Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q641F1

- UBCP1_XENLA

UniProt

Q641F1 - UBCP1_XENLA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ubiquitin-like domain-containing CTD phosphatase 1

Gene

ublcp1

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Magnesium.By similarity

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-like domain-containing CTD phosphatase 1 (EC:3.1.3.16)
Alternative name(s):
Nuclear proteasome inhibitor UBLCP1
Gene namesi
Name:ublcp1
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-5892757. ublcp1.

Subcellular locationi

Nucleus By similarity
Note: Colocalizes with nuclear proteasomes.By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 318318Ubiquitin-like domain-containing CTD phosphatase 1PRO_0000242646Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ641F1.
SMRiQ641F1. Positions 3-79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 8179Ubiquitin-likePROSITE-ProRule annotationAdd
BLAST
Domaini133 – 294162FCP1 homologyPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 294162PhosphataseBy similarityAdd
BLAST

Domaini

The Ubiquitin-like domain mediates interaction with proteasomes.By similarity

Sequence similaritiesi

Contains 1 FCP1 homology domain.PROSITE-ProRule annotation
Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG080207.
KOiK17618.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR011943. HAD-SF_hydro_IIID.
IPR004274. NIF.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF03031. NIF. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00577. CPDc. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR02245. HAD_IIID1. 1 hit.
PROSITEiPS50969. FCP1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q641F1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLSLIIKWG GQEFPLSALS EEDTVLDLKH SLKSLTGVLP ERMKLLGLKY
60 70 80 90 100
KGKPAENDVK LGVLRLKPNT KIMMMGTREE SLEEMMAPPP DNDEVVNDFD
110 120 130 140 150
IDEEVVEVEN REENLAKISR RVKDYKVEVL NPPREGKKLL VLDVDYTLFD
160 170 180 190 200
HRSCAETGQE LMRPYLHEFL SSAYEDYDIV IWSATSMKWI EAKMKELGVT
210 220 230 240 250
TNANYKITFM LDSAAMITVH TPRRGLVDVK PLGVIWGKYG EFYSKNNTIM
260 270 280 290 300
FDDIGRNFLM NPQNGLKIRP FMKAHLNRDK DKELVKLSQY LKEIAQLDDL
310
SELNHKHWER YLAKKQGQ
Length:318
Mass (Da):36,740
Last modified:October 25, 2004 - v1
Checksum:i170DD5F968C32891
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC082386 mRNA. Translation: AAH82386.1.
RefSeqiNP_001087860.1. NM_001094391.1.
UniGeneiXl.15737.

Genome annotation databases

GeneIDi447721.
KEGGixla:447721.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC082386 mRNA. Translation: AAH82386.1 .
RefSeqi NP_001087860.1. NM_001094391.1.
UniGenei Xl.15737.

3D structure databases

ProteinModelPortali Q641F1.
SMRi Q641F1. Positions 3-79.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 447721.
KEGGi xla:447721.

Organism-specific databases

CTDi 134510.
Xenbasei XB-GENE-5892757. ublcp1.

Phylogenomic databases

HOVERGENi HBG080207.
KOi K17618.

Family and domain databases

Gene3Di 3.40.50.1000. 1 hit.
InterProi IPR023214. HAD-like_dom.
IPR011943. HAD-SF_hydro_IIID.
IPR004274. NIF.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF03031. NIF. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view ]
SMARTi SM00577. CPDc. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view ]
SUPFAMi SSF54236. SSF54236. 1 hit.
SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR02245. HAD_IIID1. 1 hit.
PROSITEi PS50969. FCP1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.

Entry informationi

Entry nameiUBCP1_XENLA
AccessioniPrimary (citable) accession number: Q641F1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 25, 2004
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3