ID   Q63TU2_BURPS            Unreviewed;       570 AA.
AC   Q63TU2;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:CAH35874.1};
GN   OrderedLocusNames=BPSL1875 {ECO:0000313|EMBL:CAH35874.1};
OS   Burkholderia pseudomallei (strain K96243).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH35874.1, ECO:0000313|Proteomes:UP000000605};
RN   [1] {ECO:0000313|EMBL:CAH35874.1, ECO:0000313|Proteomes:UP000000605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K96243 {ECO:0000313|EMBL:CAH35874.1,
RC   ECO:0000313|Proteomes:UP000000605};
RX   PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA   Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA   Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA   Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA   Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA   Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA   Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA   Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA   Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT   "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT   pseudomallei.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; BX571965; CAH35874.1; -; Genomic_DNA.
DR   RefSeq; WP_004538333.1; NZ_CP009538.1.
DR   RefSeq; YP_108474.1; NC_006350.1.
DR   AlphaFoldDB; Q63TU2; -.
DR   STRING; 272560.BPSL1875; -.
DR   KEGG; bps:BPSL1875; -.
DR   PATRIC; fig|272560.51.peg.4011; -.
DR   eggNOG; COG0840; Bacteria.
DR   Proteomes; UP000000605; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000605};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        232..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          254..311
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          316..545
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   570 AA;  61687 MW;  9280890AF3AB4EB5 CRC64;
     MGFLNTFSLR RYASLLLGLL AVAAVAIGLC QWRLDAANHR VAQAYQQRYV STQLANELRR
     SSDDLTRLAR TYVATGDAKW EQQYNEILAI RSGKAPRPLD YDRIYWDFRA ADEPLRAEQG
     ETISLQEMMK RAGFTDEEFA KLHDAEQNSN DLVKTETVAM NLVKGLTPDD AGHFTKQGSP
     DLEKARALMF DANYHRFKAK IMHPIDDFLK LLDARTEGAI ARAQASAQTW KIISAAVAIG
     ILAFFALMLH MMFKRVLAGL EAAASTASRV AAGDLTSHFD AHRVDPQAKD EISRVMRALQ
     TMNDGLVRIV TDVRSGTDTI ATASHEIMAG NNDLSARTEQ QAASLQETAA SMSELTATVK
     LNLENARQAN MIGSNAVSTV EKGSVSVEQL VTTVNAISTN SGKIADIISL IEGIAFQTNI
     LALNAAVEAA RAGEQGRGFA VVASEVRSLA QRSSSAAKEI KDLIETSIDT VRDGVSKADE
     VGQHIVEVKQ AIRRVADLVG EITAASEEQT RGIEQVDAAV SQMDRVTQQN AALVEQAAAA
     SKAMDDQAGN LRAAASIFKL PGRASLFAHA
//