Q640T1 (ALLC_XENTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Allantoicase
EC=3.5.3.4

Alternative name(s):
Allantoate amidinohydrolase

Gene names

Name:

allc

Organism

Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Taxonomic identifier

8364 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Utilization of purines as secondary nitrogen sources, when primary sources are limiting By similarity.
Catalytic activity	Allantoate + H2O = (S)-ureidoglycolate + urea.
Pathway	Nitrogen metabolism; (S)-allantoin degradation; (S)-ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
Sequence similarities	Belongs to the allantoicase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	allantoicase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 389	389	Allantoicase		PRO_0000205911
Experimental info
	Sequence conflict	257	1	R → S in AAM74031. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q640T1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: EBFF4D5AC4DE6741	FASTA	389	43,618
	10 20 30 40 50 60 MSAPPKENIG LPVSEFVQMN NLACESVGGK VLFATDDCFA PAENLLKKKD PEFKPGLFTE 70 80 90 100 110 120 FGKWMDGWET RRKRIPGHDW CIIELGVPGI IHGFEADTRF FTGNYAPRIS VQAACLKPEE 130 140 150 160 170 180 ITFQPRKDKI GTAASIEEYK SADKLKSEKW SHLLQMTELT PGYAESSHSY FNVNSKQRWT 190 200 210 220 230 240 HLRLNIYPDG GIARFKVYGI GQRDWSSCKP NDLEDLLSMV NGGVCLGFSD AHYGHPRNLI 250 260 270 280 290 300 GIGRACDMGD GWETARRLDR PPVLKADSKG ILQVPGFEWA VLKLGHPGLV THIEIDTNHF 310 320 330 340 350 360 KGNSPNSCKI DACALTPTEE EGVKRDERFE IGYNWKPLLS VTQIHPHKRR YVESTSLALH 370 380 QVISHVKITI APDGGVSRIR LWGFPRPLP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]	"Selective pressure on the allantoicase gene during vertebrate evolution." Vigetti D., Binelli G., Monetti C., Prati M., Bernardini G., Gornati R. J. Mol. Evol. 57:650-658(2003) [PubMed: 14745534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 66-258.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC082508 mRNA. Translation: AAH82508.1. AF480058 mRNA. Translation: AAM74031.1.
RefSeq	NP_001162026.1. NM_001168554.1.
UniGene	Str.120.
3D structure databases
ProteinModelPortal	Q640T1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q640T1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	394447.
KEGG	xtr:394447.
Organism-specific databases
CTD	55821.
Xenbase	XB-GENE-1002643. allc.
Phylogenomic databases
eggNOG	veNOG08243.
GeneTree	ENSGT00390000001793.
HOGENOM	HBG480577.
HOVERGEN	HBG004209.
InParanoid	Q640T1.
OrthoDB	EOG4SJ5DT.
Gene expression databases
Bgee	Q640T1.
Family and domain databases
InterPro	IPR005164. Allantoicase. IPR015908. Allantoicase_dom. IPR008979. Galactose-bd-like. [Graphical view]
KO	K01477.
PANTHER	PTHR12045. Allantoicase. 1 hit.
Pfam	PF03561. Allantoicase. 2 hits. [Graphical view]
PIRSF	PIRSF016516. Allantoicase. 1 hit.
SUPFAM	SSF49785. Gal_bind_like. 2 hits.
TIGRFAMs	TIGR02961. Allantoicase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLC_XENTR

Accession

Primary (citable) accession number: Q640T1
Secondary accession number(s): Q8JHV2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	October 25, 2004
Last modified:	November 16, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program