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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Burkholderia pseudomallei (strain K96243)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei350Proton donorUniRule annotation1
Active sitei381UniRule annotation1
Active sitei503UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBPSE272560:G1G3Q-1474-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:BPSL1413
OrganismiBurkholderia pseudomallei (strain K96243)
Taxonomic identifieri272560 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000000605 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001806151 – 540Glucose-6-phosphate isomeraseAdd BLAST540

Proteomic databases

PRIDEiQ63V31

Interactioni

Protein-protein interaction databases

STRINGi272560.BPSL1413

Structurei

3D structure databases

ProteinModelPortaliQ63V31
SMRiQ63V31
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.101 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q63V31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLNSLPVWP ALQAHYEEIR DAHLRDWFAP ANDRAPTRAE RFTFEGGGLA
60 70 80 90 100
ADFSKNRLTD ATLALLVRLA REAGVEARRD AMFAGETVNP TEGRAALHTA
110 120 130 140 150
LRANAPDAPF QAQVAAERAK MARFADAVRS GAWTGYTGKR IRHVVNIGIG
160 170 180 190 200
GSDLGPKMVV HALHHVATPD IATHFVSNVD GADLARVLER IDPEATLAII
210 220 230 240 250
VSKTFTTLET MTNARSLRDW FVANGCPEGA LAKHFVGVSA NPAEVVKFGI
260 270 280 290 300
AEANVFEMWD WVGGRYSLWS AVGLSIMIAI GPERFDELLA GARDMDEHFR
310 320 330 340 350
TAPLERNLPV LQGLVGIWYR NFFGAQSYLV APYSEALHYL PSYLQQLEME
360 370 380 390 400
SNGKSARIDG AFVDYPTSAV TWGEPGTNGQ HAFFQMLHQG PTLVPIDFIA
410 420 430 440 450
VLTPEHPLAS HHPKLLANCF AQSEALMLGR TLDEARKIVG PAKPELAPHL
460 470 480 490 500
TFPGNRPTTT LLVDALTPRT LGALIALYEH KVLVQAAVWN INPFDQWGVE
510 520 530 540
LGKILGKVVE ADLTAAQVDP AKHDSSTSAL IARARKALGE
Length:540
Mass (Da):58,813
Last modified:October 25, 2004 - v1
Checksum:iFDAA623198B30BB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571965 Genomic DNA Translation: CAH35415.1
RefSeqiWP_004527211.1, NZ_CP009538.1
YP_108035.1, NC_006350.1

Genome annotation databases

EnsemblBacteriaiCAH35415; CAH35415; BPSL1413
GeneIDi3093521
KEGGibps:BPSL1413
PATRICifig|272560.51.peg.3432

Similar proteinsi

Entry informationi

Entry nameiG6PI_BURPS
AccessioniPrimary (citable) accession number: Q63V31
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: October 25, 2004
Last modified: February 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome