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Protein

Olfactory marker protein

Gene

Omp

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May act as a modulator of the olfactory signal-transduction cascade.

GO - Molecular functioni

  • signal transducer activity Source: MGI

GO - Biological processi

  • chemical synaptic transmission Source: GO_Central
  • neurogenesis Source: MGI
  • sensory perception of smell Source: MGI

Keywordsi

Biological processOlfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory marker protein
Gene namesi
Name:Omp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:97436 Omp

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000580452 – 163Olfactory marker proteinAdd BLAST162

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ64288
PaxDbiQ64288
PRIDEiQ64288

PTM databases

iPTMnetiQ64288
PhosphoSitePlusiQ64288

Expressioni

Tissue specificityi

Uniquely associated with mature olfactory receptor neurons.

Gene expression databases

BgeeiENSMUSG00000074006
CleanExiMM_OMP
ExpressionAtlasiQ64288 baseline and differential
GenevisibleiQ64288 MM

Interactioni

Subunit structurei

Interacts with BEX1 and BEX2.2 Publications

Protein-protein interaction databases

IntActiQ64288, 1 interactor
MINTiQ64288
STRINGi10090.ENSMUSP00000095882

Structurei

Secondary structure

1163
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi10 – 14Combined sources5
Helixi19 – 34Combined sources16
Beta strandi50 – 56Combined sources7
Beta strandi61 – 83Combined sources23
Turni89 – 91Combined sources3
Helixi96 – 98Combined sources3
Beta strandi104 – 108Combined sources5
Beta strandi110 – 112Combined sources3
Beta strandi115 – 117Combined sources3
Helixi119 – 135Combined sources17
Beta strandi137 – 145Combined sources9
Helixi151 – 153Combined sources3
Beta strandi154 – 162Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1F35X-ray2.30A/B2-163[»]
1JOBX-ray2.40A2-163[»]
1JODX-ray3.20A/B2-163[»]
ProteinModelPortaliQ64288
SMRiQ64288
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ64288

Family & Domainsi

Sequence similaritiesi

Belongs to the olfactory marker protein family.Curated

Phylogenomic databases

eggNOGiENOG410IZPX Eukaryota
ENOG410YJIN LUCA
GeneTreeiENSGT00390000009497
HOGENOMiHOG000236315
HOVERGENiHBG007595
InParanoidiQ64288
OMAiHWTPDLT
OrthoDBiEOG091G0OS2
PhylomeDBiQ64288
TreeFamiTF330820

Family and domain databases

Gene3Di2.60.120.390, 1 hit
InterProiView protein in InterPro
IPR009103 Olfactory_marker
IPR036727 Olfactory_marker_sf
PANTHERiPTHR15357 PTHR15357, 1 hit
PfamiView protein in Pfam
PF06554 Olfactory_mark, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD022055 Olfactory_marker, 1 hit
SUPFAMiSSF63697 SSF63697, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q64288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEDGPQKQQ LEMPLVLDQD LTQQMRLRVE SLKQRGEKKQ DGEKLIRPAE
60 70 80 90 100
SVYRLDFIQQ QKLQFDHWNV VLDKPGKVTI TGTSQNWTPD LTNLMTRQLL
110 120 130 140 150
DPAAIFWRKE DSDAMDWNEA DALEFGERLS DLAKIRKVMY FLITFGEGVE
160
PANLKASVVF NQL
Length:163
Mass (Da):18,867
Last modified:January 23, 2007 - v3
Checksum:iD50EA5937D7EAE16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02557 Unassigned DNA Translation: AAA18415.1
U01213 Genomic DNA Translation: AAA20486.1
BC046600 mRNA Translation: AAH46600.1
CCDSiCCDS21466.1
PIRiB54261
RefSeqiNP_035140.1, NM_011010.2
UniGeneiMm.440368

Genome annotation databases

EnsembliENSMUST00000098281; ENSMUSP00000095882; ENSMUSG00000074006
GeneIDi18378
KEGGimmu:18378
UCSCiuc009ike.1 mouse

Similar proteinsi

Entry informationi

Entry nameiOMP_MOUSE
AccessioniPrimary (citable) accession number: Q64288
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 128 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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