Q63W00 (TAL_BURPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	BPSL1095

Organism

Burkholderia pseudomallei (Pseudomonas pseudomallei)

Taxonomic identifier

28450 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	317 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm By similarity HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 317	317	Transaldolase HAMAP MF_00492		PRO_0000230946
Sites
	Active site	126	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q63W00 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: F7DC4E0CB742C75B	FASTA	317	35,373
	10 20 30 40 50 60 MTTALDQLKQ YTTVVADTGD FQQLAQYKPQ DATTNPSLIL KAVQKDAYRP ILEKTVRDHA 70 80 90 100 110 120 GESVGFIIDR LLIAFGTEIL KLIPGRVSTE VDARLSFDTQ RSIDKGREII KLYEAAGVGR 130 140 150 160 170 180 ERVLIKLAST WEGIRAAEVL QREGIRCNMT LLFSLVQAAA CAEAGAQLIS PFVGRIYDWY 190 200 210 220 230 240 KKQKGADWDE AQDGGANDPG VQSVRRIYTY YKHFGYRTEV MGASFRTTSQ ITELAGCDLL 250 260 270 280 290 300 TISPELLQKL HDSTEAVARK LSPDEARDAR LERVAIDESS FRFQLNDDAM ATEKLAEGIR 310 LFSADAVKLE KMIEALR

References

[1]

"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei." Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L. , Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004) [PubMed: 15377794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K96243.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571965 Genomic DNA. Translation: CAH35088.1.
RefSeq	YP_107716.1. NC_006350.1.
3D structure databases
ProteinModelPortal	Q63W00.
SMR	Q63W00. Positions 2-316.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3094101.
GenomeReviews	Gene locus BPSL1095 in contig BX571965_GR.
KEGG	bps:BPSL1095.
PATRIC	19261921. VBIBurPse99623_1188.
Phylogenomic databases
HOGENOM	HBG286747.
OMA	GCEILAI.
PhylomeDB	Q63W00.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	BPSE272560:BPSL1095-MONOMER.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. TalAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_BURPS

Accession

Primary (citable) accession number: Q63W00

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program