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Protein

Actin-like protein 7A

Gene

Actl7a

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-like protein 7A
Gene namesi
Name:Actl7a
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1304697 Actl7a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Golgi apparatus, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002828291 – 440Actin-like protein 7AAdd BLAST440

Proteomic databases

PaxDbiQ641W9
PRIDEiQ641W9

PTM databases

PhosphoSitePlusiQ641W9

Expressioni

Tissue specificityi

Detected in testis. Detected at the acrosome of round spermatids (at protein level).1 Publication

Gene expression databases

BgeeiENSRNOG00000016641

Interactioni

Subunit structurei

Interacts (via N-terminus) with TES (via LIM domain 2). Heterodimer with TES; the heterodimer interacts with ENAH to form a heterotrimer.1 Publication

Protein-protein interaction databases

IntActiQ641W9, 1 interactor
STRINGi10116.ENSRNOP00000022395

Structurei

3D structure databases

ProteinModelPortaliQ641W9
SMRiQ641W9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni36 – 56Required for interaction with TESBy similarityAdd BLAST21

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

eggNOGiKOG0676 Eukaryota
COG5277 LUCA
GeneTreeiENSGT00760000118957
HOGENOMiHOG000233340
HOVERGENiHBG003771
InParanoidiQ641W9
OMAiIWEYLFH
OrthoDBiEOG091G07GC
PhylomeDBiQ641W9
TreeFamiTF354237

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR027679 ACTL7A
IPR031769 ACTL7A_N
PANTHERiPTHR11937 PTHR11937, 1 hit
PTHR11937:SF167 PTHR11937:SF167, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 1 hit
PF16840 ACTL7A_N, 1 hit
PRINTSiPR00190 ACTIN
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q641W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLDAVWAPQ TANIGDGPAK KASDQTSMQT QVLQTASLRD GPAKRAVWVR
60 70 80 90 100
RDNAEKEEPV KSAVSKDRPR LEVTKAVVVD LGTGFCKCGF AGLPKPTHKI
110 120 130 140 150
STTVGKPYME TAKTGDNRKE TFVGRELFNP DIHLKLVNPL RHGIIVDWDT
160 170 180 190 200
VQDIWEYLFR QEMKIAPEEH AVLVSDPPLS PHTNREKYAE MLFETFNTPA
210 220 230 240 250
MHIAYQSRLS MYSYGRTSGL VVEVGHGVSY VVPIYEGYPL PSITGRLDYA
260 270 280 290 300
GSDLTNYLMN LMNNCGKHFS EDHLSIVEDI KTKCCFVALD PIEEKKIPPS
310 320 330 340 350
EHEIHYTLPD GKEIRLGQER FLCSEMFFKP SLIKSMQLGL HTQTVSCLNK
360 370 380 390 400
CDIALKRDLM GNILLCGGST MLRGFPNRLQ KELSSMCPND TPQVNVLPER
410 420 430 440
DTAVWTGGSI LASLQGFQPL WVHRLEYEEH GPFFLYRRCF
Length:440
Mass (Da):49,568
Last modified:October 25, 2004 - v1
Checksum:iEE38C1EA8098D653
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082101 mRNA Translation: AAH82101.1
RefSeqiNP_001011973.1, NM_001011973.1
XP_008761929.1, XM_008763707.2
UniGeneiRn.103609

Genome annotation databases

EnsembliENSRNOT00000022395; ENSRNOP00000022395; ENSRNOG00000016641
GeneIDi298017
KEGGirno:298017
UCSCiRGD:1304697 rat

Similar proteinsi

Entry informationi

Entry nameiACL7A_RAT
AccessioniPrimary (citable) accession number: Q641W9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: October 25, 2004
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health