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Q64487

- PTPRD_MOUSE

UniProt

Q64487 - PTPRD_MOUSE

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Protein
Receptor-type tyrosine-protein phosphatase delta
Gene
Ptprd
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei1181 – 11822Cleavage By similarity
Binding sitei1521 – 15211Substrate By similarity
Active sitei1553 – 15531Phosphocysteine intermediate By similarity
Binding sitei1597 – 15971Substrate By similarity
Active sitei1844 – 18441Phosphocysteine intermediate By similarity

GO - Molecular functioni

  1. cell adhesion molecule binding Source: BHF-UCL
  2. protein binding Source: UniProtKB
  3. protein tyrosine phosphatase activity Source: UniProtKB-EC
  4. receptor binding Source: BHF-UCL
Complete GO annotation...

GO - Biological processi

  1. heterophilic cell-cell adhesion Source: BHF-UCL
  2. neuron differentiation Source: BHF-UCL
  3. positive regulation of dendrite morphogenesis Source: BHF-UCL
  4. presynaptic membrane assembly Source: BHF-UCL
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase, Receptor

Names & Taxonomyi

Protein namesi
Recommended name:
Receptor-type tyrosine-protein phosphatase delta (EC:3.1.3.48)
Short name:
Protein-tyrosine phosphatase delta
Short name:
R-PTP-delta
Gene namesi
Name:Ptprd
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:97812. Ptprd.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini21 – 12661246Extracellular Reviewed prediction
Add
BLAST
Transmembranei1267 – 128721Helical; Reviewed prediction
Add
BLAST
Topological domaini1288 – 1912625Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 Reviewed prediction
Add
BLAST
Chaini21 – 19121892Receptor-type tyrosine-protein phosphatase delta
PRO_0000025438Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi45 ↔ 98 Reviewed prediction
Disulfide bondi147 ↔ 207 Reviewed prediction
Glycosylationi254 – 2541N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi257 ↔ 302 Reviewed prediction
Glycosylationi299 – 2991N-linked (GlcNAc...) Reviewed prediction
Glycosylationi724 – 7241N-linked (GlcNAc...) Reviewed prediction
Glycosylationi832 – 8321N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization By similarity.

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiQ64487.
PaxDbiQ64487.
PRIDEiQ64487.

PTM databases

PhosphoSiteiQ64487.

Expressioni

Tissue specificityi

Brain, kidney, heart, and some B-cell lines.

Gene expression databases

ArrayExpressiQ64487.
BgeeiQ64487.
CleanExiMM_PTPRD.
GenevestigatoriQ64487.

Interactioni

Subunit structurei

Interacts with PPFIA1, PPFIA2 and PPFIA3 By similarity. Interacts with IL1RAPL1 (via extracellular region); this interaction is required for IL1RAPL1-mediated synapse formation.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
Il1rapl1P598236EBI-771834,EBI-5452114

Protein-protein interaction databases

IntActiQ64487. 3 interactions.
MINTiMINT-129768.

Structurei

3D structure databases

ProteinModelPortaliQ64487.
SMRiQ64487. Positions 21-318, 323-719, 921-1016, 1331-1906.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 11491Ig-like C2-type 1
Add
BLAST
Domaini126 – 22499Ig-like C2-type 2
Add
BLAST
Domaini236 – 31883Ig-like C2-type 3
Add
BLAST
Domaini325 – 41591Fibronectin type-III 1
Add
BLAST
Domaini420 – 51697Fibronectin type-III 2
Add
BLAST
Domaini518 – 60790Fibronectin type-III 3
Add
BLAST
Domaini612 – 70998Fibronectin type-III 4
Add
BLAST
Domaini714 – 822109Fibronectin type-III 5
Add
BLAST
Domaini823 – 91694Fibronectin type-III 6
Add
BLAST
Domaini921 – 101696Fibronectin type-III 7
Add
BLAST
Domaini1020 – 110687Fibronectin type-III 8
Add
BLAST
Domaini1357 – 1612256Tyrosine-protein phosphatase 1
Add
BLAST
Domaini1644 – 1903260Tyrosine-protein phosphatase 2
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni180 – 18910Sufficient for interaction with IL1RAPL1
Regioni227 – 2304Contributes to IL1RAPL1 binding
Regioni1553 – 15597Substrate binding By similarity

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5599.
GeneTreeiENSGT00590000082937.
HOGENOMiHOG000010250.
HOVERGENiHBG053758.
KOiK06777.
OMAiTMDPSQH.
OrthoDBiEOG7M98FB.

