Q63S15 (Q63S15_BURPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Name:	cysM EMBL CAH36513.1
Ordered Locus Names:	BPSL2507

Organism

Burkholderia pseudomallei (strain K96243) [Reference proteome] [HAMAP]

Taxonomic identifier

272560 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group › Burkholderia pseudomallei

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985 EMBL CAH36513.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular_function	cysteine synthase activity Inferred from electronic annotation. Source: EC transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q63S15 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 7830194979D7FA3C	FASTA	300	32,565
	10 20 30 40 50 60 MAYKTIEDTI GNTPLVQLVR LPDDEIRARN NVILAKLEGN NPAGSVKDRP ALSMIRKAEE 70 80 90 100 110 120 RGTIKPGDTL IEATSGNTGI ALAMAAAIRG YKMVLIMPED LSIERRQSMA AYGAEIVLTP 130 140 150 160 170 180 VKGGMEFARD LADQMQREGK GVILDQFANP DNPLAHYEGT GPEIWRETEG RVTHFVSAMG 190 200 210 220 230 240 TTGTIMGTSQ YLKERNPTVE IVGAQPEEGS RIPGIRKWPE AYLPKIFDRS RIDRVENVSQ 250 260 270 280 290 300 AASEAMARKL AAVEGIFCGI SSGGACEVAL RVARQAENAT IVFVVCDRGD RYLSTGVFPA

References

[1]

"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei." Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L. , Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K96243.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571965 Genomic DNA. Translation: CAH36513.1.
RefSeq	YP_109102.1. NC_006350.1.
3D structure databases
ProteinModelPortal	Q63S15.
SMR	Q63S15. Positions 5-298.
ModBase	Search...
Protein-protein interaction databases
STRING	272560.BPSL2507.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3092757.
KEGG	bps:BPSL2507.
PATRIC	19265309. VBIBurPse99623_2857.
Phylogenomic databases
HOGENOM	HOG000217394.
KO	K12339.
OMA	CEVALRI.
ProtClustDB	PRK11761.
Enzyme and pathway databases
BioCyc	BPSE272560:GJNI-2571-MONOMER.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR005856. Cys_synthKM. IPR005858. CysM. IPR001926. Trp_syn_b_sub_like_PLP_eny_SF. [Graphical view]
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR01136. cysKM. 1 hit. TIGR01138. cysM. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q63S15_BURPS

Accession

Primary (citable) accession number: Q63S15

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2004
Last sequence update:	October 25, 2004
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)