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Protein

Protein phosphatase 1J

Gene

Ppm1j

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1J (EC:3.1.3.16)
Alternative name(s):
Protein phosphatase 2C isoform zeta
Short name:
PP2C-zeta
Gene namesi
Name:Ppm1j
Synonyms:Ppp2cz
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1359104. Ppm1j.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002890601 – 504Protein phosphatase 1JAdd BLAST504

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei41PhosphothreonineBy similarity1
Modified residuei65PhosphoserineBy similarity1
Modified residuei75PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ641Y6.
PRIDEiQ641Y6.

PTM databases

iPTMnetiQ641Y6.
PhosphoSitePlusiQ641Y6.

Expressioni

Gene expression databases

BgeeiENSRNOG00000012481.
GenevisibleiQ641Y6. RN.

Interactioni

Subunit structurei

Interacts with UBE2I/UBC9.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ641Y6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 496PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST394

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG1323. Eukaryota.
ENOG410XP4B. LUCA.
HOGENOMiHOG000251606.
HOVERGENiHBG105802.
InParanoidiQ641Y6.
KOiK17504.
OrthoDBiEOG091G05FH.
PhylomeDBiQ641Y6.
TreeFamiTF314700.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiView protein in Pfam
PF00481. PP2C. 2 hits.
SMARTiView protein in SMART
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiView protein in PROSITE
PS51746. PPM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q641Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNRVRSAVA HLVSSSGTSS QRSKSPDLPK AISPPPGALE TPKSPGTKSG
60 70 80 90 100
NEIPAPQKTA ETPVSFSRPT FLQLSPGGLR RADDHVGRAV QSPPDTGRRL
110 120 130 140 150
PWSTGYAEVI NAGKSRHNED QACCEVVYVE SRRSITGVSR EPSHNQGFSF
160 170 180 190 200
YYWGLFDGHA GGGAAEMASR LLHRHIREQL KDLVEILQDP LPPPLCLPST
210 220 230 240 250
PGTPGVSSPS QLVSPQSWSP QKEVTHDSLV VGAIENAFQL MDEQMARERR
260 270 280 290 300
GHLVEGGCCA LVVVYLLGKM YVANAGDSRA IIVRNGEIIP MSREFTPETE
310 320 330 340 350
RQRLQLLGFL KPELLGSEFT HLEFPRRVQP KELGQRMLYR DQNMTGWAYK
360 370 380 390 400
KIELEDLRFP LVCGEGKKAR VMATIGVTRG LGDHNLKVCS STLPIKPFLS
410 420 430 440 450
CFPEVRVYDL TQYEHCPDDV LVLGTDGLWD VTNDSEVAAT VDRVLSTYEP
460 470 480 490 500
NDPSRYTALA QALVLGARGI PRDRGWRLPN NKLGSGDDIS VFVIPLGGPG

SSYS
Length:504
Mass (Da):55,211
Last modified:October 25, 2004 - v1
Checksum:i66A1BD3CAA69D8D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082053 mRNA. Translation: AAH82053.1.
RefSeqiNP_001005540.1. NM_001005540.1.
UniGeneiRn.12833.

Genome annotation databases

GeneIDi295341.
KEGGirno:295341.
UCSCiRGD:1359104. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPPM1J_RAT
AccessioniPrimary (citable) accession number: Q641Y6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 25, 2004
Last modified: July 5, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families