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Protein

Phosphotransferase

Gene

Gck

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
Biological processGlycolysisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
Name:GckImported
ORF Names:rCG_35874Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi2670 Gck

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000061527

Structurei

3D structure databases

SMRiQ64596
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 248Hexokinase_1InterPro annotationAdd BLAST146
Domaini254 – 488Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159
HOGENOMiHOG000162670
HOVERGENiHBG000142
KOiK12407
OMAiERQFFRA
OrthoDBiEOG091G08MD
TreeFamiTF314238

Family and domain databases

InterProiView protein in InterPro
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N
PANTHERiPTHR19443 PTHR19443, 1 hit
PfamiView protein in Pfam
PF00349 Hexokinase_1, 1 hit
PF03727 Hexokinase_2, 1 hit
PROSITEiView protein in PROSITE
PS00378 HEXOKINASE_1, 1 hit
PS51748 HEXOKINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q64596-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMDTTRCGA QLLTLGTNKC TNACSLLCRA GTHNGHMNPR CRTEQAAATQ
60 70 80 90 100
LPTCRVQLLL NYHVEGRADP GRVPAAGGRP EEGDEPDAEG DGPWPEAGDP
110 120 130 140 150
RGEVGDFLSL DLGGTNFRVM LVKVGEGEAG QWSVKTKHQM YSIPEDAMTG
160 170 180 190 200
TAEMLFDYIS ECISDFLDKH QMKHKKLPLG FTFSFPVRHE DLDKGILLNW
210 220 230 240 250
TKGFKASGAE GNNIVGLLRD AIKRRGDFEM DVVAMVNDTV ATMISCYYED
260 270 280 290 300
RQCEVGMIVG TGCNACYMEE MQNVELVEGD EGRMCVNTEW GAFGDSGELD
310 320 330 340 350
EFLLEYDRMV DESSANPGQQ LYEKIIGGKY MGELVRLVLL KLVDENLLFH
360 370 380 390 400
GEASEQLRTR GAFETRFVSQ VESDSGDRKQ IHNILSTLGL RPSVTDCDIV
410 420 430 440 450
RRACESVSTR AAHMCSAGLA GVINRMRESR SEDVMRITVG VDGSVYKLHP
460 470 480 490
SFKERFHASV RRLTPNCEIT FIESEEGSGR GAALVSAVAC KKACMLAQ
Length:498
Mass (Da):54,773
Last modified:November 1, 1996 - v1
Checksum:iD2FAC1383DDFE1C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110110 Genomic DNA No translation available.
X53589 mRNA Translation: CAA37658.1
CH473963 Genomic DNA Translation: EDM00323.1
PIRiS12061
RefSeqiNP_001257778.1, NM_001270849.1
NP_036697.1, NM_012565.2
UniGeneiRn.10447

Genome annotation databases

EnsembliENSRNOT00000080147; ENSRNOP00000068656; ENSRNOG00000061527
GeneIDi24385
KEGGirno:24385

Similar proteinsi

Entry informationi

Entry nameiQ64596_RAT
AccessioniPrimary (citable) accession number: Q64596
Secondary accession number(s): Q63219
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported