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Protein
Submitted name:

Amyloid beta (A4)-like protein 2, isoform CRA_b

Gene

Aplp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Amyloid beta (A4)-like protein 2, isoform CRA_bImported
Submitted name:
CDE1-binding protein CDEBPImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Aplp2Imported
Synonyms:CdebpImported
ORF Names:mCG_14974Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88047. Aplp2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei626 – 648HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_500878191332 – 695Sequence analysisAdd BLAST664

Expressioni

Gene expression databases

BgeeiENSMUSG00000031996.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 204A4_EXTRAInterPro annotationAdd BLAST163

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG000051.

Family and domain databases

Gene3Di3.30.1490.140. 1 hit.
3.90.570.10. 1 hit.
InterProiIPR008155. Amyloid_glyco.
IPR011178. Amyloid_glyco_Cu-bd.
IPR024329. Amyloid_glyco_E2_domain.
IPR008154. Amyloid_glyco_extra.
IPR019744. Amyloid_glyco_extracell_CS.
IPR015849. Amyloid_glyco_heparin-bd.
IPR019745. Amyloid_glyco_intracell_CS.
IPR019543. APP_amyloid_C.
[Graphical view]
PfamiPF10515. APP_amyloid. 1 hit.
PF12924. APP_Cu_bd. 1 hit.
PF12925. APP_E2. 1 hit.
PF02177. APP_N. 1 hit.
[Graphical view]
PRINTSiPR00203. AMYLOIDA4.
SMARTiSM00006. A4_EXTRA. 1 hit.
[Graphical view]
SUPFAMiSSF109843. SSF109843. 1 hit.
SSF56491. SSF56491. 1 hit.
SSF89811. SSF89811. 1 hit.
PROSITEiPS00319. A4_EXTRA. 1 hit.
PS00320. A4_INTRA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q64348-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATGTAAAA ATGKLLVLLL LGLTAPAAAL AGYIEALAAN AGTGFAVAEP
60 70 80 90 100
QIAMFCGKLN MHVNIQTGKW EPDPTGTKSC LGTKEEVLQY CQEIYPELQI
110 120 130 140 150
TNVMEANQPV NIDSWCRRDK RQCKSHIVIP FKCLVGEFVS DVLLVPDNCQ
160 170 180 190 200
FFHQERMEVC EKHQRWHTLV KEACLTEGLT LYSYGMLLPC GVDQFHGTEY
210 220 230 240 250
VCCPQTKTVD SDSTMSKEEE EEEEDEEDEE EDYDLDKSEF PTEADLEDFT
260 270 280 290 300
EAAADEEEED EEEGEEVVED RDYYYDPFKG DDYNEENPTE PSSEGTISDK
310 320 330 340 350
EIVHDVKVPP TPLPTNDVDV YFETSADDNE HARFQKAKEQ LEIRHRNRMD
360 370 380 390 400
RVKKEWEEAE LQAKNLPKTE RQTLIQHFQA MVKALEKEAA SEKQQLVETH
410 420 430 440 450
LARVEAMLND RRRIALENYL AALQSDPPRP HRILQALRRY VRAENKDRLH
460 470 480 490 500
TIRHYQHVLA VDPEKAAQMK SQVMTHLHVI EERRNQSLSL LYKVPYVAQE
510 520 530 540 550
IQEEIDELLQ EQRADMDQFT SSISENPVDV RVSSEESEEI PPFHPLHPFP
560 570 580 590 600
SLSENEGSGM AEQDGGLIGA EEKVINSKNK MDENMVIDET LDVKEMIFNA
610 620 630 640 650
ERVGGLEEEP ESVGPLREDF SLSSNALIGL LVIAVAIATV IVISLVMLRK
660 670 680 690
RQYGTISHGI VEVDPMLTPE ERHLNKMQNH GYENPTYKYL EQMQI
Length:695
Mass (Da):78,998
Last modified:November 1, 1996 - v1
Checksum:iADB62430849EF6AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH004870
, U37468, U37469, U37470, U37471, U37472, U37473, U37476, U37477, U37478, U37479, U37480, U37482, U37483, U37484 Genomic DNA. Translation: AAB38115.1.
Z27070 mRNA. Translation: CAA81583.1.
CH466522 Genomic DNA. Translation: EDL25340.1.
RefSeqiNP_033821.1. NM_009691.2.
UniGeneiMm.19133.

Genome annotation databases

GeneIDi11804.
UCSCiuc009orn.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH004870
, U37468, U37469, U37470, U37471, U37472, U37473, U37476, U37477, U37478, U37479, U37480, U37482, U37483, U37484 Genomic DNA. Translation: AAB38115.1.
Z27070 mRNA. Translation: CAA81583.1.
CH466522 Genomic DNA. Translation: EDL25340.1.
RefSeqiNP_033821.1. NM_009691.2.
UniGeneiMm.19133.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11804.
UCSCiuc009orn.1. mouse.

Organism-specific databases

CTDi334.
MGIiMGI:88047. Aplp2.

Phylogenomic databases

HOVERGENiHBG000051.

Miscellaneous databases

ChiTaRSiAplp2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031996.

Family and domain databases

Gene3Di3.30.1490.140. 1 hit.
3.90.570.10. 1 hit.
InterProiIPR008155. Amyloid_glyco.
IPR011178. Amyloid_glyco_Cu-bd.
IPR024329. Amyloid_glyco_E2_domain.
IPR008154. Amyloid_glyco_extra.
IPR019744. Amyloid_glyco_extracell_CS.
IPR015849. Amyloid_glyco_heparin-bd.
IPR019745. Amyloid_glyco_intracell_CS.
IPR019543. APP_amyloid_C.
[Graphical view]
PfamiPF10515. APP_amyloid. 1 hit.
PF12924. APP_Cu_bd. 1 hit.
PF12925. APP_E2. 1 hit.
PF02177. APP_N. 1 hit.
[Graphical view]
PRINTSiPR00203. AMYLOIDA4.
SMARTiSM00006. A4_EXTRA. 1 hit.
[Graphical view]
SUPFAMiSSF109843. SSF109843. 1 hit.
SSF56491. SSF56491. 1 hit.
SSF89811. SSF89811. 1 hit.
PROSITEiPS00319. A4_EXTRA. 1 hit.
PS00320. A4_INTRA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ64348_MOUSE
AccessioniPrimary (citable) accession number: Q64348
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.