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Protein

Cytochrome c, somatic

Gene

cycs

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei15Heme (covalent)PROSITE-ProRule annotation1
Binding sitei18Heme (covalent)PROSITE-ProRule annotation1
Metal bindingi19Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi81Iron (heme axial ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c, somatic
Gene namesi
Name:cycs
ORF Names:TTpA002h20.1
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5931974. cyct.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001082572 – 105Cytochrome c, somaticAdd BLAST104

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylglycineBy similarity1

Post-translational modificationi

Binds 1 heme group per subunit.By similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ640U4.
PRIDEiQ640U4.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000018532.

Structurei

3D structure databases

ProteinModelPortaliQ640U4.
SMRiQ640U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Phylogenomic databases

eggNOGiKOG3453. Eukaryota.
COG3474. LUCA.
HOGENOMiHOG000009762.
HOVERGENiHBG003023.
InParanoidiQ640U4.
KOiK08738.
OrthoDBiEOG091G0UQY.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiView protein in InterPro
IPR009056. Cyt_c-like_dom.
IPR036909. Cyt_c-like_dom_sf.
IPR002327. Cyt_c_1A/1B.
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiView protein in Pfam
PF00034. Cytochrom_C. 1 hit.
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiView protein in PROSITE
PS51007. CYTC. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q640U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDVEKGKKI FVQKCAQCHT VEKTGKHKTG PNLWGLFGRK TGQAPGFSYT
60 70 80 90 100
DANKSKGIVW GEDTLFEYLE NPKKYIPGTK MIFAGIKKKN ERADLIAYLK

KSTSE
Length:105
Mass (Da):11,758
Last modified:January 23, 2007 - v3
Checksum:i1B6EE9163A497CA7
GO

Sequence cautioni

The sequence CAJ83237 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR760771 mRNA. Translation: CAJ83237.1. Different initiation.
BC082495 mRNA. Translation: AAH82495.1.
RefSeqiNP_001008176.1. NM_001008175.1.
XP_012825804.1. XM_012970350.2.
UniGeneiStr.46288.

Genome annotation databases

GeneIDi493538.
KEGGixtr:493538.

Similar proteinsi

Entry informationi

Entry nameiCYC1_XENTR
AccessioniPrimary (citable) accession number: Q640U4
Secondary accession number(s): Q28HR6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 92 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  2. SIMILARITY comments
    Index of protein domains and families