Family and domain databases

Gene3Di2.60.40.10. 11 hits.
3.90.190.10. 2 hits.
InterProiIPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00041. fn3. 7 hits.
PF07679. I-set. 3 hits.
PF00102. Y_phosphatase. 2 hits.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00060. FN3. 8 hits.
SM00408. IGc2. 3 hits.
SM00194. PTPc. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 6 hits.
SSF52799. SSF52799. 2 hits.
PROSITEiPS50853. FN3. 8 hits.
PS50835. IG_LIKE. 3 hits.
PS00383. TYR_PHOSPHATASE_1. 2 hits.
PS50056. TYR_PHOSPHATASE_2. 2 hits.
PS50055. TYR_PHOSPHATASE_PTP. 2 hits.
[Graphical view]

Sequences (12)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 12 isoformsi produced by alternative splicing. Align

Note: Additional isoforms seem to exist.

Isoform D (identifier: Q64487-4) [UniParc]FASTAAdd to Basket

Also known as: delta

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MVPVARPLSL LLTFFLCACA ETPPRFTRTP VDQTGVSGGV ASFICQATGD     50
PRPKIVWNKK GKKVSNQRFE VIEFDDGSGS VLRIQPLRTP RDEAIYECVA 100
SNNVGEISVS TRLTVLREDQ IPRGFPTIDM GPQLKVVERT RTATMLCAAS 150
GNPDPEITWF KDFLPVDTSN NNGRIKQLRS ESIGGTPIRG ALQIEQSEES 200
DQGKYECVAT NSAGTRYSAP ANLYVRELRE VRRVPPRFSI PPTNHEIMPG 250
GSVNITCVAV GSPMPYVKWM LGAEDLTPED DMPIGRNVLE LNDVRQSANY 300
TCVAMSTLGV IEAIAQITVK ALPKPPGTPV VTESTATSIT LTWDSGNPEP 350
VSYYIIQHKP KNSEEPYKEI DGIATTRYSV AGLSPYSDYE FRVVAVNNIG 400
RGPASEPVLT QTSEQAPSSA PRDVQARMLS STTILVQWKE PEEPNGQIQG 450
YRVYYTMDPT QHVNNWMKHN VADSQITTIG NLVPQKTYSV KVLAFTSIGD 500
GPLSSDIQVI TQTGVPGQPL NFKAEPESET SILLSWTPPR SDTIASYELV 550
YRDGDQGEEQ RITIEPGTSY RLQGLKPNSL YYFRLSARSP QGLGASTAEI 600
SARTMQSKPS APPQDISCTS PSSTSILVSW QPPPVEKQNG IITEYSLKYA 650
AVDGEDFKPH EILGIPSDTT KYLLEQLEKW TEYRITVTAH TDVGPGPESL 700
SVLIRTDEDV PSGPPRKVEV EAVNATAVKV SWRSPVPNKQ HGQIRGYQVH 750
YVKMENGEPK GQPMLKDVML ADAQWEFDDT TEHDMIISGL QPETSYSLTV 800
TAYTTKGDGA RSKPKLVSTT GAVPGKPRLV INHTQMNTAL IQWHPPVDTF 850
GPLQGYRLKF GRKDMEPLTT LEFSEKEDHF TATDIHKGAS YVFRLSARNK 900
VGFGEEMVKE ISVPEEIPTG FPQNLHSEGT TSTSVQLSWQ PPVLAERNGV 950
ITKYTLLYRD INVPLLPMEH LIVPADTSMT LTGLKSDTTY DVKVRAHTSK 1000
GPGPYSPSVQ FRTLPVDQVF AKNFHVKAVM KTSVLLSWEI PENYNSAMPF 1050
KILYDDGKMV EEVDGRATQK LIVNLKPEKS YSFVLTNRGN SAGGLQHRVT 1100
AKTAPDVLRT KPAFIGKTNL DGMITVQLPD VPANENIKGY YIIIVPLKKS 1150
RGKFIKPWES PDEMELDELL KEISRKRRSI RYGREVELKP YIAAHFDVLP 1200
TEFTLGDDKH YGGFTNKQLQ SGQEYVFFVL AVMDHAESKM YATSPYSDPV 1250
VSMDLDPQPI TDEEEGLIWV VGPVLAVVFI ICIVIAILLY KRKRAESESR 1300
KSSLPNSKEV PSHHPTDPVE LRRLNFQTPG MASHPPIPIL ELADHIERLK 1350
ANDNLKFSQE YESIDPGQQF TWEHSNLEVN KPKNRYANVI AYDHSRVLLS 1400
AIEGIPGSDY VNANYIDGYR KQNAYIATQG SLPETFGDFW RMIWEQRSAT 1450
VVMMTKLEER SRVKCDQYWP SRGTETHGLV QVTLLDTVEL ATYCVRTFAL 1500
YKNGSSEKRE VRQFQFTAWP DHGVPEHPTP FLAFLRRVKT CNPPDAGPMV 1550
VHCSAGVGRT GCFIVIDAML ERIKHEKTVD IYGHVTLMRA QRNYMVQTED 1600
QYIFIHDALL EAVTCGNTEV PARNLYAYIQ KLTQIETGEN VTGMELEFKR 1650
LASSKAHTSR FISANLPCNK FKNRLVNIMP YESTRVCLQP IRGVEGSDYI 1700
NASFLDGYRQ QKAYIATQGP LAETTEDFWR MLWEHNSTIV VMLTKLREMG 1750
REKCHQYWPA ERSARYQYFV VDPMAEYNMP QYILREFKVT DARDGQSRTV 1800
RQFQFTDWPE QGVPKSGEGF IDFIGQVHKT KEQFGQDGPI SVHCSAGVGR 1850
TGVFITLSIV LERMRYEGVV DIFQTVKMLR TQRPAMVQTE DQYQFCYRAA 1900
LEYLGSFDHY AT 1912
Length:1,912
Mass (Da):214,410
Last modified:May 16, 2012 - v3
Checksum:iDEF494AA5A2CE814
GO
Isoform C (identifier: Q64487-1) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     184-189: Missing.
     227-230: Missing.
     775-783: Missing.

