Q63LB8 (Q63LB8_BURPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Name:	ald EMBL CAH38558.1
Ordered Locus Names:	BPSS1090

Organism

Burkholderia pseudomallei (Pseudomonas pseudomallei)

Taxonomic identifier

28450 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183 EMBL CAH38558.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q63LB8 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 08F6A350DDBA81EA	FASTA	371	38,368
	10 20 30 40 50 60 MLIGVPKEIK VYEYRVGLTP AGARELALHG HQVLVQRGAG AAIGLQDDDY AAAGAMLAND 70 80 90 100 110 120 AADVYARADM IVKVKEPQPA ECAMLRRGQI LFAYLHLAPD PGQAAALVKS RAVCIAYETV 130 140 150 160 170 180 RAPGGGLPLL APMSEVAGRM SIQVAAAHLE SPGGGMGLLM AGVPGVPAAH VVVIGAGVVG 190 200 210 220 230 240 TCALQMAAGL GARVTVLDTN VDRLRELDLV FGNRIATLYS NTHAIDGAVR GADVVIGAVL 250 260 270 280 290 300 VPGASAPRLV TREMISKMRA GAVVVDVAID QGGCIETSHP TTHAQPTYVV DGVVHYCVAN 310 320 330 340 350 360 MPGAVARTST FALGNATLRH AIALANKGWK RALADDPYLR AGLNVCDGHV THEAVARALG 370 LAYVHADEML D

References

[1]

"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei." Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L. , Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004) [PubMed: 15377794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K96243.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571966 Genomic DNA. Translation: CAH38558.1.
RefSeq	YP_111103.1. NC_006351.1.
3D structure databases
ProteinModelPortal	Q63LB8.
SMR	Q63LB8. Positions 1-370.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3095974.
GenomeReviews	Gene locus BPSS1090 in contig BX571966_GR.
KEGG	bps:BPSS1090.
NMPDR	fig|272560.3.peg.1130.
PATRIC	19270116. VBIBurPse99623_5228.
Phylogenomic databases
HOGENOM	HBG289735.
OMA	AIGYETV.
ProtClustDB	CLSK931331.
Family and domain databases
InterPro	IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q63LB8_BURPS

Accession

Primary (citable) accession number: Q63LB8

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2004
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)