Q63NL2 (SELD_BURPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Selenide, water dikinase
EC=2.7.9.3

Alternative name(s):
Selenium donor protein
Selenophosphate synthase

Gene names

Name:	selD
Ordered Locus Names:	BPSS0287

Organism

Burkholderia pseudomallei (Pseudomonas pseudomallei)

Taxonomic identifier

28450 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity. HAMAP MF_00625
Sequence similarities	Belongs to the selenophosphate synthase 1 family. Class I subfamily.

Ontologies

Keywords
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW selenide, water dikinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 354	354	Selenide, water dikinase HAMAP MF_00625		PRO_0000127617
Regions
	Nucleotide binding	236 – 242	7	ATP Potential
Sites
	Active site	23	1	Potential
	Site	26	1	Important for catalytic activity By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q63NL2 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: B85714CD88F67B8F	FASTA	354	36,078
	10 20 30 40 50 60 MTETKQTDAA APRLTSLSHG GGCGCKIAPG VLSELLRRTA PPALFPDLLV GTETSDDAAV 70 80 90 100 110 120 YRLNDEQAIV ATTDFFMPIV DDPFDFGRIA ATNALSDVYA MGGKPILALA LVGMPINVLP 130 140 150 160 170 180 HETIAAVLRG GEAVCADAGI PVAGGHSIDS VEPIYGLAAL GVVHPARVKR NAAARAGDVL 190 200 210 220 230 240 VLGKPLGVGV LSAALKKDRL DAQGYAQMIA TTTKLNRPGT ALAALPGVHA LTDVTGFGLL 250 260 270 280 290 300 GHTLELARGA GLTARVRYGA LPWLAGVEAL VADGVLTGAS GRNWAAYGHD VRLGDGLPAV 310 320 330 340 350 AQALLTDPQT SGGLLVACAP EAVDDVLACF RDDGFERAAA IGEMVDGAAR VDVS

References

[1]

"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei." Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L. , Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004) [PubMed: 15377794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K96243.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571966 Genomic DNA. Translation: CAH37735.1.
RefSeq	YP_110307.1. NC_006351.1.
3D structure databases
ProteinModelPortal	Q63NL2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3095787.
GenomeReviews	Gene locus BPSS0287 in contig BX571966_GR.
KEGG	bps:BPSS0287.
PATRIC	19268174. VBIBurPse99623_4264.
Phylogenomic databases
HOGENOM	HBG383791.
OMA	DYIAQGC.
ProtClustDB	PRK00943.
Enzyme and pathway databases
BioCyc	BPSE272560:BPSS0287-MONOMER.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. IPR023061. SelD_I. [Graphical view]
KO	K01008.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00476. SelD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_BURPS

Accession

Primary (citable) accession number: Q63NL2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program