Show »
Length:1,893
Mass (Da):212,139
Checksum:i75E8EA527026E69B
GO
Isoform A (identifier: Q64487-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MCLTSCFILASHMLSCDLVFVP
     2-230: Missing.
     608-1018: Missing.
     1019-1019: V → M

Show »
Length:1,293
Mass (Da):146,050
Checksum:iBB720DA7CCF34DD6
GO
Isoform B (identifier: Q64487-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MCLTSCFILASHMLSCDLVFVP
     2-230: Missing.
     775-783: Missing.

Show »
Length:1,695
Mass (Da):190,371
Checksum:i386F0DB5ACDD4C89
GO
Isoform E (identifier: Q64487-5) [UniParc]FASTAAdd to Basket

Also known as: delta-DelB

The sequence of this isoform differs from the canonical sequence as follows:
     227-230: Missing.

Show »
Length:1,908
Mass (Da):213,882
Checksum:iD95358289FF1576B
GO
Isoform F (identifier: Q64487-6) [UniParc]FASTAAdd to Basket

Also known as: deltaA6

The sequence of this isoform differs from the canonical sequence as follows:
     181-183: Missing.

Show »
Length:1,909
Mass (Da):214,080
Checksum:iA4103C1071DB834A
GO
Isoform G (identifier: Q64487-7) [UniParc]FASTAAdd to Basket

Also known as: deltaA6-DelB

The sequence of this isoform differs from the canonical sequence as follows:
     181-183: Missing.
     227-230: Missing.

Show »
Length:1,905
Mass (Da):213,553
Checksum:iB2A43376C7BFBA17
GO
Isoform H (identifier: Q64487-8) [UniParc]FASTAAdd to Basket

Also known as: deltaA3

The sequence of this isoform differs from the canonical sequence as follows:
     184-189: Missing.

Show »
Length:1,906
Mass (Da):213,828
Checksum:i5CD10161556D78FC
GO
Isoform I (identifier: Q64487-9) [UniParc]FASTAAdd to Basket

Also known as: deltaA3-DelB

The sequence of this isoform differs from the canonical sequence as follows:
     184-189: Missing.
     227-230: Missing.

Show »
Length:1,902
Mass (Da):213,300
Checksum:iE612C8C07FCF9632
GO
Isoform J (identifier: Q64487-10) [UniParc]FASTAAdd to Basket

Also known as: delta-DelA

The sequence of this isoform differs from the canonical sequence as follows:
     181-189: Missing.

Show »
Length:1,903
Mass (Da):213,499
Checksum:i978F592FB8113D1A
GO
Isoform K (identifier: Q64487-11) [UniParc]FASTAAdd to Basket

Also known as: delta-DelAB

The sequence of this isoform differs from the canonical sequence as follows:
     181-189: Missing.
     227-230: Missing.

