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Q641Y6

- PPM1J_RAT

UniProt

Q641Y6 - PPM1J_RAT

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Protein

Protein phosphatase 1J

Gene
Ppm1j, Ppp2cz
Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

  1. protein serine/threonine phosphatase activity Source: Ensembl

GO - Biological processi

  1. protein dephosphorylation Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1J (EC:3.1.3.16)
Alternative name(s):
Protein phosphatase 2C isoform zeta
Short name:
PP2C-zeta
Gene namesi
Name:Ppm1j
Synonyms:Ppp2cz
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 2

Organism-specific databases

RGDi1359104. Ppm1j.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 504504Protein phosphatase 1JPRO_0000289060Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei75 – 751Phosphoserine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ641Y6.
PRIDEiQ641Y6.

Expressioni

Gene expression databases

GenevestigatoriQ641Y6.

Interactioni

Subunit structurei

Interacts with UBE2I/UBC9 By similarity.

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016833.

Structurei

3D structure databases

ProteinModelPortaliQ641Y6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini119 – 496378PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Phylogenomic databases

eggNOGiNOG314780.
GeneTreeiENSGT00530000063231.
HOGENOMiHOG000251606.
HOVERGENiHBG105802.
InParanoidiQ641Y6.
KOiK17504.
OMAiDHNLKVC.
OrthoDBiEOG7F511J.
PhylomeDBiQ641Y6.
TreeFamiTF314700.

Family and domain databases

Gene3Di3.60.40.10. 3 hits.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 3 hits.

Sequencei

Sequence statusi: Complete.

Q641Y6-1 [UniParc]FASTAAdd to Basket

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MLNRVRSAVA HLVSSSGTSS QRSKSPDLPK AISPPPGALE TPKSPGTKSG    50
NEIPAPQKTA ETPVSFSRPT FLQLSPGGLR RADDHVGRAV QSPPDTGRRL 100
PWSTGYAEVI NAGKSRHNED QACCEVVYVE SRRSITGVSR EPSHNQGFSF 150
YYWGLFDGHA GGGAAEMASR LLHRHIREQL KDLVEILQDP LPPPLCLPST 200
PGTPGVSSPS QLVSPQSWSP QKEVTHDSLV VGAIENAFQL MDEQMARERR 250
GHLVEGGCCA LVVVYLLGKM YVANAGDSRA IIVRNGEIIP MSREFTPETE 300
RQRLQLLGFL KPELLGSEFT HLEFPRRVQP KELGQRMLYR DQNMTGWAYK 350
KIELEDLRFP LVCGEGKKAR VMATIGVTRG LGDHNLKVCS STLPIKPFLS 400
CFPEVRVYDL TQYEHCPDDV LVLGTDGLWD VTNDSEVAAT VDRVLSTYEP 450
NDPSRYTALA QALVLGARGI PRDRGWRLPN NKLGSGDDIS VFVIPLGGPG 500
SSYS 504
Length:504
Mass (Da):55,211
Last modified:October 25, 2004 - v1
Checksum:i66A1BD3CAA69D8D8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC082053 mRNA. Translation: AAH82053.1.
RefSeqiNP_001005540.1. NM_001005540.1.
UniGeneiRn.12833.

Genome annotation databases

EnsembliENSRNOT00000016833; ENSRNOP00000016833; ENSRNOG00000012481.
GeneIDi295341.
KEGGirno:295341.
UCSCiRGD:1359104. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC082053 mRNA. Translation: AAH82053.1 .
RefSeqi NP_001005540.1. NM_001005540.1.
UniGenei Rn.12833.

3D structure databases

ProteinModelPortali Q641Y6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000016833.

Proteomic databases

PaxDbi Q641Y6.
PRIDEi Q641Y6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000016833 ; ENSRNOP00000016833 ; ENSRNOG00000012481 .
GeneIDi 295341.
KEGGi rno:295341.
UCSCi RGD:1359104. rat.

Organism-specific databases

CTDi 333926.
RGDi 1359104. Ppm1j.

Phylogenomic databases

eggNOGi NOG314780.
GeneTreei ENSGT00530000063231.
HOGENOMi HOG000251606.
HOVERGENi HBG105802.
InParanoidi Q641Y6.
KOi K17504.
OMAi DHNLKVC.
OrthoDBi EOG7F511J.
PhylomeDBi Q641Y6.
TreeFami TF314700.

Miscellaneous databases

NextBioi 639411.
PROi Q641Y6.

Gene expression databases

Genevestigatori Q641Y6.

Family and domain databases

Gene3Di 3.60.40.10. 3 hits.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 2 hits.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 3 hits.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiPPM1J_RAT
AccessioniPrimary (citable) accession number: Q641Y6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 25, 2004
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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