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Protein

Alpha-1,4 glucan phosphorylase

Gene

pygl

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.UniRule annotation

Catalytic activityi

((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase
Biological processCarbohydrate metabolismUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Protein family/group databases

CAZyiGT35. Glycosyltransferase Family 35.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,4 glucan phosphorylaseUniRule annotation (EC:2.4.1.1UniRule annotation)
Gene namesi
Name:pyglImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-865172. pygl.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei681N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

MaxQBiQ63ZG6.

Structurei

3D structure databases

ProteinModelPortaliQ63ZG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycogen phosphorylase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG006848.
KOiK00688.

Family and domain databases

CDDicd04300. GT1_Glycogen_Phosphorylase. 1 hit.
InterProiView protein in InterPro
IPR011833. Glycg_phsphrylas.
IPR000811. Glyco_trans_35.
IPR035090. Pyridoxal_P_attach_site.
PANTHERiPTHR11468. PTHR11468. 1 hit.
PfamiView protein in Pfam
PF00343. Phosphorylase. 1 hit.
PIRSFiPIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMsiTIGR02093. P_ylase. 1 hit.
PROSITEiView protein in PROSITE
PS00102. PHOSPHORYLASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q63ZG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKPLTDQEK RKQISIRGIV GVENVAELKK GFNRHLHFTL VKDRNVATIR
60 70 80 90 100
DYYFALAHTV RDHLVGRWIR TQQYYYEKDP KRTYYLSLEF YIGRTLQNTM
110 120 130 140 150
INLGLQNACD EAIYQLGLDI EELEEMEEDA GLGNGGLGRL AACFLDSMAT
160 170 180 190 200
LGLAAYGYGI RYEYGIFNQK IKDGWQAEEA DDWLRHGNPW EKARPEFMLP
210 220 230 240 250
VHFYGRVEST KTGPRWVDTQ VVLAMPYDTP VPGYMNNTVN TMRLWSARAP
260 270 280 290 300
NDFNLRDFNV GDYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV
310 320 330 340 350
VAASLQDIIR RFKASKLGCR DSVRTAFDSF PEKVAIQLND THPALGIPEL
360 370 380 390 400
MRAFLDIEKL PWDKAWEITK KTFAYTNHTV LPEALERWPV DLFEKLLPRH
410 420 430 440 450
LQIIYEINQK HLEKISSLFP GDHGRLRRMS LIEEDGVKRI NMAHLCIVGS
460 470 480 490 500
HAVNGVAKIH SDIVKNEVFK DFSELEPKKF QNKTNGITPR RWLLLCNPGL
510 520 530 540 550
AELIAEKIGE DYVKDLSQLT QLKKFVDDNS FIRDISKVKE DNKLKFSQFL
560 570 580 590 600
EKEYKMKINP SSMFDVHVKR IHEYKRQLLN CLHIITMYNR IKANPSKDFV
610 620 630 640 650
PRTVIIGGKA APGYHMAKMI IKLITSVGDI VNHDPAVGNK LKVIYLENYR
660 670 680 690 700
VSLAEKVIPA TDLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM
710 720 730 740 750
AEEAGEENIF IFGMRVEDVA EVDKKGYNAN EYYEKLPELK KAIDQIKSGF
760 770 780 790 800
FSPAKPDLFK DVVNMLFNHD RFKVFADYEA YIKCQDKVSE LYKTPKEWTK
810 820 830 840 850
MVIKNIAASG KFSSDRTIKE YAKDIWGVEP SDLKIPPPNE PRDVVDDAGA

GKAKA
Length:855
Mass (Da):97,887
Last modified:October 25, 2004 - v1
Checksum:iCF666BF33BAC938A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082952 mRNA. Translation: AAH82952.1.
RefSeqiNP_001088127.1. NM_001094658.1.
UniGeneiXl.29142.

Genome annotation databases

GeneIDi494832.
KEGGixla:494832.

Similar proteinsi

Entry informationi

Entry nameiQ63ZG6_XENLA
AccessioniPrimary (citable) accession number: Q63ZG6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: October 25, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)