Leucocyte common antigen (L-CA) - Mus musculus (Mouse)

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Unreviewed, UniProtKB/TrEMBL Q64730 (Q64730_MOUSE)

Last modified January 19, 2010. Version 61. History...

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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Leucocyte common antigen (L-CA) EMBL AAA39418.1

Gene names

Name:

Ptprc MGI 97810

Organism

Mus musculus (Mouse) EMBL AAA39418.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	1343 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	T cell receptor signaling pathway Inferred from electronic annotation. Source: Compara immunoglobulin biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of B cell proliferation Inferred from electronic annotation. Source: Compara protein amino acid dephosphorylation Inferred from electronic annotation. Source: InterPro regulation of S phase Inferred from electronic annotation. Source: Compara response to gamma radiation Inferred from electronic annotation. Source: Compara
Cellular component	cell surface Inferred from electronic annotation. Source: Compara integral to plasma membrane Inferred from electronic annotation. Source: Compara
Molecular function	protein kinase binding Inferred from electronic annotation. Source: Compara protein tyrosine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

1

EMBL AAA39418.1

Sequences

Sequence

Length

Mass (Da)

Tools

Q64730-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 0DEBDEC97FC4C6A9
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1,343

150,680

        10         20         30         40         50         60 
MGLWLKLLAF GFALLDTEVF VTGQTPTPSD ELSTTENALL LPQSDPLPAR TTESTPPSIS 

        70         80         90        100        110        120 
ERGNGSSETT YHPGVLSTLL PHLSPQPDSQ TPSAGGADTQ TFSSQADNPT LTPAPGGGTD 

       130        140        150        160        170        180 
PPGVPGERTV PGTIPADTAF PVDTPSLARN SSAASPTHTS NVSTTDISSG ASLTTLTPST 

       190        200        210        220        230        240 
LGLASTDPPS TTIATTTKQT CAAMFGNITV NYTYESSNQT FKADLKDVQN AKCGNEDCEN 

       250        260        270        280        290        300 
VLNNLEECSQ IKNISVSNDS CAPATTIDLY VPPGTDKFSL HDCTPKEKAN TSICLEWKTK 

       310        320        330        340        350        360 
NLDFRKCNSD NISYVLHCEP ENNTKCIRRN TFIPERCQLD NLRAQTNYTC VAEILYRGVK 

       370        380        390        400        410        420 
LVKNVINVQT DLGIPETPKP SCGDPAARKT LVSWPEPVSK PESASKPHGY VLCYKNNSEK 

       430        440        450        460        470        480 
CKSLPNNVTS FEVESLKPYK YYEVSLLAYV NGKIQRNGTA EKCNFHTKAD RPDKVNGMKT 

       490        500        510        520        530        540 
SRPTDNSINV TCGPPYETNG PKTFYILVVR SGGSFVTKYN KTNCQFYVDN LYYSTDYEFL 

       550        560        570        580        590        600 
VSFHNGVYEG DSVIRNESTN FNAKALIIFL VFLIIVTSIA LLVVLYKIYD LRKKRSSNLD 

       610        620        630        640        650        660 
EQQELVERDD EKQLMDVEPI HSDILLETYK RKIADEGRLF LAEFQSIPRV FSKFPIKDAR 

       670        680        690        700        710        720 
KPHNQNKNRY VDILPYDYNR VELSEINGDA GSTYINASYI DGFGFKEPRK YIAAQGTRAP 

       730        740        750        760        770        780 
GPRDETVDDF WRMIWEQKAT VIVMVTRCEE GNRNRNKCNK CAEYWPSMEE GTRAFKDIVV 

       790        800        810        820        830        840 
TINDHKRCPD YIIQKLNVAH AHKKKKEKAT GREVTHIQFT SWPDHGVPED PHLLLKLRRR 

       850        860        870        880        890        900 
VNAFSNFFSG PIVVHCSTAV LVAGVGRTGT YIGIDAMLEG LEAEGKVDVY GYVVKLRRQR 

