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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Burkholderia pseudomallei (strain K96243)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi8Divalent metal cationUniRule annotation1
Metal bindingi9Divalent metal cationUniRule annotation1
Metal bindingi39Divalent metal cationUniRule annotation1
Metal bindingi92Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:BPSL1502
OrganismiBurkholderia pseudomallei (strain K96243)
Taxonomic identifieri272560 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000000605 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002355981 – 2535'-nucleotidase SurEAdd BLAST253

Interactioni

Protein-protein interaction databases

STRINGi272560.BPSL1502.

Structurei

3D structure databases

ProteinModelPortaliQ63UU4.
SMRiQ63UU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122500.
KOiK03787.
OMAiDCVHIAL.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiView protein in InterPro
IPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
IPR036523. SurE-like_sf.
PfamiView protein in Pfam
PF01975. SurE. 1 hit.
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q63UU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILLSNDDG YLAPGLAALY EALRPLAEIL VMAPEQNCSG ASNSLTLSRP
60 70 80 90 100
LSVSRSAATG FYYVNGTPTD SVHVALTGML DTKPDLVVSG INNGQNMGDD
110 120 130 140 150
TLYSGTVAAA TEGIMFGVPA IAFSLVHKEW AHLGDAARVA AEIVRHYLDH
160 170 180 190 200
PLPGQPLLNI NIPNLPYEEL KGWRVTRLGK RHPSQPVIRQ TNPRGEPIYW
210 220 230 240 250
IGAAGDALDA SEGTDFHATA SGYVSITPLQ LDLTHTQMLA ATRDWARAGS

GAS
Length:253
Mass (Da):26,985
Last modified:October 25, 2004 - v1
Checksum:i3CFCC204D47F1593
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571965 Genomic DNA. Translation: CAH35503.1.
RefSeqiWP_004527164.1. NZ_CP009538.1.
YP_108122.1. NC_006350.1.

Genome annotation databases

EnsemblBacteriaiCAH35503; CAH35503; BPSL1502.
GeneIDi3092285.
KEGGibps:BPSL1502.
PATRICifig|272560.51.peg.3538.

Similar proteinsi

Entry informationi

Entry nameiSURE_BURPS
AccessioniPrimary (citable) accession number: Q63UU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 25, 2004
Last modified: October 25, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families