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Q63ZW6

- Q63ZW6_MOUSE

UniProt

Q63ZW6 - Q63ZW6_MOUSE

Protein
Submitted name:

Col4a5 protein

Gene

Col4a5

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 99 (01 Oct 2014)
      Sequence version 1 (25 Oct 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. extracellular matrix structural constituent Source: InterPro

    GO - Biological processi

    1. neuromuscular junction development Source: MGI

    Enzyme and pathway databases

    ReactomeiREACT_196595. Anchoring fibril formation.
    REACT_196606. ECM proteoglycans.
    REACT_196607. Non-integrin membrane-ECM interactions.
    REACT_198984. Collagen biosynthesis and modifying enzymes.
    REACT_199046. Assembly of collagen fibrils and other multimeric structures.
    REACT_199055. Collagen degradation.
    REACT_202342. Laminin interactions.
    REACT_206066. Extracellular matrix organization.
    REACT_216309. Integrin cell surface interactions.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Col4a5 proteinImported
    Submitted name:
    Protein Col4a5Imported
    Gene namesi
    Name:Col4a5Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:88456. Col4a5.

    Subcellular locationi

    GO - Cellular componenti

    1. basal lamina Source: MGI
    2. basement membrane Source: MGI
    3. collagen type IV trimer Source: MGI
    4. neuromuscular junction Source: MGI

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ63ZW6.

    Family & Domainsi

    Keywords - Domaini

    CollagenSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00720000108691.
    HOGENOMiHOG000085652.
    HOVERGENiHBG004933.
    InParanoidiQ63ZW6.
    KOiK06237.
    OMAiNCIGTGV.
    TreeFamiTF344135.

    Family and domain databases

    Gene3Di2.170.240.10. 1 hit.
    InterProiIPR016187. C-type_lectin_fold.
    IPR008160. Collagen.
    IPR001442. Collagen_VI_NC.
    [Graphical view]
    PfamiPF01413. C4. 2 hits.
    PF01391. Collagen. 19 hits.
    [Graphical view]
    SMARTiSM00111. C4. 2 hits.
    [Graphical view]
    SUPFAMiSSF56436. SSF56436. 2 hits.
    PROSITEiPS51403. NC1_IV. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q63ZW6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQVRGVCLAA GWFLLALCLW GQPAEAAACH GCSSGSKCDC SGIKGEKGER     50
    GFPGLEGHPG LPGFPGPEGP PGPRGQKGDD GIPGPPGPKG IRGPPGLPGF 100
    PGTPGLPGMP GHDGAPGPQG IPGCNGTKGE RGFPGSPGFP GLQGPPGPPG 150
    IPGMKGEPGS IIMSPLPGPK GNQGYPGPPG IQGPPGPKGI SGPSGPPGPP 200
    GLMGPPGPPG PPGPKGNMGL NFQGPKGEKG EQGLQGPPGP PGQISEQKRP 250
    IDIEFQKGDQ GVPGDRGPPG PPGIPGPPGP PGGVKGEKGE PGEAGKRGKP 300
    GKDGETGQPG IPGLPGDPGY PGEPGRDGEK GQKGDIGPPG PPGLVIPAPG 350
    TGVTMGEKGN IGLPGLPGEK GERGFPGIQG PPGFPGPPGT AVVGPPGPPG 400
    YPGERGQKGD EGPPGICIPG SPGLDGQPGA PGLPGPPGPP GPQLPSRDEI 450
    CKAGPPGPPG PPGDKGLQGE RGVKGDKGDT CFNCIGTGIS GPPGQPGLPG 500
    LPGPPGSLGI PGEKGDKGQA GITGPKGLPG IPGPPGAPGF PGSKGDPGDV 550
    LTLPGMKGDK GELGFPGAPG LPGLPGSPGK DGLPGLPGPK GEPGGITFKG 600
    ERGPPGSPGL PGLPGNMGPT GPVGFGPPGP IGEKGIQGVA GNPGQPGLPG 650
    PKGDPGQTIT QPGKPGLPGS PGRDGEVGLP GDPGLPGQPG LPGIPGSKGE 700
    PGIPGIGPPG PPGPKGFPGI PGPPGAPGAP GRMGPDGPPG PPGFPGPKGE 750
    PGFGLPGPPG PPGFPGFKGT PGPKGDRGFP GPSGPPGRTG LDGLPGPKGD 800
    VGPNGQPGPV GPPGLPGIGL QGPPGPPGTP GPIGQPGLHG IPGEKGDPGP 850
    PGFDVPGLPG ERGSPGLPGA PGLIGPPGSP GVPGKAGVPG FPGVKGEMGM 900
    MGPPGPPGPL GIPGRSGAPG LKGDDGMQGQ PGLPGPAGEK GGKGEPGLPG 950
    PPGPMHPDFL GSKGEKGEPG LPGIPGLSGP KGYQGLPGDP GQPGLSGQPG 1000
    SPGLPGPKGN PGLPGPPGLT GPPGPKGNIG DMGFPGPQGV DGPPGPPGFP 1050
    GQPGSPGLPG QKGSKGEPGV SGIGLPGLPG PKGEPGLPGY PGNPGIKGSV 1100
    GETGLPGLPG NPGAKGQPGL PGFPGTPGLP GPKGMNGPPG NPGFPGEPGP 1150
    VGAGGRPGPP GPPGEKGKPG QDGIPGPAGQ KGEPGQPGFG IPGPPGLPGL 1200
    SGQKGDGGSP GLPGNPGLPG SKGEPGFQGF PGMPGPPGPP GSPGQALEGP 1250
    KGNPGPQGPP GRPGPPGFQG PPGTEGPRGP PGNGGIKGER GNPGPPGQPG 1300
    LPGLKGDQGP PGLPGNPGRP GLNGMKGDPG LPGVPGFPGM KGPIGVPGST 1350
    GPDGEPGLTG PPGPPGLPGP SGQSIVIKGD PGPPGIPGQP GLKGLPGLPG 1400
    PQGLPGPIGP PGDPGRNGLP GFDGAGGRKG DPGLPGQPGA RGLDGPPGPD 1450
    GLQGPPGPPG TTSVAHGFLI TRHSQTTEAP QCPRGTVHIY EGFSLLYVQG 1500
    NKRAHGQDLG TAGSCLRRFS TMPFMFCNIN NVCNFASRND YSYWLSTPEP 1550
    MPMNMEPLKG QSIQPFISRC AVCEAPAVVI AVHSQTIQIP HCPQGWDSLW 1600
    IGYSFMMHTS AGAEGSGQAL ASPGSCLEEF RSAPFIECHG RGTCNYYANS 1650
    YSFWLATVDM SDMFNKPQSE TLKAGDLRTR ISRCQVCMKR T 1691
    Length:1,691
    Mass (Da):161,807
    Last modified:October 25, 2004 - v1
    Checksum:iE5CD42658128DD07
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL671856 Genomic DNA. No translation available.
    AL713983 Genomic DNA. No translation available.
    BX571779 Genomic DNA. No translation available.
    BC082788 mRNA. Translation: AAH82788.1.
    AK133179 mRNA. Translation: BAE21544.1.
    RefSeqiNP_001156627.1. NM_001163155.1.
    NP_031762.2. NM_007736.4.
    UniGeneiMm.286892.

