Reviewed, UniProtKB/Swiss-Prot Q63QS9 (ALLC2_BURPS)

Names and origin

Protein names

Recommended name:
    Probable allantoicase 2
    EC=3.5.3.4
Alternative name(s):
    Allantoate amidinohydrolase 2

Gene names

Name:	alc2
Ordered Locus Names:	BPSL2945

Organism

Burkholderia pseudomallei (Pseudomonas pseudomallei) [Complete proteome] [HAMAP]

Taxonomic identifier

28450 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Allantoate + H2O = (S)-ureidoglycolate + urea. HAMAP MF_00813
Pathway	Nitrogen metabolism; (S)-allantoin degradation; (S)-ureidoglycolate from allantoate (aminidohydrolase route): step 1/1. HAMAP MF_00813
Sequence similarities	Belongs to the allantoicase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: HAMAP purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	allantoicase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 336	336	Probable allantoicase 2 HAMAP MF_00813		PRO_0000205920

Sequences

	Sequence		Length	Mass (Da)
	Q63QS9-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 8433A0EEB794BD93	FASTA	336	36,972
	10 20 30 40 50 60 MAAPILDPNA PAFTRRYMNL ADPRLGAKAL FASDEFFAPK ERMLDPEPAV FIPGKYDDHG 70 80 90 100 110 120 KWMDGWETRR KRTTGHDFCV VRLARPGVVY GVDLDTSHFT GNFPPAASID ACVSDADTPP 130 140 150 160 170 180 DDAVWETLVP ATTLAGNQHH YVDVSNPRAY THLRVNLYPD GGLARLRVYG QPQRDWSRAA 190 200 210 220 230 240 RGELVDLAAI ENGAYLVAAN NEHFGPASRM LMPGRGANMG DGWETRRRRE PGNDWAIVAL 250 260 270 280 290 300 ARPGVIRRVE VDTAHFKGNF PDRCSLQAAR VAGGTDASLV TQAMFWPMLL GEQPLGMDSV 310 320 330 HTFETQLAAL GPVTHVRLNI HPDGGVSRLR LWGELA

References

[1]

"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei." Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L. , Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004) [PubMed: 15377794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K96243.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571965 Genomic DNA. Translation: CAH36955.1.
RefSeq	YP_109539.1.
3D structure databases
SMR	Q63QS9. Positions 12-333.
ModBase	Search...
Genome annotation databases
GeneID	3094036.
GenomeReviews	Gene locus BPSL2945 in contig BX571965_GR.
KEGG	bps:BPSL2945.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG480577.
OMA	DTSYFLG.
Enzyme and pathway databases
BioCyc	BPSE272560:BPSL2945-MONOMER.
BRENDA	3.5.3.4. 275934.
Family and domain databases
HAMAP	MF_00813. Allantoicase. [Tree]
InterPro	IPR005164. Allantoicase. IPR015908. Allantoicase_dom. IPR008979. Galactose-bd-like. [Graphical view]
PANTHER	PTHR12045. Allantoicase. 1 hit.
Pfam	PF03561. Allantoicase. 2 hits. [Graphical view]
PIRSF	PIRSF016516. Allantoicase. 1 hit.
TIGRFAMs	TIGR02961. allantoicase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLC2_BURPS

Accession

Primary (citable) accession number: Q63QS9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	October 25, 2004
Last modified:	February 9, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)