ID   Q63XS4_BURPS            Unreviewed;       546 AA.
AC   Q63XS4;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:CAH34454.1};
GN   OrderedLocusNames=BPSL0465 {ECO:0000313|EMBL:CAH34454.1};
OS   Burkholderia pseudomallei (strain K96243).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH34454.1, ECO:0000313|Proteomes:UP000000605};
RN   [1] {ECO:0000313|EMBL:CAH34454.1, ECO:0000313|Proteomes:UP000000605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K96243 {ECO:0000313|EMBL:CAH34454.1,
RC   ECO:0000313|Proteomes:UP000000605};
RX   PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA   Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA   Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA   Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA   Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA   Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA   Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA   Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA   Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT   "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT   pseudomallei.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; BX571965; CAH34454.1; -; Genomic_DNA.
DR   RefSeq; WP_004543739.1; NZ_CP009538.1.
DR   RefSeq; YP_107091.1; NC_006350.1.
DR   AlphaFoldDB; Q63XS4; -.
DR   STRING; 272560.BPSL0465; -.
DR   KEGG; bps:BPSL0465; -.
DR   PATRIC; fig|272560.51.peg.1191; -.
DR   eggNOG; COG0840; Bacteria.
DR   Proteomes; UP000000605; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR033480; sCache_2.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF17200; sCache_2; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM01049; Cache_2; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000605};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        187..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          221..265
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          270..499
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   546 AA;  57086 MW;  0489FDB7B5DC11DB CRC64;
     MNRMSLNRKL WLALALVWVG LLGVGAWSAF ETRTTMLAER KEGMANLVDS AAGVVKAYYA
     LAQSGKMSDE DARRDALERI AAMRYGDSGY LFVMDSKPVV LMHPTLPKLV GTQVGDYLDP
     DGKRLFVTIL NAAKAGGHGF AEYRGRLPHS ETAVPKISYV TRFAPWDWNI SSGVFLKDID
     TVYYETLVGH LAVVFVIGLV ITAAMLVIIR NVRASLGGEP DEAASLAARI AAGDLTRPVA
     VRAGDGTSMM AAMRDMQGRL RSTIGGIRRA AESIAAASHE IASGNHDLSQ RTEQQAASLE
     ETAASMEELT ATVKQNAENA RQASGLANNA SEIALKGNDV VSRVIGTMGE INDSSRKIAD
     IIGVIDGIAF QTNILALNAA VEAARAGEQG RGFAVVAGEV RSLAQRSATA AKEIKQLIDA
     SVERVNNGSA LVGQAGETMT EILQAVRRVT DIMGEIAAAS EEQSSGISQV GRAVTQMDEM
     TQQNAALVEE AAAAASSLQE QAARLRESVS AFQVGDGAAA GAGAAAGVVG GPNAAASSGC
     VEPALA
//