    Genome annotation databases

    EnsembliENSMUST00000112930; ENSMUSP00000108552; ENSMUSG00000031274.
    ENSMUST00000112931; ENSMUSP00000108553; ENSMUSG00000031274.
    GeneIDi12830.
    KEGGimmu:12830.
    UCSCiuc009uln.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL671856 Genomic DNA. No translation available.
    AL713983 Genomic DNA. No translation available.
    BX571779 Genomic DNA. No translation available.
    BC082788 mRNA. Translation: AAH82788.1 .
    AK133179 mRNA. Translation: BAE21544.1 .
    RefSeqi NP_001156627.1. NM_001163155.1.
    NP_031762.2. NM_007736.4.
    UniGenei Mm.286892.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000112930 ; ENSMUSP00000108552 ; ENSMUSG00000031274 .
    ENSMUST00000112931 ; ENSMUSP00000108553 ; ENSMUSG00000031274 .
    GeneIDi 12830.
    KEGGi mmu:12830.
    UCSCi uc009uln.2. mouse.

    Organism-specific databases

    CTDi 1287.
    MGIi MGI:88456. Col4a5.

    Phylogenomic databases

    GeneTreei ENSGT00720000108691.
    HOGENOMi HOG000085652.
    HOVERGENi HBG004933.
    InParanoidi Q63ZW6.
    KOi K06237.
    OMAi NCIGTGV.
    TreeFami TF344135.

    Enzyme and pathway databases

    Reactomei REACT_196595. Anchoring fibril formation.
    REACT_196606. ECM proteoglycans.
    REACT_196607. Non-integrin membrane-ECM interactions.
    REACT_198984. Collagen biosynthesis and modifying enzymes.
    REACT_199046. Assembly of collagen fibrils and other multimeric structures.
    REACT_199055. Collagen degradation.
    REACT_202342. Laminin interactions.
    REACT_206066. Extracellular matrix organization.
    REACT_216309. Integrin cell surface interactions.

    Miscellaneous databases

    NextBioi 282330.
    PROi Q63ZW6.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q63ZW6.

    Family and domain databases

    Gene3Di 2.170.240.10. 1 hit.
    InterProi IPR016187. C-type_lectin_fold.
    IPR008160. Collagen.
    IPR001442. Collagen_VI_NC.
    [Graphical view ]
    Pfami PF01413. C4. 2 hits.
    PF01391. Collagen. 19 hits.
    [Graphical view ]
    SMARTi SM00111. C4. 2 hits.
    [Graphical view ]
    SUPFAMi SSF56436. SSF56436. 2 hits.
    PROSITEi PS51403. NC1_IV. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: Mammary tumor. C3Imported.
    7. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    8. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    11. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ63ZW6_MOUSE
    AccessioniPrimary (citable) accession number: Q63ZW6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 25, 2004
    Last sequence update: October 25, 2004
    Last modified: October 1, 2014
    This is version 99 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3