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Protein

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase

Gene

b3gat1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

UDP-alpha-D-glucuronate + [protein]-3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine = UDP + [protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine.UniRule annotation

Cofactori

Mn2+UniRule annotation

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotation
LigandManganeseUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT43. Glycosyltransferase Family 43.

Names & Taxonomyi

Protein namesi
Recommended name:
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferaseUniRule annotation (EC:2.4.1.135UniRule annotation)
Gene namesi
Name:b3gat1Imported
Synonyms:LOC494776Imported
ORF Names:XELAEV_18011318mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componenti: Chromosome 2l

Organism-specific databases

XenbaseiXB-GENE-5956393. b3gat1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatusUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501050627223 – 342Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferaseSequence analysisAdd BLAST320

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 43 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Signal-anchorUniRule annotation, Transmembrane

Phylogenomic databases

HOVERGENiHBG050650.

Family and domain databases

CDDicd00218. GlcAT-I. 1 hit.
Gene3Di3.90.550.10. 1 hit.
InterProiView protein in InterPro
IPR005027. Glyco_trans_43.
IPR029044. Nucleotide-diphossugar_trans.
PANTHERiPTHR10896. PTHR10896. 1 hit.
PfamiView protein in Pfam
PF03360. Glyco_transf_43. 1 hit.
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

Q63ZM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRRRNLLTT LLIVLPWALL FTLWHQHPTT RYLNLLRKDA GDNSTSKPLF
60 70 80 90 100
HNVTPAKEED LHCGHQHATR ETPVVVRTYV YSRPPPWSED IPTIYVITPT
110 120 130 140 150
YSRPVQKAEL VRLANTFLHV VNLHWIVVED SPRKTKLVAN LLEKAGINFT
160 170 180 190 200
HLNVESPRSL KVGLSRMPSH SPRGTTQRNL GLRWLRDNIN ASNPPEGVVY
210 220 230 240 250
FADDDNTYSL ELFEEMRYTR KVSVWPVAFV GGLRYESPRV SPSGRVVGWK
260 270 280 290 300
TVFDPNRPFA IDMAGFAISL KLILERPQAN FRLEGIKGGY QETSLLKDLV
310 320 330 340
TMDGLEAKAA NCTKVLVWHT RAERPTLVNE GKRGFTDPNI EV
Length:342
Mass (Da):38,964
Last modified:October 25, 2004 - v1
Checksum:i1A74CD6AD7F517CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082886 mRNA. Translation: AAH82886.1.
CM004468 Genomic DNA. Translation: OCT93643.1.
RefSeqiNP_001088079.1. NM_001094610.1.
UniGeneiXl.8747.

Genome annotation databases

GeneIDi494776.

Similar proteinsi

Entry informationi

Entry nameiQ63ZM6_XENLA
AccessioniPrimary (citable) accession number: Q63ZM6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: November 22, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported