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Protein
Submitted name:

Cytochrome P450 2C12, female-specific

Gene

Cyp2c12

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 2C12, female-specificImported
Submitted name:
Cytochrome P450, family 2, subfamily c, polypeptide 12Imported
Submitted name:
Cytochrome P450, family 2, subfamily c, polypeptide 40Imported
Gene namesi
Name:Cyp2c12Imported
Synonyms:Cyp2c40Imported, LOC100361492Imported
ORF Names:rCG_57447Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi2470 Cyp2c12

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501431025128 – 490Sequence analysisAdd BLAST463

Proteomic databases

PRIDEiQ64648

Expressioni

Gene expression databases

BgeeiENSRNOG00000047945

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140831
HOVERGENiHBG015789
OMAiDMQWRAM
OrthoDBiEOG091G0BT8
TreeFamiTF352043

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q64648-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPFVVLVLS LSFLLLLYLW RPSPGRGKLP PGPTPLPIFG NFLQIDMKDI
60 70 80 90 100
RQSISNFSKT YGPVFTLYFG SQPTVVLHGY EAVKEALIDY GEEFSGRGRM
110 120 130 140 150
PVFEKATKGL GISFSRGNVW RATRHFTVNT LRSLGMGKRT IEIKVQEEAE
160 170 180 190 200
WLVMELKKTK GSPCDPKFII GCAPCNVICS IIFQNRFDYK DKDFLSLIEN
210 220 230 240 250
VNEYIKIVST PAFQVFNAFP ILLDYCPGNH KTHSKHFAAI KSYLLKKIKE
260 270 280 290 300
HEESLDVSNP RDFIDYFLIQ RCQENGNQQM NYTQEHLAIL VTNLFIGGTE
310 320 330 340 350
TSSLTLRFAL LLLMKYPHIT DKVQEEIGQV IGRHRSPCML DRIHMPYTNA
360 370 380 390 400
MIHEVQRYID LAPNGLLHEV TCDTKFRDYF IPKGTAVLTS LTSVLHDSKE
410 420 430 440 450
FPNPEMFDPG HFLDENGNFK KSDYFMPFSA GKRKCVGEGL ASMELFLFLT
460 470 480 490
TILQNFKLKS LSDPKDIDIN SIRSEFSSIP PTFQLCFIPV
Length:490
Mass (Da):55,894
Last modified:November 1, 1996 - v1
Checksum:iAF77EA6A18E27897
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC111446 Genomic DNA No translation available.
AH002221
, M33545, M33546, M33547, M33548, M33549, M33656 Genomic DNA Translation: AAA41784.1
BC089790 mRNA Translation: AAH89790.1
CH473986 Genomic DNA Translation: EDL94176.1
UniGeneiRn.2586

Genome annotation databases

EnsembliENSRNOT00000015801; ENSRNOP00000015802; ENSRNOG00000047945
UCSCiRGD:2320073 rat

Similar proteinsi

Entry informationi

Entry nameiQ64648_RAT
AccessioniPrimary (citable) accession number: Q64648
Secondary accession number(s): D3Z8S1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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