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Protein

Protein phosphatase 1J

Gene

Ppm1j

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1J (EC:3.1.3.16)
Alternative name(s):
Protein phosphatase 2C isoform zeta
Short name:
PP2C-zeta
Gene namesi
Name:Ppm1j
Synonyms:Ppp2cz
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1359104 Ppm1j

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002890601 – 504Protein phosphatase 1JAdd BLAST504

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei41PhosphothreonineBy similarity1
Modified residuei65PhosphoserineBy similarity1
Modified residuei75PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ641Y6
PRIDEiQ641Y6

PTM databases

CarbonylDBiQ641Y6
iPTMnetiQ641Y6
PhosphoSitePlusiQ641Y6

Expressioni

Gene expression databases

GenevisibleiQ641Y6 RN

Interactioni

Subunit structurei

Interacts with UBE2I/UBC9.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ641Y6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 496PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST394

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG1323 Eukaryota
ENOG410XP4B LUCA
HOGENOMiHOG000251606
HOVERGENiHBG105802
InParanoidiQ641Y6
KOiK17504
OrthoDBiEOG091G05FH
PhylomeDBiQ641Y6
TreeFamiTF314700

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 2 hits
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 3 hits
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q641Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNRVRSAVA HLVSSSGTSS QRSKSPDLPK AISPPPGALE TPKSPGTKSG
60 70 80 90 100
NEIPAPQKTA ETPVSFSRPT FLQLSPGGLR RADDHVGRAV QSPPDTGRRL
110 120 130 140 150
PWSTGYAEVI NAGKSRHNED QACCEVVYVE SRRSITGVSR EPSHNQGFSF
160 170 180 190 200
YYWGLFDGHA GGGAAEMASR LLHRHIREQL KDLVEILQDP LPPPLCLPST
210 220 230 240 250
PGTPGVSSPS QLVSPQSWSP QKEVTHDSLV VGAIENAFQL MDEQMARERR
260 270 280 290 300
GHLVEGGCCA LVVVYLLGKM YVANAGDSRA IIVRNGEIIP MSREFTPETE
310 320 330 340 350
RQRLQLLGFL KPELLGSEFT HLEFPRRVQP KELGQRMLYR DQNMTGWAYK
360 370 380 390 400
KIELEDLRFP LVCGEGKKAR VMATIGVTRG LGDHNLKVCS STLPIKPFLS
410 420 430 440 450
CFPEVRVYDL TQYEHCPDDV LVLGTDGLWD VTNDSEVAAT VDRVLSTYEP
460 470 480 490 500
NDPSRYTALA QALVLGARGI PRDRGWRLPN NKLGSGDDIS VFVIPLGGPG

SSYS
Length:504
Mass (Da):55,211
Last modified:October 25, 2004 - v1
Checksum:i66A1BD3CAA69D8D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082053 mRNA Translation: AAH82053.1
RefSeqiNP_001005540.1, NM_001005540.1
UniGeneiRn.12833

Genome annotation databases

GeneIDi295341
KEGGirno:295341
UCSCiRGD:1359104 rat

Similar proteinsi

Entry informationi

Entry nameiPPM1J_RAT
AccessioniPrimary (citable) accession number: Q641Y6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 25, 2004
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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