Show »
Length:1,899
Mass (Da):212,971
Checksum:iEB6E8D26E1900A38
GO
Isoform L (identifier: Q64487-12) [UniParc]FASTAAdd to Basket

Also known as: delta A

The sequence of this isoform differs from the canonical sequence as follows:
     608-1018: Missing.
     1019-1019: V → M

Show »
Length:1,501
Mass (Da):168,928
Checksum:i141D4F9E90F088AD
GO

Sequence cautioni

The sequence BAA03004.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11M → MCLTSCFILASHMLSCDLVF VP in isoform A and isoform B.
VSP_043545
Alternative sequencei2 – 230229Missing in isoform A and isoform B.
VSP_043546Add
BLAST
Alternative sequencei181 – 1899Missing in isoform J and isoform K.
VSP_043547
Alternative sequencei181 – 1833Missing in isoform F and isoform G.
VSP_043548
Alternative sequencei184 – 1896Missing in isoform C, isoform H and isoform I.
VSP_043549
Alternative sequencei227 – 2304Missing in isoform C, isoform E, isoform G, isoform I and isoform K.
VSP_043550
Alternative sequencei608 – 1018411Missing in isoform A and isoform L.
VSP_043551Add
BLAST
Alternative sequencei775 – 7839Missing in isoform B and isoform C.
VSP_043552
Alternative sequencei1019 – 10191V → M in isoform A and isoform L.
VSP_043553

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti5 – 51A → R in BAA03004. 1 Publication
Sequence conflicti349 – 3491E → G in BAA03003. 1 Publication
Sequence conflicti416 – 4161A → T in BAA03003. 1 Publication
Sequence conflicti551 – 5511Y → D in BAA03003. 1 Publication
Sequence conflicti588 – 5881R → T in BAA03003. 1 Publication
Sequence conflicti657 – 6571F → Y in BAA03005. 1 Publication
Sequence conflicti663 – 6664LGIP → IGNS in BAA03005. 1 Publication
Sequence conflicti696 – 6961G → W in BAA03005. 1 Publication
Sequence conflicti761 – 7633GQP → SA in BAA03005. 1 Publication
Sequence conflicti822 – 8221A → S in BAA03005. 1 Publication
Sequence conflicti852 – 8521Missing in BAA03005. 1 Publication
Sequence conflicti1001 – 10011G → R in BAA03005. 1 Publication
Sequence conflicti1004 – 10041P → A in BAA03005. 1 Publication
Sequence conflicti1046 – 105510SAMPFKILYD → PAILSKFFMMM in BAA03003. 1 Publication
Sequence conflicti1084 – 10841V → A in BAA03003. 1 Publication
Sequence conflicti1298 – 12981E → D in BAA03003. 1 Publication
Sequence conflicti1447 – 14482RS → E in BAA03003. 1 Publication
Sequence conflicti1491 – 150212ATYCV…FALYK → HILCPDICTLN in BAA03003. 1 Publication
Add
BLAST
Sequence conflicti1510 – 15101E → K in BAA03003. 1 Publication
Sequence conflicti1531 – 154212FLAFL…VKTCN → VPSFLTESQNLH in BAA03003. 1 Publication
Add
BLAST
Sequence conflicti1684 – 16841T → G in BAA03003. 1 Publication
Sequence conflicti1786 – 179510EFKVTDARDG → NSRSRMPGI in BAA03003. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D13903 mRNA. Translation: BAA03003.1.
D13905 mRNA. Translation: BAA03005.1.
D13904 mRNA. Translation: BAA03004.1. Different initiation.
AF326559 mRNA. Translation: AAL37405.1.
AF326560 mRNA. Translation: AAL37406.1.
AL844848 Genomic DNA. No translation available.
AL845517 Genomic DNA. No translation available.
AL929181 Genomic DNA. No translation available.
Z23051 mRNA. Translation: CAA80586.1.
PIRiC54689.
D54689.
RefSeqiNP_035341.2. NM_011211.3.
UniGeneiMm.184021.
Mm.403663.
Mm.477158.
Mm.489057.

