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Q641Y6

- PPM1J_RAT

UniProt

Q641Y6 - PPM1J_RAT

Protein

Protein phosphatase 1J

Gene

Ppm1j

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (25 Oct 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    GO - Molecular functioni

    1. protein serine/threonine phosphatase activity Source: Ensembl

    GO - Biological processi

    1. protein dephosphorylation Source: Ensembl

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein phosphatase 1J (EC:3.1.3.16)
    Alternative name(s):
    Protein phosphatase 2C isoform zeta
    Short name:
    PP2C-zeta
    Gene namesi
    Name:Ppm1j
    Synonyms:Ppp2cz
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 2

    Organism-specific databases

    RGDi1359104. Ppm1j.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 504504Protein phosphatase 1JPRO_0000289060Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei75 – 751PhosphoserineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ641Y6.
    PRIDEiQ641Y6.

    Expressioni

    Gene expression databases

    GenevestigatoriQ641Y6.

    Interactioni

    Subunit structurei

    Interacts with UBE2I/UBC9.By similarity

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000016833.

    Structurei

    3D structure databases

    ProteinModelPortaliQ641Y6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini119 – 496378PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiNOG314780.
    GeneTreeiENSGT00530000063231.
    HOGENOMiHOG000251606.
    HOVERGENiHBG105802.
    InParanoidiQ641Y6.
    KOiK17504.
    OMAiDHNLKVC.
    OrthoDBiEOG7F511J.
    PhylomeDBiQ641Y6.
    TreeFamiTF314700.

    Family and domain databases

    Gene3Di3.60.40.10. 3 hits.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 2 hits.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 3 hits.

    Sequencei

    Sequence statusi: Complete.

    Q641Y6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLNRVRSAVA HLVSSSGTSS QRSKSPDLPK AISPPPGALE TPKSPGTKSG    50
    NEIPAPQKTA ETPVSFSRPT FLQLSPGGLR RADDHVGRAV QSPPDTGRRL 100
    PWSTGYAEVI NAGKSRHNED QACCEVVYVE SRRSITGVSR EPSHNQGFSF 150
    YYWGLFDGHA GGGAAEMASR LLHRHIREQL KDLVEILQDP LPPPLCLPST 200
    PGTPGVSSPS QLVSPQSWSP QKEVTHDSLV VGAIENAFQL MDEQMARERR 250
    GHLVEGGCCA LVVVYLLGKM YVANAGDSRA IIVRNGEIIP MSREFTPETE 300
    RQRLQLLGFL KPELLGSEFT HLEFPRRVQP KELGQRMLYR DQNMTGWAYK 350
    KIELEDLRFP LVCGEGKKAR VMATIGVTRG LGDHNLKVCS STLPIKPFLS 400
    CFPEVRVYDL TQYEHCPDDV LVLGTDGLWD VTNDSEVAAT VDRVLSTYEP 450
    NDPSRYTALA QALVLGARGI PRDRGWRLPN NKLGSGDDIS VFVIPLGGPG 500
    SSYS 504
    Length:504
    Mass (Da):55,211
    Last modified:October 25, 2004 - v1
    Checksum:i66A1BD3CAA69D8D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC082053 mRNA. Translation: AAH82053.1.
    RefSeqiNP_001005540.1. NM_001005540.1.
    UniGeneiRn.12833.

    Genome annotation databases

    EnsembliENSRNOT00000016833; ENSRNOP00000016833; ENSRNOG00000012481.
    GeneIDi295341.
    KEGGirno:295341.
    UCSCiRGD:1359104. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC082053 mRNA. Translation: AAH82053.1 .
    RefSeqi NP_001005540.1. NM_001005540.1.
    UniGenei Rn.12833.

    3D structure databases

    ProteinModelPortali Q641Y6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000016833.

    Proteomic databases

    PaxDbi Q641Y6.
    PRIDEi Q641Y6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000016833 ; ENSRNOP00000016833 ; ENSRNOG00000012481 .
    GeneIDi 295341.
    KEGGi rno:295341.
    UCSCi RGD:1359104. rat.

    Organism-specific databases

    CTDi 333926.
    RGDi 1359104. Ppm1j.

    Phylogenomic databases

    eggNOGi NOG314780.
    GeneTreei ENSGT00530000063231.
    HOGENOMi HOG000251606.
    HOVERGENi HBG105802.
    InParanoidi Q641Y6.
    KOi K17504.
    OMAi DHNLKVC.
    OrthoDBi EOG7F511J.
    PhylomeDBi Q641Y6.
    TreeFami TF314700.

    Miscellaneous databases

    NextBioi 639411.
    PROi Q641Y6.

    Gene expression databases

    Genevestigatori Q641Y6.

    Family and domain databases

    Gene3Di 3.60.40.10. 3 hits.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 2 hits.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 3 hits.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.

    Entry informationi

    Entry nameiPPM1J_RAT
    AccessioniPrimary (citable) accession number: Q641Y6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: October 25, 2004
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3