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Q64H35 (CCL26_CANFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
C-C motif chemokine 26
Alternative name(s):
Eotaxin-3
Small-inducible cytokine A26
Gene names
Name:CCL26
OrganismCanis familiaris (Dog) (Canis lupus familiaris) [Reference proteome]
Taxonomic identifier9615 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis

Protein attributes

Sequence length94 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Chemotactic for eosinophils and basophils. Binds to CCR3 By similarity.

Subunit structure

Monomer By similarity.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 9471C-C motif chemokine 26
PRO_0000005237

Amino acid modifications

Disulfide bond33 ↔ 57 By similarity
Disulfide bond34 ↔ 73 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q64H35 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: FAC1A201F0981C29

FASTA9411,012
        10         20         30         40         50         60 
MKSFPVAFLV LLIFILSVHR GVTTRGSDVA KFCCFQYSHK ILPWKWIQSY KFTRSSCSQQ 

        70         80         90 
AVIFTTKKGH KVCAQPKEKW VQRYIALLRE QQQS 

« Hide

References

[1]"Identification of coding sequences for canine monocyte chemotactic protein-2 (CCL8), eotaxin 2 (CCL24), eotaxin 3 (CCL26) and C-C chemokine receptor 3 (CCR3)."
Peters I.R., Peeters D., Clercx C., Day M.J.
Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY675236 mRNA. Translation: AAU14061.1.
RefSeqNP_001005253.1. NM_001005253.1.
UniGeneCfa.15813.

3D structure databases

ProteinModelPortalQ64H35.
SMRQ64H35. Positions 24-93.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9615.ENSCAFP00000019729.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSCAFT00000043418; ENSCAFP00000040578; ENSCAFG00000032573.
GeneID448789.
KEGGcfa:448789.

Organism-specific databases

CTD10344.

Phylogenomic databases

eggNOGNOG69247.
GeneTreeENSGT00730000110278.
HOGENOMHOG000036685.
HOVERGENHBG017871.
InParanoidQ64H35.
KOK05514.
OMAWRTESMA.
OrthoDBEOG7CVQ1F.
TreeFamTF334888.

Family and domain databases

InterProIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamPF00048. IL8. 1 hit.
[Graphical view]
SMARTSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMSSF54117. SSF54117. 1 hit.
PROSITEPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20832519.

Entry information

Entry nameCCL26_CANFA
AccessionPrimary (citable) accession number: Q64H35
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: October 25, 2004
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families