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Protein
Submitted name:

Testosterone 16a-hydroxylase type b

Gene

16aoh-b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Testosterone 16a-hydroxylase type bImported
Gene namesi
Name:16aoh-bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 491467Sequence analysisPRO_5004266964Add
BLAST

Proteomic databases

PaxDbiQ64460.
PRIDEiQ64460.

PTM databases

iPTMnetiQ64460.
PhosphoSiteiQ64460.

Interactioni

Protein-protein interaction databases

IntActiQ64460. 1 interaction.
MINTiMINT-4109987.
STRINGi10090.ENSMUSP00000005669.

Structurei

3D structure databases

ProteinModelPortaliQ64460.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
HOVERGENiHBG015789.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008068. Cyt_P450_E_grp-I_CYP2B-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01685. EP450ICYP2B.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q64460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPSVLLLLA VLLSLFLLLV RGHAKIHGHL PPGPRPLPLL GNLLQMDRGG
60 70 80 90 100
LLKCFIHLQE KHGDVFTVHL GPRPVVVLCG TQTIREALVN NAEAFSGRGT
110 120 130 140 150
IAAAQLVMQD YGIFFSSGER WKTLRRFSLA TMKEFGMGKR SVEERIKEEA
160 170 180 190 200
QCLVEELKKY QGAPLDPTFF FQCVTANIIC SIVFGERFDY TDEQFLRLLN
210 220 230 240 250
LMYQIYSLLR SFSCQMFELF SGLLKYFPGV HRQIAKNQQE ILNFITHRVE
260 270 280 290 300
KHRASLDPSE PRDFIDTYLL RMEKEKSNHN TEFHHQNLMM SVLSLFFAGT
310 320 330 340 350
ETTSTTLCCG FLLMLMYPHV AGKVQKEIDQ VIGSHRLPTL DDRTKMPYTD
360 370 380 390 400
AVIHEIQRFS DIVPTGAPHR VTKDTMFRGY LLPKNTEVYP ILSSALHDPQ
410 420 430 440 450
YFEQPDSFNP DHFLDANGAL KKSEAFLPFS TGKRICLGES IARNELFLFF
460 470 480 490
TSILQNFSVA SPVASKDIDL TPKESGIGKI PPTYQICFLA R
Length:491
Mass (Da):55,760
Last modified:November 1, 1996 - v1
Checksum:i65C7ED2926E33C34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60358
, M60352, M60353, M60354, M60355, M60356, M60357 Genomic DNA. Translation: AAA03647.1.
PIRiI49625.
UniGeneiMm.482696.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60358
, M60352, M60353, M60354, M60355, M60356, M60357 Genomic DNA. Translation: AAA03647.1.
PIRiI49625.
UniGeneiMm.482696.

3D structure databases

ProteinModelPortaliQ64460.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ64460. 1 interaction.
MINTiMINT-4109987.
STRINGi10090.ENSMUSP00000005669.

PTM databases

iPTMnetiQ64460.
PhosphoSiteiQ64460.

Proteomic databases

PaxDbiQ64460.
PRIDEiQ64460.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
HOVERGENiHBG015789.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008068. Cyt_P450_E_grp-I_CYP2B-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01685. EP450ICYP2B.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structures and characterization of sex-specific mouse cytochrome P-450 genes as members within a large family. Duplication boundary and evolution."
    Lakso M., Masaki R., Noshiro M., Negishi M.
    Eur. J. Biochem. 195:477-486(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ64460_MOUSE
AccessioniPrimary (citable) accession number: Q64460
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 16, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.