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Protein

40S ribosomal protein S4, X isoform

Gene

rps4x

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • brain development Source: ZFIN
  • chordate embryonic development Source: ZFIN
  • translation Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-DRE-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DRE-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DRE-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-DRE-72649 Translation initiation complex formation
R-DRE-72689 Formation of a pool of free 40S subunits
R-DRE-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-DRE-72702 Ribosomal scanning and start codon recognition
R-DRE-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DRE-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DRE-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4, X isoform
Gene namesi
Name:rps4x
Synonyms:rps4
ORF Names:zgc:92076
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-040927-19 rps4x

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001308242 – 26340S ribosomal protein S4, X isoformAdd BLAST262

Proteomic databases

PaxDbiQ642H9
PRIDEiQ642H9

Expressioni

Gene expression databases

BgeeiENSDARG00000014690

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000108089

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 105S4 RNA-bindingAdd BLAST64

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0378 Eukaryota
COG1471 LUCA
GeneTreeiENSGT00390000005569
HOGENOMiHOG000231325
HOVERGENiHBG000935
InParanoidiQ642H9
KOiK02987
OMAiRKDYKFP
OrthoDBiEOG091G0MYF
PhylomeDBiQ642H9
TreeFamiTF300612

Family and domain databases

CDDicd00165 S4, 1 hit
Gene3Di2.30.30.30, 1 hit
2.40.50.740, 1 hit
HAMAPiMF_00485 Ribosomal_S4e, 1 hit
InterProiView protein in InterPro
IPR032277 40S_S4_C
IPR005824 KOW
IPR014722 Rib_L2_dom2
IPR000876 Ribosomal_S4e
IPR013845 Ribosomal_S4e_central_region
IPR038237 Ribosomal_S4e_central_sf
IPR013843 Ribosomal_S4e_N
IPR018199 Ribosomal_S4e_N_CS
IPR002942 S4_RNA-bd
PANTHERiPTHR11581 PTHR11581, 1 hit
PfamiView protein in Pfam
PF16121 40S_S4_C, 1 hit
PF00467 KOW, 1 hit
PF00900 Ribosomal_S4e, 1 hit
PF08071 RS4NT, 1 hit
PF01479 S4, 1 hit
PIRSFiPIRSF002116 Ribosomal_S4, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667 Ribosomal_S4e_central, 1 hit
SMARTiView protein in SMART
SM00363 S4, 1 hit
PROSITEiView protein in PROSITE
PS00528 RIBOSOMAL_S4E, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q642H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN
60 70 80 90 100
RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPTGFMDVV SIEKTGENFR
110 120 130 140 150
LIYDVKGRFT VHRITNEEAK YKLCKVRKIL IGTKGIPHLV THDARTIRYP
160 170 180 190 200
DPLIKVNDTI RIDLDTGKIT DFIKFETGNM CMVTGGANLG RIGVITNREK
210 220 230 240 250
HPGSFDVVHV KDSIGNSFAT RLSNIFVIGK GNKPWVSLPR GKGVRLTIAE
260
ERDKRLAAKQ SSS
Length:263
Mass (Da):29,688
Last modified:January 23, 2007 - v3
Checksum:i6896BC99E0FC0AB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC081584 mRNA Translation: AAH81584.1
RefSeqiNP_001005589.1, NM_001005589.1
UniGeneiDr.26403

Genome annotation databases

EnsembliENSDART00000128917; ENSDARP00000108089; ENSDARG00000014690
GeneIDi449547
KEGGidre:449547

Similar proteinsi

Entry informationi

Entry nameiRS4X_DANRE
AccessioniPrimary (citable) accession number: Q642H9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 99 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
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