       910        920        930        940        950        960 
CLMVQVEVEA QYAQYILIHQ ALVEYNQFGE TEVNLSELHS CLHNMKKRDP PSDPSPLEAE 

       970        980        990       1000       1010       1020 
YQYQRLRLPS YRSWRTQHIG NQEENKKKNR NSNVVPYDFN RVPLKHELEM SKESEPESDE 

      1030       1040       1050       1060       1070       1080 
SSDDDSDSEE TSKYINASFV MSYWSYWKPE MMIAAQGPLK ETIGDFWQMI FQRKVKVIVM 

      1090       1100       1110       1120       1130       1140 
LTELVNGDQD QEVCEVCAQY WGEGKQTYGD MEVEMKDTNR ASAYTLRTFE LRHSKSKRKR 

      1150       1160       1170       1180       1190       1200 
KEPRTVYQYQ CTTWKGEELP AEPKDLVSMI QDLKQKLPKA SPEGMKYHKH ASILVHCSTA 

      1210       1220       1230       1240       1250       1260 
EMEDGSQQTG LFCALFNLLE SAETEDVVDV FQVVKSLRKA RPGVVCSYSY EQYEQYQFLY 

      1270       1280       1290       1300       1310       1320 
DIIASIYPAQ NGQVKKTNSQ DKIEFHNEVD GGKQDANCVR PDGPLNKAQE DSRGVGTPEP 

      1330       1340 
TNSAEEPEHA ANGSASPAPT QSS

References

[1]	"B-cell variant of mouse T200 (Ly-5): evidence for alternative mRNA splicing." Thomas M.L., Reynolds P.J., Chain A., Ben-Neriah Y., Trowbridge I.S. Proc. Natl. Acad. Sci. U.S.A. 84:5360-5363(1987) [PubMed: 2955416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Sequence conservation in potential regulatory regions of the mouse and human leukocyte common antigen gene." Johnson N.A., Meyer C.M., Pingel J.T., Thomas M.L. J. Biol. Chem. 264:6220-6229(1989) [PubMed: 2522930] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M23158 M23157 Genomic DNA. Translation: AAA39418.1.
IPI	IPI00323053.
UniGene	Mm.391573
3D structure databases
HSSP	HSSP built from PDB template 1YFO based on UniProtKB P18052.
SMR	Q64730. Positions 287-556.
ModBase	Search...
Protein-protein interaction databases
STRING	Q64730.
Genome annotation databases
Ensembl	ENSMUST00000074797; ENSMUSP00000074352; ENSMUSG00000026395; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:97810. Ptprc.
Phylogenomic databases
HOGENOM	HBG717275.
HOVERGEN	Q64730.
InParanoid	Q64730.
Gene expression databases
ArrayExpress	Q64730.
Bgee	Q64730.
Genevestigator	Q64730.
Family and domain databases
InterPro	IPR000387. Dual-sp/Tyr_phosphatase. IPR008957. Fibronectin_typ-III-like_fold. IPR003961. FN_III. IPR016335. Leukocyte_common_Ag. IPR000242. Tyr_Pase_rcpt/non-rcpt. [Graphical view]
Gene3D	G3DSA:2.60.40.30. FN_III-like. 1 hit.
Pfam	PF00102. Y_phosphatase. 2 hits. [Graphical view]
PIRSF	PIRSF002004. Leukocyte_common_antigen. 1 hit.
PRINTS	PR00700. PRTYPHPHTASE.
SMART	SM00060. FN3. 2 hits. SM00194. PTPc. 2 hits. [Graphical view]
PROSITE	PS50853. FN3. 2 hits. PS50056. TYR_PHOSPHATASE_2. 2 hits. PS50055. TYR_PHOSPHATASE_PTP. 2 hits. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q64730_MOUSE

Accession

Primary (citable) accession number: Q64730

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	January 19, 2010
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information