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Q63WJ4 (Q63WJ4_BURPS) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CAH34889.1
Ordered Locus Names:BPSL0896 EMBL CAH34889.1
OrganismBurkholderia pseudomallei (strain K96243) [Reference proteome] [HAMAP] EMBL CAH34889.1
Taxonomic identifier272560 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
Q63WJ4 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: F85E7112F2CB3C69

FASTA41946,146
        10         20         30         40         50         60 
MPYQHIKVPE GGDKITVNKD FSLNVSDQPI IPYIEGDGTG FDITPVMIKV VDAAVEKAYG 

        70         80         90        100        110        120 
GKKKIHWMEI YAGEKATKVY GPDVWLPEET LQVLKEYVVS IKGPLTTPVG GGIRSLNVAL 

       130        140        150        160        170        180 
RQELDLYVCL RPIQYFKGVP SPVREPEKTN MVIFRENSED IYAGIEWAAE SEQAKKVIKF 

       190        200        210        220        230        240 
LQEEMGVKKI RFPQTSGIGI KPVSKEGTER LVRKAIQYAI DNDRKSVTLV HKGNIMKFTE 

       250        260        270        280        290        300 
GAFRDAGYAL AQKEFGAELI DGGPWMKFKN PKTGNEIVVK DSIADAFLQQ ILLRPAEYDV 

       310        320        330        340        350        360 
IATLNLNGDY ISDALAAQVG GIGIAPGANL SDSVAMFEAT HGTAPKYAGK DYVNPGSEIL 

       370        380        390        400        410 
SAEMMLRHLG WTEAADVIIS AMEKSIKQKR VTYDFARLME GATQVSCSGF GQVLIENME 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571965 Genomic DNA. Translation: CAH34889.1.
RefSeqYP_107522.1. NC_006350.1.

3D structure databases

ProteinModelPortalQ63WJ4.
SMRQ63WJ4. Positions 6-418.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272560.BPSL0896.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH34889; CAH34889; BPSL0896.
GeneID3092199.
KEGGbps:BPSL0896.
PATRIC19261493. VBIBurPse99623_0976.

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMARYAIDND.
OrthoDBEOG6SNDTP.

Enzyme and pathway databases

BioCycBPSE272560:GJNI-911-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ63WJ4_BURPS
AccessionPrimary (citable) accession number: Q63WJ4
Entry history
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)