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Protein

Olfactory marker protein

Gene

Omp

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

May act as a modulator of the olfactory signal-transduction cascade.

GO - Molecular functioni

  • signal transducer activity Source: MGI

GO - Biological processi

  • chemical synaptic transmission Source: GO_Central
  • neurogenesis Source: MGI
  • sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory marker protein
Gene namesi
Name:Omp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:97436. Omp.

Subcellular locationi

GO - Cellular componenti

  • axon Source: MGI
  • cytoplasm Source: MGI
  • cytosol Source: MGI
  • neuronal cell body Source: MGI
  • nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000580452 – 163Olfactory marker proteinAdd BLAST162

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ64288.
PaxDbiQ64288.
PRIDEiQ64288.

PTM databases

iPTMnetiQ64288.
PhosphoSitePlusiQ64288.

Expressioni

Tissue specificityi

Uniquely associated with mature olfactory receptor neurons.

Gene expression databases

BgeeiENSMUSG00000074006.
CleanExiMM_OMP.
ExpressionAtlasiQ64288. baseline and differential.
GenevisibleiQ64288. MM.

Interactioni

Subunit structurei

Interacts with BEX1 and BEX2.2 Publications

Protein-protein interaction databases

IntActiQ64288. 1 interactor.
MINTiMINT-272016.
STRINGi10090.ENSMUSP00000095882.

Structurei

Secondary structure

1163
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi10 – 14Combined sources5
Helixi19 – 34Combined sources16
Beta strandi50 – 56Combined sources7
Beta strandi61 – 83Combined sources23
Turni89 – 91Combined sources3
Helixi96 – 98Combined sources3
Beta strandi104 – 108Combined sources5
Beta strandi110 – 112Combined sources3
Beta strandi115 – 117Combined sources3
Helixi119 – 135Combined sources17
Beta strandi137 – 145Combined sources9
Helixi151 – 153Combined sources3
Beta strandi154 – 162Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1F35X-ray2.30A/B2-163[»]
1JOBX-ray2.40A2-163[»]
1JODX-ray3.20A/B2-163[»]
ProteinModelPortaliQ64288.
SMRiQ64288.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ64288.

Family & Domainsi

Sequence similaritiesi

Belongs to the olfactory marker protein family.Curated

Phylogenomic databases

eggNOGiENOG410IZPX. Eukaryota.
ENOG410YJIN. LUCA.
GeneTreeiENSGT00390000009497.
HOGENOMiHOG000236315.
HOVERGENiHBG007595.
InParanoidiQ64288.
OMAiHWTPDLT.
OrthoDBiEOG091G0OS2.
PhylomeDBiQ64288.
TreeFamiTF330820.

Family and domain databases

Gene3Di2.60.120.390. 1 hit.
InterProiIPR009103. Olfactory_marker.
[Graphical view]
PANTHERiPTHR15357. PTHR15357. 1 hit.
PfamiPF06554. Olfactory_mark. 1 hit.
[Graphical view]
ProDomiPD022055. Olfactory_marker. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF63697. SSF63697. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q64288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEDGPQKQQ LEMPLVLDQD LTQQMRLRVE SLKQRGEKKQ DGEKLIRPAE
60 70 80 90 100
SVYRLDFIQQ QKLQFDHWNV VLDKPGKVTI TGTSQNWTPD LTNLMTRQLL
110 120 130 140 150
DPAAIFWRKE DSDAMDWNEA DALEFGERLS DLAKIRKVMY FLITFGEGVE
160
PANLKASVVF NQL
Length:163
Mass (Da):18,867
Last modified:January 23, 2007 - v3
Checksum:iD50EA5937D7EAE16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02557 Unassigned DNA. Translation: AAA18415.1.
U01213 Genomic DNA. Translation: AAA20486.1.
BC046600 mRNA. Translation: AAH46600.1.
CCDSiCCDS21466.1.
PIRiB54261.
RefSeqiNP_035140.1. NM_011010.2.
UniGeneiMm.440368.

Genome annotation databases

EnsembliENSMUST00000098281; ENSMUSP00000095882; ENSMUSG00000074006.
GeneIDi18378.
KEGGimmu:18378.
UCSCiuc009ike.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02557 Unassigned DNA. Translation: AAA18415.1.
U01213 Genomic DNA. Translation: AAA20486.1.
BC046600 mRNA. Translation: AAH46600.1.
CCDSiCCDS21466.1.
PIRiB54261.
RefSeqiNP_035140.1. NM_011010.2.
UniGeneiMm.440368.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1F35X-ray2.30A/B2-163[»]
1JOBX-ray2.40A2-163[»]
1JODX-ray3.20A/B2-163[»]
ProteinModelPortaliQ64288.
SMRiQ64288.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ64288. 1 interactor.
MINTiMINT-272016.
STRINGi10090.ENSMUSP00000095882.

PTM databases

iPTMnetiQ64288.
PhosphoSitePlusiQ64288.

Proteomic databases

MaxQBiQ64288.
PaxDbiQ64288.
PRIDEiQ64288.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000098281; ENSMUSP00000095882; ENSMUSG00000074006.
GeneIDi18378.
KEGGimmu:18378.
UCSCiuc009ike.1. mouse.

Organism-specific databases

CTDi4975.
MGIiMGI:97436. Omp.

Phylogenomic databases

eggNOGiENOG410IZPX. Eukaryota.
ENOG410YJIN. LUCA.
GeneTreeiENSGT00390000009497.
HOGENOMiHOG000236315.
HOVERGENiHBG007595.
InParanoidiQ64288.
OMAiHWTPDLT.
OrthoDBiEOG091G0OS2.
PhylomeDBiQ64288.
TreeFamiTF330820.

Miscellaneous databases

EvolutionaryTraceiQ64288.
PROiQ64288.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000074006.
CleanExiMM_OMP.
ExpressionAtlasiQ64288. baseline and differential.
GenevisibleiQ64288. MM.

Family and domain databases

Gene3Di2.60.120.390. 1 hit.
InterProiIPR009103. Olfactory_marker.
[Graphical view]
PANTHERiPTHR15357. PTHR15357. 1 hit.
PfamiPF06554. Olfactory_mark. 1 hit.
[Graphical view]
ProDomiPD022055. Olfactory_marker. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF63697. SSF63697. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiOMP_MOUSE
AccessioniPrimary (citable) accession number: Q64288
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.