Genome annotation databases

EnsembliENSMUST00000107289; ENSMUSP00000102910; ENSMUSG00000028399. [Q64487-4]
GeneIDi19266.
KEGGimmu:19266.
UCSCiuc008tjl.1. mouse.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D13903 mRNA. Translation: BAA03003.1 .
D13905 mRNA. Translation: BAA03005.1 .
D13904 mRNA. Translation: BAA03004.1 . Different initiation.
AF326559 mRNA. Translation: AAL37405.1 .
AF326560 mRNA. Translation: AAL37406.1 .
AL844848 Genomic DNA. No translation available.
AL845517 Genomic DNA. No translation available.
AL929181 Genomic DNA. No translation available.
Z23051 mRNA. Translation: CAA80586.1 .
PIRi C54689.
D54689.
RefSeqi NP_035341.2. NM_011211.3.
UniGenei Mm.184021.
Mm.403663.
Mm.477158.
Mm.489057.

3D structure databases

ProteinModelPortali Q64487.
SMRi Q64487. Positions 21-318, 323-719, 921-1016, 1331-1906.
ModBasei Search...

Protein-protein interaction databases

IntActi Q64487. 3 interactions.
MINTi MINT-129768.

PTM databases

PhosphoSitei Q64487.

Proteomic databases

MaxQBi Q64487.
PaxDbi Q64487.
PRIDEi Q64487.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000107289 ; ENSMUSP00000102910 ; ENSMUSG00000028399 . [Q64487-4 ]
GeneIDi 19266.
KEGGi mmu:19266.
UCSCi uc008tjl.1. mouse.

Organism-specific databases

CTDi 5789.
MGIi MGI:97812. Ptprd.

Phylogenomic databases

eggNOGi COG5599.
GeneTreei ENSGT00590000082937.
HOGENOMi HOG000010250.
HOVERGENi HBG053758.
KOi K06777.
OMAi TMDPSQH.
OrthoDBi EOG7M98FB.

Miscellaneous databases

ChiTaRSi PTPRD. mouse.
NextBioi 296140.
PROi Q64487.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q64487.
Bgeei Q64487.
CleanExi MM_PTPRD.
Genevestigatori Q64487.

Family and domain databases

Gene3Di 2.60.40.10. 11 hits.
3.90.190.10. 2 hits.
InterProi IPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view ]
Pfami PF00041. fn3. 7 hits.
PF07679. I-set. 3 hits.
PF00102. Y_phosphatase. 2 hits.
[Graphical view ]
PRINTSi PR00700. PRTYPHPHTASE.
SMARTi SM00060. FN3. 8 hits.
SM00408. IGc2. 3 hits.
SM00194. PTPc. 2 hits.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 6 hits.
SSF52799. SSF52799. 2 hits.
PROSITEi PS50853. FN3. 8 hits.
PS50835. IG_LIKE. 3 hits.
PS00383. TYR_PHOSPHATASE_1. 2 hits.
PS50056. TYR_PHOSPHATASE_2. 2 hits.
PS50055. TYR_PHOSPHATASE_PTP. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "MPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineage."
    Mizuno K., Hasegawa K., Katagiri T., Ogimoto M., Ichikawa T., Yakura H.
    Mol. Cell. Biol. 13:5513-5523(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A), NUCLEOTIDE SEQUENCE [MRNA] OF 1-224 (ISOFORMS C/H/I), NUCLEOTIDE SEQUENCE [MRNA] OF 606-1018 (ISOFORMS B/C), ALTERNATIVE SPLICING (ISOFORMS A; B AND C).
    Strain: BALB/c.
    Tissue: Brain.
  2. "Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene."
    Fehr C., Shirley R.L., Belknap J.K., Crabbe J.C., Buck K.J.
    J. Neurosci. 22:3730-3738(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM L).
    Strain: C57BL/6J and DBA/2J.
    Tissue: Brain.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain."
    Hendriks W., Schepens J., Brugman C., Zeeuwen P., Wieringa B.
    Biochem. J. 305:499-504(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1446-1551.
    Strain: BALB/c.
    Tissue: Brain.
  5. "IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase delta."
    Yoshida T., Yasumura M., Uemura T., Lee S.J., Ra M., Taguchi R., Iwakura Y., Mishina M.
    J. Neurosci. 31:13485-13499(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH IL1RAPL1, ALTERNATIVE SPLICING (ISOFORMS D/E/F/G/H/I/J/K), IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiPTPRD_MOUSE
AccessioniPrimary (citable) accession number: Q64487
Secondary accession number(s): G3X9S7
, Q64486, Q64488, Q64495, Q8VBV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: May 16, 2012
Last modified: June 11, 2014
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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