Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q641Y6 (PPM1J_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein phosphatase 1J
EC=3.1.3.16
Alternative name(s):
Protein phosphatase 2C isoform zeta
Short name=PP2C-zeta
Gene names
Name:Ppm1j
Synonyms:Ppp2cz
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length504 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphoprotein + H2O = a protein + phosphate.

Subunit structure

Interacts with UBE2I/UBC9 By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   Molecular functionHydrolase
Protein phosphatase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein dephosphorylation

Inferred from electronic annotation. Source: Compara

   Molecular_functionprotein serine/threonine phosphatase activity

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 504504Protein phosphatase 1J
PRO_0000289060

Regions

Domain119 – 496378PP2C-like

Amino acid modifications

Modified residue751Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q641Y6 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 66A1BD3CAA69D8D8

FASTA50455,211
        10         20         30         40         50         60 
MLNRVRSAVA HLVSSSGTSS QRSKSPDLPK AISPPPGALE TPKSPGTKSG NEIPAPQKTA 

        70         80         90        100        110        120 
ETPVSFSRPT FLQLSPGGLR RADDHVGRAV QSPPDTGRRL PWSTGYAEVI NAGKSRHNED 

       130        140        150        160        170        180 
QACCEVVYVE SRRSITGVSR EPSHNQGFSF YYWGLFDGHA GGGAAEMASR LLHRHIREQL 

       190        200        210        220        230        240 
KDLVEILQDP LPPPLCLPST PGTPGVSSPS QLVSPQSWSP QKEVTHDSLV VGAIENAFQL 

       250        260        270        280        290        300 
MDEQMARERR GHLVEGGCCA LVVVYLLGKM YVANAGDSRA IIVRNGEIIP MSREFTPETE 

       310        320        330        340        350        360 
RQRLQLLGFL KPELLGSEFT HLEFPRRVQP KELGQRMLYR DQNMTGWAYK KIELEDLRFP 

       370        380        390        400        410        420 
LVCGEGKKAR VMATIGVTRG LGDHNLKVCS STLPIKPFLS CFPEVRVYDL TQYEHCPDDV 

       430        440        450        460        470        480 
LVLGTDGLWD VTNDSEVAAT VDRVLSTYEP NDPSRYTALA QALVLGARGI PRDRGWRLPN 

       490        500 
NKLGSGDDIS VFVIPLGGPG SSYS

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC082053 mRNA. Translation: AAH82053.1.
IPIIPI00471651.
RefSeqNP_001005540.1. NM_001005540.1.
UniGeneRn.12833.

3D structure databases

ProteinModelPortalQ641Y6.
ModBaseSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000016833.

Proteomic databases

PaxDbQ641Y6.
PRIDEQ641Y6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000016833; ENSRNOP00000016833; ENSRNOG00000012481.
GeneID295341.
KEGGrno:295341.
UCSCRGD:1359104. rat.

Organism-specific databases

CTD333926.
RGD1359104. Ppm1j.

Phylogenomic databases

eggNOGNOG314780.
GeneTreeENSGT00530000063231.
HOGENOMHOG000251606.
HOVERGENHBG105802.
InParanoidQ641Y6.
OMARMLYRDQ.
OrthoDBEOG42JNRC.

Gene expression databases

GenevestigatorQ641Y6.

Family and domain databases

Gene3D3.60.40.10. 3 hits.
InterProIPR001932. PP2C-like.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 2 hits.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. PP2C-related. 1 hit.
PROSITEPS01032. PP2C. False negative.
[Graphical view]
ProtoNetSearch...

Other

NextBio639411.

Entry information

Entry namePPM1J_RAT
AccessionPrimary (citable) accession number: Q641Y6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 25, 2004
Last modified: April 3, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents