SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q63S63

- PNCB_BURPS

UniProt

Q63S63 - PNCB_BURPS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, BPSL2462
Organism
Burkholderia pseudomallei (strain K96243)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciBPSE272560:GJNI-2521-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:BPSL2462
OrganismiBurkholderia pseudomallei (strain K96243)
Taxonomic identifieri272560 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
ProteomesiUP000000605: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_0000205826Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272560.BPSL2462.

Structurei

3D structure databases

ProteinModelPortaliQ63S63.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiSIVCKVI.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q63S63-1 [UniParc]FASTAAdd to Basket

« Hide

MIITSLLDTD LYKFTMMQVV LHHFPAASVE YRFKCRTPGV DLVPYIDEIR    50
AEVRSLCELR FTDSELDYLR RLRFVKSDFV DFLALFHLNE KYISITPSQK 100
GGGEIDIEIK GPWLHTILFE IPVLAIVNEV YFRNTQRRPD YREGRGRLRE 150
KIKLLGAKPE FADCKIADYG TRRRFSKVWH EEVLRTLQDG LGPQFAGTSN 200
VYYAMTHEIT PLGTMAHEYL QACQALGPRL RDSQTYGLEM WAKEYRGDLG 250
IALSDVYGMD AFLRDFDMYF CKLFDGARHD SGDPFDWGER LIKHYEENRC 300
DPRTKVLVFS DALDIPKVMQ LYARFRGRCK LAFGVGTNLT NDLGYQPLQI 350
VIKMVRCNGQ PVAKLSDSPG KSMCDDKAYL AYLRQVFGIT QPPDDDAGK 399
Length:399
Mass (Da):45,962
Last modified:October 25, 2004 - v1
Checksum:i64300451032C4FA1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571965 Genomic DNA. Translation: CAH36465.1.
RefSeqiYP_109054.1. NC_006350.1.

Genome annotation databases

EnsemblBacteriaiCAH36465; CAH36465; BPSL2462.
GeneIDi3091463.
KEGGibps:BPSL2462.
PATRICi19265199. VBIBurPse99623_2804.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571965 Genomic DNA. Translation: CAH36465.1 .
RefSeqi YP_109054.1. NC_006350.1.

3D structure databases

ProteinModelPortali Q63S63.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272560.BPSL2462.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAH36465 ; CAH36465 ; BPSL2462 .
GeneIDi 3091463.
KEGGi bps:BPSL2462.
PATRICi 19265199. VBIBurPse99623_2804.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi SIVCKVI.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci BPSE272560:GJNI-2521-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K96243.

Entry informationi

Entry nameiPNCB_BURPS
AccessioniPrimary (citable) accession number: Q63S63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: October 25, 2004
Last modified: September 3, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi