDP + phosphate. HAMAP MF_01405

Cofactor

Divalent cations By similarity. HAMAP MF_01405

Subunit structure

Homodimer By similarity. HAMAP MF_01405

Sequence similarities

Belongs to the HAM1 NTPase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionnucleoside-triphosphatase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 194194Nucleoside-triphosphatase HAMAP MF_01405
PRO_0000178123

Sequences

Sequence LengthMass (Da)Tools
Q64MG2-1 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: B7DC34C6EDC4FA40

FASTA19421,620
        10         20         30         40         50         60 
MKRKLVFATN NAHKLEEVSA ILGDKVELLS LNDINCHTDI PETAETLEGN AYLKSSFIYR 

        70         80         90        100        110        120 
NYGLNCFADD TGLEVESLGG APGVYSARYA GGEGHNAEAN MLKLLHELEG KDNRRAQFRT 

       130        140        150        160        170        180 
AISLILDEKE YLFEGIIKGE IIKEKRGDSG FGYDPVFVPE GYDRTFAELG NEIKNQISHR 

       190 
ALAVNKLCEF LRSI 

« Hide

References

[1]"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation."
Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.
Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed: 15466707] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YCH46.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006841 Genomic DNA. Translation: BAD51325.1.
RefSeqYP_101859.1.

3D structure databases

SMRQ64MG2. Positions 4-193.
ModBaseSearch...

Genome annotation databases

GeneID3085664.
GenomeReviewsGene locus BF4588 in contig AP006841_GR.
KEGGbfr:BF4588.
NMPDRfig|295405.3.peg.4576.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697237.
OMAVYTADWA.

Enzyme and pathway databases

BioCycBFRA295405:BF4588-MONOMER.
BRENDA3.6.1.15. 868.

Family and domain databases

HAMAPMF_01405. Nucleoside_triphosp.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. Ham1p_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNTPA_BACFR
AccessionPrimary (citable) accession number: Q64MG2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: October 25, 2004
Last modified: February 9, 2010
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents